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Activation of mTOR: A culprit of Alzheimer’s disease?
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Keyphrases
3′-AMP
14%
Alzheimer's Disease
100%
AMP-activated Protein Kinase
14%
Amyloid Plaques
14%
Amyloid Precursor Protein
14%
Autophagy
42%
Clinical Presentation
14%
Cognitive Impairment
28%
Glycogen Synthase Kinase 3 (GSK3)
14%
Growth Factors
14%
Insulin
14%
Insulin-like
14%
Mammalian Target of Rapamycin (mTOR)
100%
Mammalian Target of Rapamycin Signaling
14%
Neurofibrillary Tangles
14%
Phosphorylated tau
14%
Protein Kinase B
14%
Protein Kinase B/Akt
14%
Protein Metabolism
14%
Rapamycin
14%
Scissors
14%
Secretase
14%
Signaling Pathway
14%
Tau Hyperphosphorylation
14%
Therapeutic Target
14%
Medicine and Dentistry
Alzheimer's Disease
100%
Amyloid Plaque
12%
Amyloid Precursor Protein
12%
Amyloid Protein
12%
Autophagy
37%
Cognitive Defect
25%
Glycogen Synthase Kinase 3
12%
Hydroxymethylglutaryl Coenzyme A Reductase Kinase
12%
Hyperphosphorylation
12%
Mechanistic Target of Rapamycin
100%
Neurofibrillary Tangle
12%
Phosphoinositide 3-Kinase
12%
Protein Kinase B
12%
Protein Metabolism
12%
Rapamycin
12%
Secretase
12%
Signal Transduction
12%
Somatomedin C
12%
Tau
25%
Neuroscience
Alzheimer's Disease
100%
AMP-activated Protein Kinase
12%
Amyloid Precursor Protein
12%
Amyloid Protein
25%
Autophagy
37%
Cell Signaling
12%
Cognitive Disorders
25%
Glycogen Synthase Kinase 3
12%
Hyperphosphorylation
12%
Insulin-Like Growth Factor 1
12%
Mammalian Target of Rapamycin
100%
Metabolic Pathway
12%
Phosphoinositide 3-Kinase
12%
Protein Kinase B
12%
Secretase
12%
Sirolimus
12%
Pharmacology, Toxicology and Pharmaceutical Science
Alzheimer's Disease
100%
Amyloid Plaque
12%
Amyloid Precursor Protein
12%
Amyloid Protein
12%
Cognitive Defect
25%
Glycogen Synthase Kinase 3
12%
Hydroxymethylglutaryl Coenzyme A Reductase Kinase
12%
Mammalian Target of Rapamycin
100%
Neurofibrillary Tangle
12%
Phosphatidylinositol 3 Kinase
12%
Protein Kinase B
12%
Rapamycin
12%
Secretase
12%
Somatomedin C
12%
Biochemistry, Genetics and Molecular Biology
AMP-activated Protein Kinase
12%
Amyloid Precursor Protein
12%
Amyloid Protein
25%
Autophagy
37%
Glycogen Synthase Kinase 3
12%
Hyperphosphorylation
12%
Insulin-Like Growth Factor 1
12%
Mechanistic Target of Rapamycin
100%
Neurofibrillary Tangle
12%
Phosphoinositide 3-Kinase
12%
Protein Kinase B
12%
Protein Metabolism
12%
Secretase
12%
Signal Transduction
12%
Tau
25%