@article{63c873bab1cc4458a2d488672bd5b44d,
title = "Changes in inflammatory biomarkers following spinal manipulation",
author = "Licciardone, {John C.}",
note = "Funding Information: Kovanur-Sampath and colleagues (Kovanur-Sampath et?al., 2017) reviewed the literature on changes in biomarkers following spinal manipulation and called for trials targeting symptomatic populations to validate their findings. This letter describes findings of the OSTEOPATHIC Trial (Licciardone et?al., 2013), which was not included in their review. This was a randomized controlled trial of osteopathic manipulative treatment (OMT) vs. sham OMT in 455 patients with chronic low back pain. It was funded in part by the National Institutes of Health K24-AT002422 and registered with ClinicalTrials.gov. The trial supported the efficacy of OMT (including high-velocity, low amplitude thrust) based on 12-week outcomes for moderate and substantial improvements in pain intensity (Licciardone et?al., 2013) and recovery from chronic low back pain using a composite measure of pain and functioning (Licciardone et?al., 2016).",
year = "2017",
month = aug,
doi = "10.1016/j.msksp.2017.05.005",
language = "English",
volume = "30",
pages = "e91--e92",
journal = "Musculoskeletal Science and Practice",
issn = "2468-8630",
publisher = "Elsevier BV",
}