Chinese population data on three tetrameric short tandem repeat loci - HUMTHO1, TPOX, and CSF1PO - derived using multiplex PCR and manual typing

Nu En Huang; James Schumm; Bruce Budowle

doi:10.1016/0379-0738(94)01646-M

Chinese population data on three tetrameric short tandem repeat loci - HUMTHO1, TPOX, and CSF1PO - derived using multiplex PCR and manual typing

Nu En Huang, James Schumm, Bruce Budowle

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Abstract

Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.

Original language	English
Pages (from-to)	131-136
Number of pages	6
Journal	Forensic Science International
Volume	71
Issue number	2
DOIs	https://doi.org/10.1016/0379-0738(94)01646-M
State	Published - 30 Jan 1995

Keywords

Chinese
Hardy-Weinberg expectations
Linkage equilibrium
PCR
Polymerase chain reaction
Population databases
STR

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10.1016/0379-0738(94)01646-M

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title = "Chinese population data on three tetrameric short tandem repeat loci - HUMTHO1, TPOX, and CSF1PO - derived using multiplex PCR and manual typing",

abstract = "Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.",

keywords = "Chinese, Hardy-Weinberg expectations, Linkage equilibrium, PCR, Polymerase chain reaction, Population databases, STR",

author = "Huang, {Nu En} and James Schumm and Bruce Budowle",

year = "1995",

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doi = "10.1016/0379-0738(94)01646-M",

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T1 - Chinese population data on three tetrameric short tandem repeat loci - HUMTHO1, TPOX, and CSF1PO - derived using multiplex PCR and manual typing

AU - Huang, Nu En

AU - Schumm, James

AU - Budowle, Bruce

PY - 1995/1/30

Y1 - 1995/1/30

N2 - Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.

AB - Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.

KW - Chinese

KW - Hardy-Weinberg expectations

KW - Linkage equilibrium

KW - PCR

KW - Polymerase chain reaction

KW - Population databases

KW - STR

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JO - Forensic Science International

JF - Forensic Science International

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ER -

Chinese population data on three tetrameric short tandem repeat loci - HUMTHO1, TPOX, and CSF1PO - derived using multiplex PCR and manual typing

Abstract

Keywords

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