Abstract
In rats, bilateral electrolytic lesions of either the ventromedial hypothalamus or the septal nuclei, when combined with a high-cholesterol diet, produced elevation of total plasma cholesterol. The similar pattern of results produced by lesions in two discrete brain regions suggests that altered cholesterol metabolism may be a consequence of the common behavior, aggression, that these lesions produce. In addition, high-density lipoprotein cholesterol, when expressed as a percentage of total plasma cholesterol, was lower in rats fed a high-cholesterol diet.
| Original language | English |
|---|---|
| Pages (from-to) | 473-485 |
| Number of pages | 13 |
| Journal | Artery |
| Volume | 5 |
| Issue number | 6 |
| State | Published - 1 Jan 1979 |
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Cholesterol metabolism in the rat following lesions of the diencephalon. / Oglesby, Michael; Lacko, Andras G.; Harrell, E.; Jordan, J.
In: Artery, Vol. 5, No. 6, 01.01.1979, p. 473-485.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cholesterol metabolism in the rat following lesions of the diencephalon
AU - Oglesby, Michael
AU - Lacko, Andras G.
AU - Harrell, E.
AU - Jordan, J.
PY - 1979/1/1
Y1 - 1979/1/1
N2 - In rats, bilateral electrolytic lesions of either the ventromedial hypothalamus or the septal nuclei, when combined with a high-cholesterol diet, produced elevation of total plasma cholesterol. The similar pattern of results produced by lesions in two discrete brain regions suggests that altered cholesterol metabolism may be a consequence of the common behavior, aggression, that these lesions produce. In addition, high-density lipoprotein cholesterol, when expressed as a percentage of total plasma cholesterol, was lower in rats fed a high-cholesterol diet.
AB - In rats, bilateral electrolytic lesions of either the ventromedial hypothalamus or the septal nuclei, when combined with a high-cholesterol diet, produced elevation of total plasma cholesterol. The similar pattern of results produced by lesions in two discrete brain regions suggests that altered cholesterol metabolism may be a consequence of the common behavior, aggression, that these lesions produce. In addition, high-density lipoprotein cholesterol, when expressed as a percentage of total plasma cholesterol, was lower in rats fed a high-cholesterol diet.
UR - http://www.scopus.com/inward/record.url?scp=0018603144&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0018603144
VL - 5
SP - 473
EP - 485
JO - Artery
JF - Artery
SN - 0098-6127
IS - 6
ER -