Analysis of the HUMTH01 allele frequencies in the Spanish population

J. A. Lorente, M. Lorente, B. Budowle, M. R. Wilson, E. Villanueva

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254/allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.

Original languageEnglish
Pages (from-to)1270-1274
Number of pages5
JournalJournal of Forensic Sciences
Volume39
Issue number5
DOIs
StatePublished - 1 Jan 1994

Keywords

  • DNA
  • HUMTH01
  • PCR
  • STR
  • forensic genetics
  • pathology and biology

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