Asymmetric synthesis of anti-convulsive drug (S)-Vigabatrin®

S. Chandrasekhar, Suchismita Mohapatra

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

An asymmetric synthesis of fully protected (S)-Vigabatrin® is described using Sharpless asymmetric aminohydroxylation and reductive elimination of α-oxyβ-amino carbonylhydrazone as key steps.

Original languageEnglish
Pages (from-to)6415-6418
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number35
DOIs
StatePublished - 27 Aug 1998

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