Research on age-related cognitive impairment is scarce in Central America. We report factors associated with cognitive impairment among a sample of older adults in Panama diagnosed with Alzheimer's disease (AD, n=31), mild cognitive impairment (MCI, n=43), or no cognitive impairment (controls, n=185). Apolipoprotein E (ApoE) genotype was assessed in a subset of cases (n=135). Age (OR=2.53, 95% CI=1.03-6.17) and ApoE ϵ4 (OR=5.14, 95% CI=2.11-12.52) were significantly related to cognitive impairment (AD/MCI combined). Results underscore the potential of genetic screening in Panama for identifying those at risk of dementia.
|Number of pages||5|
|Journal||Journal of Alzheimer's Disease|
|State||Published - 1 Jan 2016|
- Alzheimer's disease
- Latin America
- apolipoprotein E
- mild cognitive impairment