Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery

Bruce J. Melancon; Corey R. Hopkins; Michael R. Wood; Kyle A. Emmitte; Colleen M. Niswender; Arthur Christopoulos; P. Jeffrey Conn; Craig W. Lindsley

doi:10.1021/jm201139r

Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery

Bruce J. Melancon, Corey R. Hopkins, Michael R. Wood, Kyle A. Emmitte, Colleen M. Niswender, Arthur Christopoulos, P. Jeffrey Conn, Craig W. Lindsley

Research output: Contribution to journal › Review article › peer-review

198 Scopus citations

Original language	English
Pages (from-to)	1445-1464
Number of pages	20
Journal	Journal of Medicinal Chemistry
Volume	55
Issue number	4
DOIs	https://doi.org/10.1021/jm201139r
State	Published - 23 Feb 2012

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10.1021/jm201139r

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title = "Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery",

author = "Melancon, {Bruce J.} and Hopkins, {Corey R.} and Wood, {Michael R.} and Emmitte, {Kyle A.} and Niswender, {Colleen M.} and Arthur Christopoulos and Conn, {P. Jeffrey} and Lindsley, {Craig W.}",

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T2 - Theory, practice, and opportunities for central nervous system drug discovery

AU - Melancon, Bruce J.

AU - Hopkins, Corey R.

AU - Wood, Michael R.

AU - Emmitte, Kyle A.

AU - Niswender, Colleen M.

AU - Christopoulos, Arthur

AU - Conn, P. Jeffrey

AU - Lindsley, Craig W.

PY - 2012/2/23

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U2 - 10.1021/jm201139r

DO - 10.1021/jm201139r

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JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

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Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery

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