Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

William H. Cooke; Anusheela Pokhrel; Colin Dowling; Donovan L. Fogt; Caroline A. Rickards

doi:10.1007/s10286-015-0304-z

Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

William H. Cooke, Anusheela Pokhrel, Colin Dowling, Donovan L. Fogt, Caroline A. Rickards

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Purpose: Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown. Methods: Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized). Results: Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control. Conclusions: Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.

Original language	English
Pages (from-to)	267-270
Number of pages	4
Journal	Clinical Autonomic Research
Volume	25
Issue number	4
DOIs	https://doi.org/10.1007/s10286-015-0304-z
State	Published - 22 Aug 2015

Keywords

Autonomic control
Blood pressure
Electronic cigarettes
Head-up tilt

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10.1007/s10286-015-0304-z

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title = "Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study",

abstract = "Purpose: Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown. Methods: Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized). Results: Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control. Conclusions: Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.",

keywords = "Autonomic control, Blood pressure, Electronic cigarettes, Head-up tilt",

author = "Cooke, {William H.} and Anusheela Pokhrel and Colin Dowling and Fogt, {Donovan L.} and Rickards, {Caroline A.}",

note = "Funding Information: This study was supported by a Collaborative Seed Grant through the Office of the Vice President for Research, University of Texas at San Antonio, San Antonio Texas. We appreciate the technical assistance of Ms. Audrey Ramirez. Publisher Copyright: {\textcopyright} 2015, Springer-Verlag Berlin Heidelberg.",

year = "2015",

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doi = "10.1007/s10286-015-0304-z",

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T1 - Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers

T2 - a pilot study

AU - Cooke, William H.

AU - Pokhrel, Anusheela

AU - Dowling, Colin

AU - Fogt, Donovan L.

AU - Rickards, Caroline A.

N1 - Funding Information: This study was supported by a Collaborative Seed Grant through the Office of the Vice President for Research, University of Texas at San Antonio, San Antonio Texas. We appreciate the technical assistance of Ms. Audrey Ramirez. Publisher Copyright: © 2015, Springer-Verlag Berlin Heidelberg.

PY - 2015/8/22

Y1 - 2015/8/22

N2 - Purpose: Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown. Methods: Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized). Results: Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control. Conclusions: Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.

AB - Purpose: Electronic cigarettes are growing in popularity, but the physiological consequences of vaporized nicotine are unknown. Methods: Twenty healthy non-smokers inhaled vaporized nicotine and placebo (randomized). Results: Nicotine inhalation was associated with higher arterial pressures in the seated position, and increased arterial pressures in the head-up positions with no other effects on autonomic control. Conclusions: Our results show that vaporized nicotine inhalation is not innocuous. Longitudinal studies in otherwise healthy non-smokers should be conducted.

KW - Autonomic control

KW - Blood pressure

KW - Electronic cigarettes

KW - Head-up tilt

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ER -

Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

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