Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers

Lori A. Gordon, Parag Kumar, Kristina M. Brooks, Anela Kellogg, Maryellen McManus, Raul M. Alfaro, Khanh Nghiem, Jomy M. George, Jay Lozier, Scott R. Penzak, Colleen Hadigan

Research output: Contribution to journalArticlepeer-review

15 Scopus citations
Original languageEnglish
Pages (from-to)1909-1911
Number of pages3
JournalCirculation
Volume134
Issue number23
DOIs
StatePublished - 6 Dec 2016

Keywords

  • anticoagulants
  • antiretroviral
  • cobicistat
  • dabigatran
  • drug-drug interaction
  • pharmacodynamics
  • pharmacokinetics
  • thrombin time

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