Chitin-derived AVR-48 prevents experimental bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension in newborn mice

Keyphrases

• Aged Mice 100%
• Alveolar Simplification 25%
• Alveoli 25%
• Angiogenesis 25%
• Bronchoalveolar Lavage Fluid 50%
• Bronchopulmonary Dysplasia 100%
• Care Burden 25%
• Cell Death 50%
• Cell Proliferation 50%
• Cell-to-cell 25%
• Chitin 100%
• Chord Length 50%
• Common Complications 25%
• Complications of Prematurity 25%
• Definitive Treatment 25%
• Drug Candidates 25%
• Experimental Bronchopulmonary Dysplasia 100%
• First Year of Life 25%
• Fulton Index 50%
• High Resource Utilization 25%
• Hospital Costs 25%
• Immunostaining 25%
• Inflammation Markers 25%
• Inflammatory Cells 50%
• Intensive Care Unit Stay 25%
• Life-limiting Conditions 25%
• Long Hospital Stay 25%
• Lung Cells 25%
• Lung Inflammation 25%
• Major Contributor 25%
• Mouse Model 25%
• Mouse Pups 50%
• Neonatal Intensive Care Unit 25%
• Neonatal Mice 25%
• Neonatal Morbidity 25%
• Neonatal Mortality 25%
• Neonatal Rats 25%
• NOAEL 25%
• Pharmacokinetic Study 25%
• Postnatal Day 25%
• Prematurity 25%
• Prophylactic Treatment 25%
• Pulmonary Function 25%
• Pulmonary Hypertension 100%
• Radial Alveolar Count 50%
• Rat Pups 50%
• Rehospitalization 25%
• Resource Utilization 25%
• Safety Margin 25%
• Septal Thickness 50%
• Short Half-life 25%
• Small Molecules 25%
• Toxicity Study 25%
• Treatment Options 25%
• Two-dose 25%
• Western Blotting 25%

Medicine and Dentistry

• Adverse Effect 14%
• Angiogenesis 14%
• Bioavailability 14%
• Bronchoalveolar Lavage Fluid 28%
• Cell Death 28%
• Cell Proliferation 28%
• Chitin 100%
• Diseases 28%
• Enzyme Linked Immunosorbent Assay 14%
• Health Care 14%
• Hospital Cost 14%
• Immunohistochemistry 14%
• Inflammation 14%
• Inflammatory Cell 28%
• Lung Dysplasia 100%
• Lung Function 14%
• Neonatal Infant 100%
• Neonatal Intensive Care Unit 14%
• Newborn Morbidity 14%
• Newborn Mortality 14%
• Pharmacokinetics 14%
• Pimeprofen 14%
• Pneumonia 14%
• Prematurity 28%
• Pulmonary Hypertension 100%
• Treatment Option 14%
• Western Blot 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Bioavailability 14%
• Chitin 100%
• Diseases 28%
• Enzyme-Linked Immunosorbent Assay 14%
• Inflammation 14%
• Lung Dysplasia 100%
• Mouse Model 14%
• Newborn Morbidity 14%
• Newborn Mortality 14%
• No-Observed-Adverse-Effect Level 14%
• Pharmacokinetics 14%
• Pimeprofen 14%
• Pneumonia 14%
• Prematurity 28%
• Pulmonary Hypertension 100%
• Rat 28%
• Western Blot 14%