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2020

Metformin and cognition from the perspectives of sex, age, and disease

Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Jan 2020, (Accepted/In press) In : GeroScience.

Research output: Contribution to journalReview article

Metformin
Cognition
Hyperglycemia
Precision Medicine
Type 2 Diabetes Mellitus
2019
1 Citation (Scopus)

A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

Research output: Contribution to journalArticle

Astrocytes
Phenotype
Serum
Fibroblast Growth Factor 2
Epidermal Growth Factor

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

Research output: Contribution to journalArticle

Astrocytes
Oxidative Stress
Neuroprotective Agents
Energy Metabolism
Glutamic Acid
6 Citations (Scopus)

Experimental ischemic stroke induces long-term T cell activation in the brain

Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S. H., 1 Nov 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 11, p. 2268-2276 9 p.

Research output: Contribution to journalArticle

Stroke
T-Lymphocytes
Brain
Perforin
Interleukin-17
1 Citation (Scopus)

Metformin alters locomotor and cognitive function and brain metabolism in normoglycemic mice

Li, W., Chaudhari, K., Shetty, R., Winters, A., Gao, X., Hu, Z., Ge, W. P., Sumien, N., Forster, M., Liu, R. & Yang, S. H., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 949-963 15 p.

Research output: Contribution to journalArticle

Open Access
Metformin
Cognition
Brain
Energy Metabolism
Glycerolphosphate Dehydrogenase
2018
2 Citations (Scopus)

Aging health and R & D for healthy longevity must be included into the WHO work program

Stambler, I., Jin, K., Lederman, S., Barzilai, N., Jay Olshansky, S., Omokaro, E., Barratt, J., Anisimov, V. N., Rattan, S., Yang, S., Forster, M. & Byles, J., 1 Apr 2018, In : Aging and Disease. 9, 2, p. 331-333 3 p.

Research output: Contribution to journalEditorial

Health
6 Citations (Scopus)

Artemisinin prevents glutamate-induced neuronal cell death via Akt pathway activation

Lin, S. P., Li, W., Winters, A., Liu, R. & Yang, S. H., 20 Apr 2018, In : Frontiers in Cellular Neuroscience. 12, 108.

Research output: Contribution to journalArticle

Glutamic Acid
Cell Death
artemisinine
Mitochondrial Membrane Potential
Antimalarials
1 Citation (Scopus)

Glia–immune interactions post-ischemic stroke and potential therapies

Hersh, J. & Yang, S. H., 1 Dec 2018, In : Experimental Biology and Medicine. 243, 17-18, p. 1302-1312 11 p.

Research output: Contribution to journalReview article

Immune system
Brain
Neuroglia
Stroke
Immune System
6 Citations (Scopus)

High-Throughput data of circular RNA profiles in human temporal cortex tissue reveals novel insights into temporal lobe epilepsy

Li, J., Lin, H., Sun, Z., Kong, G., Yan, X., Wang, Y., Wang, X., Wen, Y., Liu, X., Zheng, H., Jia, M., Shi, Z., Xu, R., Yang, S. & Yuan, F., Feb 2018, In : Cellular Physiology and Biochemistry. 45, 2, p. 677-691 15 p.

Research output: Contribution to journalArticle

Temporal Lobe Epilepsy
Temporal Lobe
Epilepsy
circular RNA
Long Noncoding RNA
3 Citations (Scopus)

Hyperglycemia alters astrocyte metabolism and inhibits astrocyte proliferation

Li, W., Choudhury, G. R., Winters, A., Prah, J., Lin, W., Liu, R. & Yang, S. H., 1 Jan 2018, In : Aging and Disease. 9, 4, p. 674-684 11 p.

Research output: Contribution to journalArticle

Astrocytes
Hyperglycemia
Glucose
Energy Metabolism
Cyclin D3
4 Citations (Scopus)

Insulin and heparin-binding epidermal growth factor-like growth factor synergistically promote astrocyte survival and proliferation in serum-free medium

Jia, M., Shi, Z., Yan, X., Xu, L., Dong, L., Li, J., Wang, Y., Yang, S. & Yuan, F., 1 Sep 2018, In : Journal of Neuroscience Methods. 307, p. 240-247 8 p.

Research output: Contribution to journalArticle

Serum-Free Culture Media
Epidermal Growth Factor
Astrocytes
Heparin
Intercellular Signaling Peptides and Proteins
2 Citations (Scopus)

Precision Medicine for Ischemic Stroke, Let Us Move Beyond Time Is Brain

Yang, S. H., Lou, M., Luo, B., Jiang, W. J. & Liu, R., 1 Apr 2018, In : Translational Stroke Research. 9, 2, p. 93-95 3 p.

Research output: Contribution to journalEditorial

Precision Medicine
Stroke
Brain
1 Citation (Scopus)

Surgical management of giant intrapetrous internal carotid aneurysm presenting with coil exposure after endovascular treatment

Yu, L. B., Zhang, D., Yang, S. H. & Zhao, J. Z., 1 Jul 2018, In : Neurosurgical Review. 41, 3, p. 891-894 4 p.

Research output: Contribution to journalArticle

Aneurysm
Otoscopes
Therapeutics
Digital Subtraction Angiography
Referral and Consultation
2017
5 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Ischemic Preconditioning
Stroke
Wounds and Injuries
5-methoxyindole-2-carboxylic acid
19 Citations (Scopus)
Methylene Blue
Neurodegenerative Diseases
Electrons
Energy Metabolism
Oxidative Phosphorylation
12 Citations (Scopus)

Aquaporin 4-mediated glutamate-induced astrocyte swelling is partially mediated through metabotropic glutamate receptor 5 activation

Shi, Z., Zhang, W., Lu, Y., Lu, Y., Xu, L., Fang, Q., Wu, M., Jia, M., Wang, Y., Dong, L., Yan, X., Yang, S. & Yuan, F., 28 Apr 2017, In : Frontiers in Cellular Neuroscience. 11, 116.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Aquaporin 4
Astrocytes
Glutamic Acid
Brain Edema
2 Citations (Scopus)

Cerebral Autoregulation

Yang, S. & Liu, R., 7 Mar 2017, Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc., p. 57-60 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Homeostasis
Cerebrovascular Circulation
Arterial Pressure
Blood Pressure
Brain
11 Citations (Scopus)

Combining injectable plasma scaffold with mesenchymal stem/stromal cells for repairing infarct cavity after ischemic stroke

Zhang, H., Sun, F., Wang, J., Xie, L., Pan, M., Shao, B., Yang, G. Y., Yang, S. H., ZhuGe, Q. & Jin, K., 1 Jan 2017, In : Aging and Disease. 8, 2, p. 203-214 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stroke
Injections
Neural Stem Cells
Brain
11 Citations (Scopus)

Control of cerebral ischemia with magnetic nanoparticles

Jia, J. M., Chowdary, P. D., Gao, X., Ci, B., Li, W., Mulgaonkar, A., Plautz, E. J., Hassan, G., Kumar, A., Stowe, A. M., Yang, S. H., Zhou, W., Sun, X., Cui, B. & Ge, W. P., 1 Feb 2017, In : Nature Methods. 14, 2, p. 160-166 7 p.

Research output: Contribution to journalArticle

Brain Ischemia
Nanoparticles
Blood
Ischemia
Microcirculation
10 Citations (Scopus)

Glutamate Impairs Mitochondria Aerobic Respiration Capacity and Enhances Glycolysis in Cultured Rat Astrocytes

YAN, X., SHI, Z. F., XU, L. X., LI, J. X., WU, M., WANG, X. X., JIA, M., DONG, L. P., YANG, S. H. & YUAN, F., 1 Jan 2017, In : Biomedical and Environmental Sciences. 30, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Glycolysis
Astrocytes
Glutamic Acid
Mitochondria
Respiration

Methylene blue inhibits GABAA receptors by interaction with GABA binding site

Chen, Z., Liu, R., Yang, S. H., Dillon, G. H. & Huang, R., 1 Jun 2017, In : Neuropharmacology. 119, p. 100-110 11 p.

Research output: Contribution to journalArticle

Methylene Blue
GABA-A Receptors
gamma-Aminobutyric Acid
Binding Sites
Picrotoxin
2016
9 Citations (Scopus)

Brain globins in physiology and pathology

Xie, L. K. & Yang, S. H., 1 Jul 2016, In : Medical Gas Research. 6, 3, p. 154-163 10 p.

Research output: Contribution to journalReview article

Globins
Pathology
Nervous System Diseases
Brain
Myoglobin
1 Citation (Scopus)

For the pursuit of oxygen and carbon dioxide channels in mitochondria

Yang, S. H. & Liu, R., 1 Oct 2016, In : Medical Gas Research. 6, 4, p. 237-238 2 p.

Research output: Contribution to journalEditorial

Carbon Dioxide
Mitochondria
Oxygen
13 Citations (Scopus)

Heat Shock Protein 47 Promotes Glioma Angiogenesis

Wu, Z. B., Cai, L., Lin, S. J., Leng, Z. G., Guo, Y. H., Yang, W. L., Chu, Y. W., Yang, S. H. & Zhao, W. G., 1 Jan 2016, In : Brain Pathology. 26, 1, p. 31-42 12 p.

Research output: Contribution to journalArticle

HSP47 Heat-Shock Proteins
Glioma
Human Umbilical Vein Endothelial Cells
Microvessels
Tumor Burden
9 Citations (Scopus)

Methylene blue ameliorates ischemia/reperfusion-induced cerebral edema: An MRI and transmission electron microscope study

Fang, Q., Yan, X., Li, S., Sun, Y., Xu, L., Shi, Z., Wu, M., Lu, Y., Dong, L., Liu, R., Yuan, F. & Yang, S. H., 1 Jan 2016, Acta Neurochirurgica, Supplementum. Springer-Verlag Wien, p. 227-236 10 p. (Acta Neurochirurgica, Supplementum; vol. 121).

Research output: Chapter in Book/Report/Conference proceedingChapter

Methylene Blue
Middle Cerebral Artery Infarction
Transient Ischemic Attack
Brain Edema
Neuroprotective Agents
9 Citations (Scopus)

Neuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism

Cai, B., Li, W., Mao, X. O., Winters, A., Ryou, M. G., Liu, R., Greenberg, D. A., Wang, N., Jin, K. & Yang, S. H., 1 Mar 2016, In : Molecular Neurobiology. 53, 2, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Glycogen
Globins
Neurons
Brain