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  • Robert Luedtke
2019

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands

Chen, P. J., Taylor, M., Griffin, S. A., Amani, A., Hayatshahi, H., Korzekwa, K., Ye, M., Mach, R. H., Liu, J., Luedtke, R. R., Gordon, J. C. & Blass, B. E., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2690-2694 5 p.

Research output: Contribution to journalArticle

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)

Reilly, S. W., Riad, A. A., Hsieh, C. J., Sahlholm, K., Jacome, D. A., Griffin, S., Taylor, M., Weng, C. C., Xu, K., Kirschner, N., Luedtke, R. R., Parry, C., Malhotra, S., Karanicolas, J. & Mach, R. H., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5132-5147 16 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Analogues of Arylamide Phenylpiperazine Ligands to Investigate the Factors Influencing D3 Dopamine Receptor Bitropic Binding and Receptor Subtype Selectivity

Hayatshahi, H. S., Xu, K., Griffin, S. A., Taylor, M., Mach, R. H., Liu, J. & Luedtke, R. R., 19 Dec 2018, In : ACS Chemical Neuroscience. 9, 12, p. 2972-2983 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention

Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R., Forster, M. J., Sumien, N. & Ingram, D. K., 1 Jan 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors

Powell, G. L., Bonadonna, J. P., Vannan, A., Xu, K., Mach, R. H., Luedtke, R. R. & Neisewander, J. L., Dec 2018, In : Pharmacology Biochemistry and Behavior. 175, p. 123-129 7 p.

Research output: Contribution to journalArticle

Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors

Powell, G. L., Bonadonna, J. P., Vannan, A., Xu, K., Mach, R. H., Luedtke, R. R. & Neisewander, J. L., Aug 2018, In : Pharmacology Biochemistry and Behavior. 171, p. 46-53 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Dysregulated corticostriatal activity in open-field behavior and the head-twitch response induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine

Rangel-Barajas, C., Estrada-Sánchez, A. M., Barton, S. J., Luedtke, R. R. & Rebec, G. V., 1 Feb 2017, In : Neuropharmacology. 113, p. 502-510 9 p.

Research output: Contribution to journalArticle

Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores

Reilly, S. W., Griffin, S., Taylor, M., Sahlholm, K., Weng, C. C., Xu, K., Jacome, D. A., Luedtke, R. R. & Mach, R. H., 14 Dec 2017, In : Journal of Medicinal Chemistry. 60, 23, p. 9905-9910 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice

Malik, M., Rangel-Barajas, C., Mach, R. H. & Luedtke, R. R., 1 Sep 2016, In : Pharmacology Biochemistry and Behavior. 148, p. 136-144 9 p.

Research output: Contribution to journalArticle

1 Scopus citations