Bone marrow stem cells: Source, characterization, isolation, culture, and identification

Chengcai Zheng, Yulei Zhou, Mengxiong Pan, Siyang Lin, Brian Wang, Kunlin Jin

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Stem cell transplantation offers an exciting new therapeutic avenue for stroke, as many studies have demonstrated favorable results in animal models with various cell types. Among them, the bone marrow stem cells (BMSCs) and mesenchymal stem cells (MSCs) in particular, may have enormous therapeutic potential because they can be harvested from the patients themselves without posing ethical or immunological difficulties. More importantly, BMSCs represent an important stem cell population with multipotent functions, including migration and transport functions to sites of local injuries or tissue damage to support appropriate cell and tissue renewal to replace the damaged areas, which are extremely useful for clinical applications, particularly in regenerative medicine. In this chapter, we summarize the source, characterization, isolation, culture, and identification of BMSCs.

Original languageEnglish
Title of host publicationBone Marrow Stem Cell Therapy for Stroke
PublisherSpringer Singapore
Number of pages17
ISBN (Electronic)9789811029295
ISBN (Print)9789811029288
StatePublished - 1 Jan 2016


  • Bone marrow stem cells
  • Characterization
  • Culture
  • Identification
  • Isolation


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