Bone marrow stem cells: Source, characterization, isolation, culture, and identification

Chengcai Zheng, Yulei Zhou, Mengxiong Pan, Siyang Lin, Brian Wang, Kunlin Jin

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Stem cell transplantation offers an exciting new therapeutic avenue for stroke, as many studies have demonstrated favorable results in animal models with various cell types. Among them, the bone marrow stem cells (BMSCs) and mesenchymal stem cells (MSCs) in particular, may have enormous therapeutic potential because they can be harvested from the patients themselves without posing ethical or immunological difficulties. More importantly, BMSCs represent an important stem cell population with multipotent functions, including migration and transport functions to sites of local injuries or tissue damage to support appropriate cell and tissue renewal to replace the damaged areas, which are extremely useful for clinical applications, particularly in regenerative medicine. In this chapter, we summarize the source, characterization, isolation, culture, and identification of BMSCs.

Original languageEnglish
Title of host publicationBone Marrow Stem Cell Therapy for Stroke
PublisherSpringer Singapore
Pages37-53
Number of pages17
ISBN (Electronic)9789811029295
ISBN (Print)9789811029288
DOIs
StatePublished - 1 Jan 2016

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Stem cells
Cell culture
Bone Marrow Cells
Bone
Stem Cells
Regenerative Medicine
Stem Cell Transplantation
Mesenchymal Stromal Cells
Tissue
Animal Models
Stroke
Wounds and Injuries
Animals
Therapeutics
Population

Keywords

  • Bone marrow stem cells
  • Characterization
  • Culture
  • Identification
  • Isolation

Cite this

Zheng, C., Zhou, Y., Pan, M., Lin, S., Wang, B., & Jin, K. (2016). Bone marrow stem cells: Source, characterization, isolation, culture, and identification. In Bone Marrow Stem Cell Therapy for Stroke (pp. 37-53). Springer Singapore. https://doi.org/10.1007/978-981-10-2929-5_2
Zheng, Chengcai ; Zhou, Yulei ; Pan, Mengxiong ; Lin, Siyang ; Wang, Brian ; Jin, Kunlin. / Bone marrow stem cells : Source, characterization, isolation, culture, and identification. Bone Marrow Stem Cell Therapy for Stroke. Springer Singapore, 2016. pp. 37-53
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Zheng, C, Zhou, Y, Pan, M, Lin, S, Wang, B & Jin, K 2016, Bone marrow stem cells: Source, characterization, isolation, culture, and identification. in Bone Marrow Stem Cell Therapy for Stroke. Springer Singapore, pp. 37-53. https://doi.org/10.1007/978-981-10-2929-5_2

Bone marrow stem cells : Source, characterization, isolation, culture, and identification. / Zheng, Chengcai; Zhou, Yulei; Pan, Mengxiong; Lin, Siyang; Wang, Brian; Jin, Kunlin.

Bone Marrow Stem Cell Therapy for Stroke. Springer Singapore, 2016. p. 37-53.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Zheng C, Zhou Y, Pan M, Lin S, Wang B, Jin K. Bone marrow stem cells: Source, characterization, isolation, culture, and identification. In Bone Marrow Stem Cell Therapy for Stroke. Springer Singapore. 2016. p. 37-53 https://doi.org/10.1007/978-981-10-2929-5_2