TY - JOUR
T1 - A population genetic study in the Ochamchir Region, Abkhazia, SSR
AU - Ferrell, Robert E.
AU - Salamatina, Naira V.
AU - Dalakishvili, S. M.
AU - Bakuradze, N. A.
AU - Chakraborty, Ranajit
PY - 1985/1
Y1 - 1985/1
N2 - The reported longevity of residents of the Soviet Socialist Republic of the Caucasus has focused considerable attention on this population. However, little is known of the genetic composition of this population. With this in mind, several village populations of the Ochamchir Region, Abkhazia, SSR, were typed for 37 discrete genetic blood groups, erythrocyte and plasma protein loci. Gene and haplotype frequencies calculated for the polymorphic markers were determined and the results used in an analysis of intervillage heterogeneity and genetic distance analysis comparing the Abkhazians to European and Asian reference populations. The Abkhazians are approximately equal distance from European and West Asian populations in a genetic sense, and this is consistent with their geographical location. In addition to the usual genetic polymorphisms, rare electrophoretic variants were encountered at the lactate dehydrogenase A and phosphohexose isomerase loci. These results suggest that the population of the Ochamchir Region is relatively homogeneous and not distinctly different from its geographical neighbors.
AB - The reported longevity of residents of the Soviet Socialist Republic of the Caucasus has focused considerable attention on this population. However, little is known of the genetic composition of this population. With this in mind, several village populations of the Ochamchir Region, Abkhazia, SSR, were typed for 37 discrete genetic blood groups, erythrocyte and plasma protein loci. Gene and haplotype frequencies calculated for the polymorphic markers were determined and the results used in an analysis of intervillage heterogeneity and genetic distance analysis comparing the Abkhazians to European and Asian reference populations. The Abkhazians are approximately equal distance from European and West Asian populations in a genetic sense, and this is consistent with their geographical location. In addition to the usual genetic polymorphisms, rare electrophoretic variants were encountered at the lactate dehydrogenase A and phosphohexose isomerase loci. These results suggest that the population of the Ochamchir Region is relatively homogeneous and not distinctly different from its geographical neighbors.
KW - Abkhazia
KW - Genetic distance
KW - Genetic polymorphism
KW - Population genetics
UR - http://www.scopus.com/inward/record.url?scp=0021939588&partnerID=8YFLogxK
U2 - 10.1002/ajpa.1330660106
DO - 10.1002/ajpa.1330660106
M3 - Article
C2 - 3976871
AN - SCOPUS:0021939588
SN - 0002-9483
VL - 66
SP - 63
EP - 71
JO - American Journal of Physical Anthropology
JF - American Journal of Physical Anthropology
IS - 1
ER -