Activation of ERK during DNA damage-induced apoptosis involves protein kinase Cδ

Medicine & Life Sciences

• Extracellular Signal-Regulated MAP Kinases 100%
• Protein Kinase C 87%
• Cisplatin 83%
• DNA Damage 80%
• Apoptosis 56%
• rottlerin 35%
• U 0126 28%
• Protein C Inhibitor 27%
• Mitogen-Activated Protein Kinase Kinases 25%
• Protein Kinase Inhibitors 24%
• HeLa Cells 22%
• bisindolylmaleimide 17%
• Caspases 11%
• Small Interfering RNA 9%
• Cell Death 8%
• Phosphorylation 7%

Chemical Compounds

• U0126 59%
• Rottlerin 59%
• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 49%
• Protein Kinase C Inhibitor 48%
• Protein 38%
• Cisplatin 33%
• Silencing RNA 19%
• Cell Death 16%
• Resistance 9%