[Aladan³]TIPP: A fluorescent δ-opioid antagonist with high δ-receptor binding affinity and δ selectivity

Keyphrases

• Receptor Binding Affinity 100%
• Opioid Antagonist 100%
• Binding Selectivity 100%
• Fluorescence Lifetime 50%
• Carbonyl Group 50%
• Fluorescence Quencher 50%
• Low Energy 50%
• Fluorophore 25%
• Highly Selective 25%
• Dimethylamino 25%
• Intracellular Distribution 25%
• Quantum Yield 25%
• Close Proximity 25%
• Lifetime Component 25%
• Side Chain 25%
• Membrane Interaction 25%
• Decay Measurements 25%
• Tissue Distribution 25%
• E-value 25%
• Receptor Binding Assay 25%
• Cellular Uptake 25%
• Fluorescence Emission 25%
• Aromatic-ring Stacking 25%
• Maximum Yield 25%
• Molecular Mechanics Calculations 25%
• Steady-state Fluorescence 25%
• Mouse Vas Deferens 25%
• Theoretical Conformational Analysis 25%
• Pharmacological Tools 25%
• Hydrophobic Interaction 25%
• Fluorescent Analog 25%
• Opioid Receptor Binding 25%
• Fluorescent Amino Acids 25%
• Environmental Sensitivity 25%

Chemistry

• Receptor Binding Affinity 100%
• Phe-Phe 100%
• Narcotic Antagonist 100%
• Conformational Isomer 33%
• Fluorescence Quencher 33%
• Carbonyl Group 33%
• Quantum Yield 16%
• Fluorescence Decay 16%
• Fluorescence Lifetime 16%
• Fluorescence Emission Maxima 16%
• Molecular Mechanics Calculation 16%
• Aromatic Structure 16%
• Inhibition Constant (Ki) 16%
• Statistical Ensemble 16%
• Amino Acid 16%
• Alanine 16%
• Subcellular Localization 16%

Biochemistry, Genetics and Molecular Biology

• Receptor Binding 100%
• Binding Affinity 100%
• Narcotic Antagonist 100%
• Subcellular Localization 25%
• Lifespan 25%
• Quantum Yield 25%
• Amino Acids 25%
• Steady State 25%
• Tissue Distribution 25%
• Molecular Mechanic 25%
• Opioid Receptor 25%
• Ligand Binding Assay 25%
• Alanine 25%