Abstract
Allosteric modulators allow for the fine-tuning of receptor responses to endogenous neurotransmitters and exogenous therapeutic agents. Different types of allosteric modulation of dopamine receptors are discussed as well as the significance of such modulation in the control of normal biological processes and in the treatment of disease.
| Original language | English |
|---|---|
| Pages (from-to) | 555-561 |
| Number of pages | 7 |
| Journal | Mini-Reviews in Medicinal Chemistry |
| Volume | 5 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2005 |
Keywords
- Biogenic amine
- Catecholamine
- Conformational change
- G protein-coupled receptor (GPCR)
- Metal
- Modulate
- Plateau
- Regulation
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Schetz, J. A. (2005). Allosteric modulation of dopamine receptors. Mini-Reviews in Medicinal Chemistry, 5(6), 555-561. https://doi.org/10.2174/1389557054023260