Agrobacterium radiobacter line infection: Case report and summary of in vitro susceptibility

Patrick G. Clay, R. Chris Rathbun

Research output: Contribution to journalArticle

Abstract

Agrobacterium radiobacter (A. radiobacter) is an aerobic, gram-negative bacillus that is an uncommon cause of disease but has been increasingly associated with catheter related infections in immunocompromised patients. Definitive information regarding effective treatment strategies is currently lacking; however, many A. radiobacter isolates are only susceptible to broad- spectrum antibiotics. We report a patient with A. radiobacter catheter infection who failed to improve on antibiotic therapy that displayed in vitro activity but did improve upon removal of the catheter and hub. Summaries of published case reports and susceptibility results are presented along with a discussion of empiric treatment strategies. Irrespective of the role of catheter removal, use of either imipenem/cilastatin or a quinolone appears appropriate based on literature reports and susceptibility data accumulated to date.

Original languageEnglish
Pages (from-to)7-16
Number of pages10
JournalJournal of Infectious Disease Pharmacotherapy
Volume4
Issue number1
DOIs
StatePublished - 1999

Keywords

  • Agrobacterium radiobacter
  • Case report
  • Catheter-infection
  • Drugs of choice
  • Literature-summary
  • Multidrug- resistant bacteria
  • Treatment guidelines

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