Activation of phospholipase C and guanylyl cyclase by endothelins in human trabecular meshwork cells

Keyphrases

• Trabecular Meshwork Cells 100%
• Phospholipase C 100%
• Endothelin-1 (ET-1) 100%
• Guanylate Cyclase 100%
• Receptor Subtypes 37%
• ETA Receptor 37%
• Sarafotoxins 37%
• ETB Receptor 25%
• EC50 25%
• Receptor Antagonist 12%
• Cyclic Adenosine Monophosphate (cAMP) 12%
• Dose Effect 12%
• Inositol Phosphate 12%
• Human Trabecular Meshwork 12%
• Selective Antagonist 12%
• High Concentration 12%
• Concentration-dependent 12%
• Cell Lysate 12%
• Cyclic GMP 12%
• Phospholipase C Activity 12%
• Radioimmunoassay 12%
• BQ-788 12%
• Receptor Agonist 12%
• Adenylyl Cyclase Activity 12%
• Subtype-specific 12%
• Simian Virus 40 (SV40) 12%
• IOP-lowering Effect 12%
• Pre-treating 12%
• Subtype-selective Agonist 12%
• Nucleotide Cyclase 12%
• Cyclic GMP-AMP 12%
• BQ123 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Endothelin 100%
• Guanylate Cyclase 100%
• Lecithinase 100%
• Endothelin 1 85%
• Receptor Subtype 42%
• Sarafotoxin S6c 42%
• Cyclic GMP 28%
• EC50 28%
• Receptor 14%
• Inositol Phosphate 14%
• Cyclic AMP 14%
• Adenylate Cyclase 14%
• Radioimmunoassay 14%
• Receptor Agonist 14%
• Simian Virus 40 14%
• Receptor Antagonist 14%

Biochemistry, Genetics and Molecular Biology

• Guanylate Cyclase 100%
• Endothelin 100%
• Lecithinase 100%
• Endothelin 1 85%
• Cyclic Guanosine Monophosphate 28%
• EC50 28%
• Receptor Antagonist 14%
• Agonist 14%
• Cyclic Adenosine Monophosphate 14%
• Cell Lysate 14%
• Receptor Agonists 14%
• Adenylate Cyclase 14%
• Simian Virus 40 14%
• Cyclase 14%
• BQ-123 14%
• Inositol Phosphate 14%