Allele frequencies of six miniSTR loci of three ethnic populations in Singapore

R. Y.Y. Yong; L. S.H. Gan; M. D. Coble; E. P.H. Yap

doi:10.1016/j.forsciint.2005.12.014

Allele frequencies of six miniSTR loci of three ethnic populations in Singapore

R. Y.Y. Yong, L. S.H. Gan, M. D. Coble, E. P.H. Yap

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. This study investigated the allele frequency of six miniSTR loci, D1S1677, D2S441, D4S2364, D10S1248, D14S1434 and D22S1045, in three Singapore populations. All loci showed a moderate degree of polymorphism with observed heterozygosity >0.6 for all three populations. The allele frequencies, forensic parameters and heterozygosity comparison with other CODIS STR in similar populations are presented.

Original language	English
Pages (from-to)	240-243
Number of pages	4
Journal	Forensic Science International
Volume	166
Issue number	2-3
DOIs	https://doi.org/10.1016/j.forsciint.2005.12.014
State	Published - 2 Mar 2007

Keywords

Allele frequencies
MiniSTR
Population data
Singapore

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10.1016/j.forsciint.2005.12.014

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abstract = "MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. This study investigated the allele frequency of six miniSTR loci, D1S1677, D2S441, D4S2364, D10S1248, D14S1434 and D22S1045, in three Singapore populations. All loci showed a moderate degree of polymorphism with observed heterozygosity >0.6 for all three populations. The allele frequencies, forensic parameters and heterozygosity comparison with other CODIS STR in similar populations are presented.",

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AU - Coble, M. D.

AU - Yap, E. P.H.

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AB - MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. This study investigated the allele frequency of six miniSTR loci, D1S1677, D2S441, D4S2364, D10S1248, D14S1434 and D22S1045, in three Singapore populations. All loci showed a moderate degree of polymorphism with observed heterozygosity >0.6 for all three populations. The allele frequencies, forensic parameters and heterozygosity comparison with other CODIS STR in similar populations are presented.

KW - Allele frequencies

KW - MiniSTR

KW - Population data

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ER -

Allele frequencies of six miniSTR loci of three ethnic populations in Singapore

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Keywords

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