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2020

Neuroprotection of Cyperus esculentus L. orientin against cerebral ischemia/reperfusion induced brain injury

Jing, S. Q., Wang, S. S., Zhong, R. M., Zhang, J. Y., Wu, J. Z., Tu, Y. X., Pu, Y. & Yan, L. J., 1 Mar 2020, In : Neural Regeneration Research. 15, 3, p. 548-556 9 p.

Research output: Contribution to journalArticle

Open Access
Cyperus
Brain Ischemia
Brain Injuries
Reperfusion
Reperfusion Injury

Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity

Yang, X., Sun, X., Wu, J., Ma, J., Si, P., Yin, L., Zhang, Y., Yan, L. J. & Zhang, C., 1 Apr 2020, In : Toxicology Letters. 322, p. 66-76 11 p.

Research output: Contribution to journalArticle

N-Methylaspartate
Phosphorylation
Serine
Cells
Messenger RNA
2019

Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress

Yang, X., Song, J. & Yan, L. J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.

Research output: Contribution to journalArticle

Open Access
Dihydrolipoamide Dehydrogenase
Oxidative stress
Oxidative Stress
Medical problems
Type 2 Diabetes Mellitus

Role of Catalase in Oxidative Stress- And Age-Associated Degenerative Diseases

Nandi, A., Yan, L. J., Jana, C. K. & Das, N., 1 Jan 2019, In : Oxidative Medicine and Cellular Longevity. 2019, 9613090.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Catalase
Oxidative Stress
Vitiligo
Antioxidants
3 Citations (Scopus)
Open Access
Fructose
Liver
Insulin Resistance
Obesity
Eating
2018
9 Citations (Scopus)

Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease

Zhao, Y. S., Zhang, L. H., Yu, P. P., Gou, Y. J., Zhao, J., You, L. H., Wang, Z. Y., Zheng, X., Yan, L. J., Yu, P. & Chang, Y. Z., 10 May 2018, In : Antioxidants and Redox Signaling. 28, 14, p. 1323-1337 15 p.

Research output: Contribution to journalArticle

Ceruloplasmin
Alzheimer Disease
Therapeutics
Iron
Hippocampus
5 Citations (Scopus)

Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway

Yang, X., Zhang, H., Wu, J., Yin, L., Yan, L. J. & Zhang, C., Oct 2018, In : International journal of molecular sciences. 19, 10, 2982.

Research output: Contribution to journalArticle

aspartates
JNK Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
N-Methylaspartate
Reactive Oxygen Species
6 Citations (Scopus)
Oxidative stress
Reperfusion
Oxidative Stress
Stroke
Wounds and Injuries
1 Citation (Scopus)
Hypoglycemic Agents
Dihydrolipoamide Dehydrogenase
Glucose
Gluconeogenesis
Cricetulus
11 Citations (Scopus)

Role and possible mechanisms of sirt1 in depression

Lu, G., Li, J., Zhang, H., Zhao, X., Yan, L. J. & Yang, X., 1 Jan 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 8596903.

Research output: Contribution to journalReview article

Sirtuin 1
Plague
Neurogenesis
Gene Silencing
Neuroglia
2017
5 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Ischemic Preconditioning
Stroke
Wounds and Injuries
5-methoxyindole-2-carboxylic acid
4 Citations (Scopus)

Non-gradient blue native polyacrylamide gel electrophoresis

Luo, X., Wu, J., Jin, Z. & Yan, L. J., 1 Feb 2017, In : Current Protocols in Protein Science. 2017, p. 19.29.1-19.29.12

Research output: Contribution to journalArticle

Native Polyacrylamide Gel Electrophoresis
Electrophoresis
Proteins
Esterases
Dihydrolipoamide Dehydrogenase
8 Citations (Scopus)

Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes

Wu, J., Luo, X., Thangthaeng, N., Sumien, N., Chen, Z., Rutledge, M. A., Jing, S., Forster, M. J. & Yan, L-J., 1 Sep 2017, In : Biochemistry and Biophysics Reports. 11, p. 119-129 11 p.

Research output: Contribution to journalArticle

Medical problems
NAD
Oxidative stress
Pancreas
Reactive Oxygen Species
12 Citations (Scopus)

Potential biochemical mechanisms of lung injury in diabetes

Zheng, H., Wu, J., Jin, Z. & Yan, L. J., 1 Jan 2017, In : Aging and Disease. 8, 1, p. 7-16 10 p.

Research output: Contribution to journalReview article

Lung Injury
Lung
Proto-Oncogene Proteins c-akt
Glycosylation
Type 2 Diabetes Mellitus
17 Citations (Scopus)

Redox imbalance and mitochondrial abnormalities in the diabetic lung

Wu, J., Jin, Z. & Yan, L. J., 1 Apr 2017, In : Redox Biology. 11, p. 51-59 9 p.

Research output: Contribution to journalArticle

NAD
Oxidation-Reduction
Medical problems
Oxidative stress
Lung
9 Citations (Scopus)

The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity

Yang, X., Si, P., Qin, H., Yin, L., Yan, L. J. & Zhang, C., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 2823454.

Research output: Contribution to journalArticle

Neuroprotective Agents
N-Methylaspartate
Acetylation
L-Lactate Dehydrogenase
Neurons
2016
14 Citations (Scopus)

Chemical conditioning as an approach to ischemic stroke tolerance: Mitochondria as the target

Jin, Z., Wu, J. & Yan, L. J., 8 Mar 2016, In : International journal of molecular sciences. 17, 3, 351.

Research output: Contribution to journalReview article

Mitochondria
mitochondria
conditioning
strokes
Stroke

Chronic mTOR Inhibition by Rapamycin and Diabetes: What is the Role of Mitochondria?

Yan, L. J. & Cai, Z., 26 Feb 2016, Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies. Elsevier Inc., p. 365-378 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sirolimus
Mitochondria
NAD
Oxidation-Reduction
Poly Adenosine Diphosphate Ribose
4 Citations (Scopus)
Chrysanthemum
Column chromatography
Polysaccharides
Chromatography
Antioxidants
14 Citations (Scopus)

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes

Dong, K., Wu, M., Liu, X., Huang, Y., Zhang, D., Wang, Y., Yan, L-J. & Shi, D., 1 Dec 2016, In : Free Radical Biology and Medicine. 101, p. 334-347 14 p.

Research output: Contribution to journalArticle

Glutaredoxins
AMP-Activated Protein Kinases
Medical problems
Metabolism
Type 2 Diabetes Mellitus
41 Citations (Scopus)

Hyperglycemic stress and carbon stress in diabetic glucotoxicity

Luo, X., Wu, J., Jing, S. & Yan, L. J., Feb 2016, In : Aging and Disease. 7, 1, p. 90-110 21 p.

Research output: Contribution to journalArticle

NAD
Carbon
Diabetes Complications
Proteome
Hyperglycemia
71 Citations (Scopus)

Role of RAGE in Alzheimer’s Disease

Cai, Z., Liu, N., Wang, C., Qin, B., Zhou, Y., Xiao, M., Chang, L., Yan, L. J. & Zhao, B., 1 May 2016, In : Cellular and Molecular Neurobiology. 36, 4, p. 483-495 13 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Cognition
Brain
Oxidative Stress
Advanced Glycosylation End Product-Specific Receptor
19 Citations (Scopus)

Sources and implications of NADH/NAD+ redox imbalance in diabetes and its complications

Wu, J., Jin, Z., Zheng, H. & Yan, L. J., 10 May 2016, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 9, p. 145-153 9 p.

Research output: Contribution to journalReview article

Diabetes Complications
NAD
Oxidation-Reduction
Sirtuins
Citric Acid Cycle
6 Citations (Scopus)
Gels
Proteins
Neurodegenerative diseases
Raphanus
Carbonylation