Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

William H. Cooke, Anusheela Pokhrel, Colin Dowling, Donovan L. Fogt, Caroline Alice Rickards

Research output: Contribution to journalArticle

11 Scopus citations


Purpose: Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown. Methods: Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized). Results: Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control. Conclusions: Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.

Original languageEnglish
Pages (from-to)267-270
Number of pages4
JournalClinical Autonomic Research
Issue number4
StatePublished - 22 Aug 2015



  • Autonomic control
  • Blood pressure
  • Electronic cigarettes
  • Head-up tilt

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