Chitin-derived AVR-48 prevents experimental bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension in newborn mice

Keyphrases

• Aged Mice 100%
• Chitin 100%
• Pulmonary Hypertension 100%
• Bronchopulmonary Dysplasia 100%
• Cell Proliferation 28%
• Cell Death 28%
• Bronchoalveolar Lavage 28%
• Inflammatory Cells 28%
• Rat Pups 28%
• Radial Alveolar Count 28%
• Septal Thickness 28%
• Chord Length 28%
• Fulton Index 28%
• Mouse Pups 28%
• Western Blotting 14%
• Mouse Model 14%
• Immunostaining 14%
• Angiogenesis 14%
• Pharmacokinetic Study 14%
• Two-dose 14%
• Cell-to-cell 14%
• Postnatal Day 14%
• Inflammation Markers 14%
• Small Molecules 14%
• Treatment Options 14%
• Prophylactic Treatment 14%
• Drug Candidates 14%
• Caregiver Burden 14%
• Hospital Costs 14%
• Neonatal Rats 14%
• Major Contributor 14%
• Rehospitalization 14%
• Neonatal Mice 14%
• Neonatal Intensive Care Unit 14%
• Life-limiting Conditions 14%
• Common Complications 14%
• Pulmonary Function 14%
• Resource Utilization 14%
• Lung Inflammation 14%
• Alveoli 14%
• Lung Cells 14%
• Neonatal Morbidity 14%
• Neonatal Mortality 14%
• First Year of Life 14%
• High Resource Utilization 14%
• Complications of Prematurity 14%
• Long Hospital Stay 14%
• NOAEL 14%
• Alveolar Simplification 14%
• Prematurity 14%
• Safety Margin 14%
• Intensive Care Unit Stay 14%
• Definitive Treatment 14%
• Short Half-life 14%
• Toxicity Study 14%

Medicine and Dentistry

• Neonatal Infant 100%
• Pulmonary Hypertension 100%
• Chitin 100%
• Lung Dysplasia 100%
• Disease 28%
• Cell Death 28%
• Inflammatory Cell 28%
• Prematurity 28%
• Cell Proliferation 28%
• Bronchoalveolar Lavage Fluid 28%
• Bioavailability 14%
• Pharmacokinetics 14%
• Adverse Event 14%
• Health Care 14%
• Immunohistochemistry 14%
• Prophylaxis 14%
• Angiogenesis 14%
• Neonatal Intensive Care Unit 14%
• Enzyme Linked Immunosorbent Assay 14%
• Lung Function 14%
• Hospital Cost 14%
• Newborn Morbidity 14%
• Newborn Mortality 14%
• Pimeprofen 14%
• Pneumonia 14%
• Western Blotting 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Mouse 100%
• Pulmonary Hypertension 100%
• Chitin 100%
• Lung Dysplasia 100%
• Disease 28%
• Prematurity 28%
• Inflammation 14%
• Mouse Model 14%
• Enzyme-Linked Immunosorbent Assay 14%
• Western Blot 14%
• Bioavailability 14%
• Pneumonia 14%
• Pimeprofen 14%
• Newborn Morbidity 14%
• No-Observed-Adverse-Effect Level 14%
• Newborn Mortality 14%
• Pharmacokinetics 14%