Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers

Lori A. Gordon, Parag Kumar, Kristina M. Brooks, Anela Kellogg, Maryellen McManus, Raul M. Alfaro, Khanh Nghiem, Jomy M. George, Jay Lozier, Scott R. Penzak, Colleen Hadigan

Research output: Contribution to journal › Article

14 Citations (Scopus)
Original languageEnglish
Pages (from-to)1909-1911
Number of pages3
JournalCirculation
Volume134
Issue number23
DOIs
StatePublished - 6 Dec 2016

Keywords

  • anticoagulants
  • antiretroviral
  • cobicistat
  • dabigatran
  • drug-drug interaction
  • pharmacodynamics
  • pharmacokinetics
  • thrombin time

Cite this

Gordon, Lori A. ; Kumar, Parag ; Brooks, Kristina M. ; Kellogg, Anela ; McManus, Maryellen ; Alfaro, Raul M. ; Nghiem, Khanh ; George, Jomy M. ; Lozier, Jay ; Penzak, Scott R. ; Hadigan, Colleen. / Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers. In: Circulation. 2016 ; Vol. 134, No. 23. pp. 1909-1911.
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title = "Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers",
keywords = "anticoagulants, antiretroviral, cobicistat, dabigatran, drug-drug interaction, pharmacodynamics, pharmacokinetics, thrombin time",
author = "Gordon, {Lori A.} and Parag Kumar and Brooks, {Kristina M.} and Anela Kellogg and Maryellen McManus and Alfaro, {Raul M.} and Khanh Nghiem and George, {Jomy M.} and Jay Lozier and Penzak, {Scott R.} and Colleen Hadigan",
year = "2016",
month = "12",
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doi = "10.1161/CIRCULATIONAHA.116.025257",
language = "English",
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pages = "1909--1911",
journal = "Circulation",
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Gordon, LA, Kumar, P, Brooks, KM, Kellogg, A, McManus, M, Alfaro, RM, Nghiem, K, George, JM, Lozier, J, Penzak, SR & Hadigan, C 2016, 'Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers', Circulation, vol. 134, no. 23, pp. 1909-1911. https://doi.org/10.1161/CIRCULATIONAHA.116.025257

Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers. / Gordon, Lori A.; Kumar, Parag; Brooks, Kristina M.; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M.; Nghiem, Khanh; George, Jomy M.; Lozier, Jay; Penzak, Scott R.; Hadigan, Colleen.

In: Circulation, Vol. 134, No. 23, 06.12.2016, p. 1909-1911.

Research output: Contribution to journal › Article

TY - JOUR

T1 - Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers

AU - Gordon, Lori A.

AU - Kumar, Parag

AU - Brooks, Kristina M.

AU - Kellogg, Anela

AU - McManus, Maryellen

AU - Alfaro, Raul M.

AU - Nghiem, Khanh

AU - George, Jomy M.

AU - Lozier, Jay

AU - Penzak, Scott R.

AU - Hadigan, Colleen

PY - 2016/12/6

Y1 - 2016/12/6

KW - anticoagulants

KW - antiretroviral

KW - cobicistat

KW - dabigatran

KW - drug-drug interaction

KW - pharmacodynamics

KW - pharmacokinetics

KW - thrombin time

UR - http://www.scopus.com/inward/record.url?scp=85002905478&partnerID=8YFLogxK

U2 - 10.1161/CIRCULATIONAHA.116.025257

DO - 10.1161/CIRCULATIONAHA.116.025257

M3 - Article

AN - SCOPUS:85002905478

VL - 134

SP - 1909

EP - 1911

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 23

ER -

Gordon LA, Kumar P, Brooks KM, Kellogg A, McManus M, Alfaro RM et al. Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers. Circulation. 2016 Dec 6;134(23):1909-1911. https://doi.org/10.1161/CIRCULATIONAHA.116.025257

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