@article{eb280a1b1269498e807598c8ca4a0f97,
title = "Circulating Cell-Free Mitochondrial DNA in Pregnancy",
abstract = "Circulating cell-free mitochondrial DNA (ccf-mtDNA) released upon cell injury or death stimulates diverse pattern recognition receptors to activate innate immune responses and initiate systemic inflammation. In this review, we discuss the temporal changes of ccf-mtDNA during pregnancy and its potential contribution to adverse pregnancy outcomes in pregnancy complications.",
keywords = "circulating DNA, gestation, maternal, mitochondria, preeclampsia",
author = "Bradshaw, {Jessica L.} and Cushen, {Spencer C.} and Phillips, {Nicole R.} and Styliani Goulopoulou",
note = "Funding Information: Research in the authors{\textquoteright} laboratories is supported by National Institutes of Health Grants R01 HL-0146562, HL-0146562-02S1, and T32 AG 020494; American Heart Association Grants 19TPA34850131 and AHA903250; and the Texas Alzheimer{\textquoteright}s Research and Care Consortium. Publisher Copyright: {\textcopyright} 2022 Int. Union Physiol. Sci./Am. Physiol. Soc.",
year = "2022",
month = jul,
doi = "10.1152/physiol.00037.2021",
language = "English",
volume = "37",
pages = "187--196",
journal = "Physiology",
issn = "1548-9213",
publisher = "American Physiological Society",
number = "4",
}