Arab population data on the PCR-based loci: HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc, and D1S80

J. M. Hayes, Bruce Budowle, M. Freund

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Allele and genotype frequencies for seven polymerase chain reaction (PCR)- based DNA genetic markers were determined in an Arab sample population. The loci analyzed were HLA-DQAI, LDLR, GYPA, HBGG, D7S8, Gc and D1S80. Results were obtained from the first six loci using the AmpliType HLA-DQα DNA and AmpliType PM PCR Amplification and Typing Kits. The VNTR locus D1S80 PCR product was analyzed by polyacrylamide electrophoresis and silver staining. All loci meet Hardy-Weinberg expectations. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Arab population.

Original languageEnglish
Pages (from-to)888-892
Number of pages5
JournalJournal of forensic sciences
Volume40
Issue number5
StatePublished - 1 Jan 1995

Keywords

  • Arab
  • D1S80
  • D7S8
  • Gc
  • GYPA
  • Hardy-Weinberg
  • HBGG
  • HLA-DQA1
  • LDLR
  • pathology and biology
  • polymerase chain reaction
  • population databases

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