Abstract
In rats, bilateral electrolytic lesions of either the ventromedial hypothalamus or the septal nuclei, when combined with a high-cholesterol diet, produced elevation of total plasma cholesterol. The similar pattern of results produced by lesions in two discrete brain regions suggests that altered cholesterol metabolism may be a consequence of the common behavior, aggression, that these lesions produce. In addition, high-density lipoprotein cholesterol, when expressed as a percentage of total plasma cholesterol, was lower in rats fed a high-cholesterol diet.
Original language | English |
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Pages (from-to) | 473-485 |
Number of pages | 13 |
Journal | Artery |
Volume | 5 |
Issue number | 6 |
State | Published - 1 Jan 1979 |