Analysis of the HUMTH01 allele frequencies in the Spanish population

J. A. Lorente; M. Lorente; B. Budowle; M. R. Wilson; E. Villanueva

doi:10.1520/jfs13712j

Analysis of the HUMTH01 allele frequencies in the Spanish population

J. A. Lorente, M. Lorente, B. Budowle, M. R. Wilson, E. Villanueva

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13 Scopus citations

Abstract

Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254/allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.

Original language	English
Pages (from-to)	1270-1274
Number of pages	5
Journal	Journal of Forensic Sciences
Volume	39
Issue number	5
DOIs	https://doi.org/10.1520/jfs13712j
State	Published - 1 Jan 1994

Keywords

DNA
HUMTH01
PCR
STR
forensic genetics
pathology and biology

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10.1520/jfs13712j

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title = "Analysis of the HUMTH01 allele frequencies in the Spanish population",

abstract = "Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254/allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.",

keywords = "DNA, HUMTH01, PCR, STR, forensic genetics, pathology and biology",

author = "Lorente, {J. A.} and M. Lorente and B. Budowle and Wilson, {M. R.} and E. Villanueva",

year = "1994",

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T1 - Analysis of the HUMTH01 allele frequencies in the Spanish population

AU - Lorente, J. A.

AU - Lorente, M.

AU - Budowle, B.

AU - Wilson, M. R.

AU - Villanueva, E.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254/allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.

AB - Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254/allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.

KW - DNA

KW - HUMTH01

KW - PCR

KW - STR

KW - forensic genetics

KW - pathology and biology

UR - http://www.scopus.com/inward/record.url?scp=0028674481&partnerID=8YFLogxK

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SN - 0022-1198

VL - 39

SP - 1270

EP - 1274

JO - Journal of forensic sciences

JF - Journal of forensic sciences

IS - 5

ER -

Analysis of the HUMTH01 allele frequencies in the Spanish population

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Keywords

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