Catabolite repression of Escherichia coli biofilm formation

Debra W. Jackson, Jerry W. Simecka, Tony Romeo

Research output: Contribution to journalArticle

131 Scopus citations


Biofilm formation was repressed by glucose in several species of Enterobacteriaceae. In Escherichia coli, this effect was mediated at least in part by cyclic AMP (cAMP)-cAMP receptor protein. A temporal role for cAMP in biofilm development was indicated by the finding that glucose addition after ∼24 h failed to repress and generally activated biofilm formation.

Original languageEnglish
Pages (from-to)3406-3410
Number of pages5
JournalJournal of Bacteriology
Issue number12
StatePublished - 2002

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