Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer

Keyphrases

• Adenoviral 100%
• Breast Cancer 100%
• High Selectivity 100%
• CXCR4 Promoter 100%
• Conditionally Replicating Adenovirus 100%
• Oncolysis 100%
• Chimerism 100%
• Adenovirus Type 5 57%
• Breast Cancer Cells 28%
• Tumor Cells 28%
• Adenovirus 28%
• Breast Cancer Treatment 28%
• Infectivity 28%
• Human Liver Tissue 28%
• Adenovirus Receptor 28%
• Coxsackie 28%
• Receptor-independent 14%
• Normal Human 14%
• Novel Therapeutics 14%
• Antineoplastic Agents 14%
• Full Potential 14%
• Gene Promoter 14%
• Xenograft 14%
• Therapeutic Approaches 14%
• Cancer Cells 14%
• Normal Breast Tissue 14%
• Mouse Tumor Model 14%
• Breast Cancer Cell Lines 14%
• Primary Breast Cancer 14%
• Tumor Targeting 14%
• Tissue Slices 14%
• Tropism 14%
• Transcriptional Targeting 14%
• Virotherapy 14%
• Serotype 3 14%
• Cancer-specific 14%
• Transcriptional Control 14%
• Fibrous Proteins 14%
• Oncolytic Activity 14%
• Knob Domain 14%
• Infectivity Enhancement 14%
• CXCR4 Gene 14%

Medicine and Dentistry

• Promoter Region 100%
• Breast Cancer 100%
• Conditionally Replicating Adenovirus 100%
• Chimera 100%
• Adenoviridae 85%
• Serotype 71%
• Infection 42%
• Cancer Cell 42%
• Tumor Cell 28%
• Cancer Therapy 28%
• Liver Tissue 28%
• Coxsackie Virus and Adenovirus Receptor 28%
• Malignant Neoplasm 14%
• Anticarcinogen 14%
• Receptor 14%
• Therapeutic Agent 14%
• Neoplasm 14%
• In Vitro 14%
• Xenograft 14%
• Breast Cancer Cell Line 14%
• Virotherapy 14%
• Tissue Slice 14%
• Breast Tissue 14%
• Gene Promoter 14%

Immunology and Microbiology

• Promoter Region 100%
• Adenoviridae 100%
• CXCR4 100%
• Chimera 100%
• Conditionally Replicating Adenovirus 87%
• Serotype 62%
• Cancer Cell 37%
• Tumor Cell 25%
• Liver Tissue 25%
• Mouse Model 12%
• Normal Human 12%
• Xenograft 12%
• Breast Tissue 12%
• Breast Cancer Cell Line 12%
• Tissue Slice 12%
• Virotherapy 12%