TY - JOUR
T1 - African origin of modern humans in East Asia
T2 - A tale of 12,000 Y chromosomes
AU - Ke, Yuehai
AU - Su, Bing
AU - Song, Xiufeng
AU - Lu, Daru
AU - Chen, Lifeng
AU - Li, Hongyu
AU - Qi, Chunjian
AU - Marzuki, Sangkot
AU - Deka, Ranjan
AU - Underhill, Peter
AU - Xiao, Chunjie
AU - Shriver, Mark
AU - Lell, Jeff
AU - Wallace, Douglas
AU - Wells, R. Spencer
AU - Seielstad, Mark
AU - Oefner, Peter
AU - Zhu, Dingliang
AU - Jin, Jianzhong
AU - Huang, Wei
AU - Chakraborty, Ranajit
AU - Chen, Zhu
AU - Jin, Li
PY - 2001/5/11
Y1 - 2001/5/11
N2 - To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.
AB - To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.
UR - http://www.scopus.com/inward/record.url?scp=0035844029&partnerID=8YFLogxK
U2 - 10.1126/science.1060011
DO - 10.1126/science.1060011
M3 - Article
C2 - 11349147
AN - SCOPUS:0035844029
SN - 0036-8075
VL - 292
SP - 1151
EP - 1153
JO - Science
JF - Science
IS - 5519
ER -