Chinese population data on the PCR-based loci HLA-DQ alpha, low-density-lipoprotein receptor, Glycophorin A, Hemoglobin γG, D7S8, and group-specific component

Nu En Huang, Bruce Budowle

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Allele and genotype frequencies for six polymerase chain reaction (PCR)-based DNA genetic markers were determined in a Chinese sample population. The loci are HLA-DQα, low-density-lipoprotein receptor, glycophorin A, hemoglobin γG, D7S8, and group-specific component. These results were obtained using the AmpliType® HLA-DQα forensic DNA amplification and typing kit and the AmpliType PM PCR amplification and typing kit. All loci met Hardy-Weinberg expectations and there was no evidence for association of alleles between the loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Chinese population.

Original languageEnglish
Pages (from-to)34-40
Number of pages7
JournalHuman Heredity
Volume45
Issue number1
DOIs
StatePublished - 1 Jan 1995

Keywords

  • Chinese population databases
  • D7S8
  • Glycophorin A
  • Group-specific component
  • HLA-DQα
  • Hardy-Weinberg
  • Hemoglobin γ<sup>G</sup>
  • Low-density-lipoprotein receptor
  • Polymerase chain reaction

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