Application of a Brain-Targeting Chemical Delivery System to 9-Amino-1,2,3,4-Tetrahydroacridine

Keyphrases

• Brain Targeting 100%
• Amino 100%
• Chemical Delivery System 100%
• Quaternary Salts 100%
• Dihydroacridine 100%
• Central Nervous System 66%
• Acetylcholinesterase 33%
• Acetylcholinesterase Inhibitors (AChEI) 33%
• Pyridinium Salts 33%
• Sustained Release 33%
• Distribution Studies 33%
• In Vivo Distribution 33%
• Redox System 33%
• Pyridinium 33%
• 1,4-Dihydropyridines (1,4-DHPs) 33%
• Amino Group 33%
• Oxidation Studies 33%
• Acylation 33%
• Lipophilicity Determination 33%
• Lipophilic Index 33%
• Transport Forms 33%
• Amino Functionality 33%
• Anhydride 33%
• Stereoselective Reduction 33%
• Pyridine Ring 33%
• Selective N-alkylation 33%
• Ring Reduction 33%
• Forced Conditions 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Tacrine 100%
• Table Salt 100%
• Cholinesterase Inhibitor 50%
• Acetylcholinesterase 50%
• Pyridinium Derivative 50%
• Sustained Release 50%
• Lipophilicity 50%
• 1,4 Dihydropyridine 50%
• Acid Anhydride 50%