A point mutation to Gα_i selectively blocks GoLoco motif binding: Direct evidence for Gα·GoLoco complexes in mitotic spindle dynamics

Keyphrases

• Adenylyl Cyclase 50%
• Asparagine 50%
• Asymmetric Cell Division 50%
• Biochemical Properties 50%
• Caenorhabditis Elegans 50%
• Cell Division 100%
• Chromosomal Segregation 50%
• Conserved Set 50%
• Ectopic Expression 50%
• Epithelial Progenitors 50%
• Functional Role 50%
• G Protein 50%
• GPSM2 50%
• GTP Hydrolysis 50%
• Helical Domain 50%
• Intrinsic Protein 50%
• Invertebrates 50%
• Kidney Epithelial Cells 50%
• Leucine 50%
• Loss Function 50%
• Microtubule Dynamics 100%
• Mitotic Spindle 100%
• Neuroepithelium 50%
• Nucleotide-binding Protein 50%
• Physiological Role 50%
• Plasma Membrane 50%
• Point mutation 100%
• Protein Complex 100%
• Receptor-mediated 50%
• Regulatory Proteins 50%
• RGS Proteins 50%
• Seven-transmembrane Receptor 50%
• Signal Properties 50%
• Signal Transduction 50%
• Spindle Dynamics 100%
• Spindle Microtubules 50%
• Spindle Orientation 50%
• Vertebrates 50%

Biochemistry, Genetics and Molecular Biology

• Adenylate Cyclase 12%
• Asparagine 12%
• Asymmetric Cell Division 12%
• Binding Protein 12%
• Caenorhabditis Elegans 12%
• Cell Division 25%
• Cell Membrane 12%
• Chromosome Segregation 12%
• Dynamics 100%
• Ectopic Expression 12%
• Eicosanoid Receptor 12%
• Enzymatic Hydrolysis 12%
• GoLoco Motif 100%
• Guanosine Triphosphate 12%
• Heterotrimeric G Protein 12%
• Isoleucine 12%
• Metaphase 12%
• Mitosis Spindle 100%
• Point Mutation 100%
• Protein Complexes 25%
• Protein G 12%
• Protein Motif 50%
• Regulator of G Protein Signalling 12%
• Signal Transduction 12%
• Transmembrane Domain 12%
• Wild Type 12%