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  • Iok-Hou Pang
2020

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., Mar 2020, In : Progress in Retinal and Eye Research. 75, 100799.

Research output: Contribution to journalReview article

1 Scopus citations
2019
2 Scopus citations
2018

Assessment of aqueous humor dynamics in the rodent by constant flow infusion

Millar, J. C., Phan, T. N. & Pang, I. H., 1 Jan 2018, Methods in Molecular Biology. Humana Press Inc., p. 109-120 12 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

Lim, V., Schneider, E., Wu, H. & Pang, I. H., 26 Oct 2018, In : Nutrients. 10, 11

Research output: Contribution to journalReview article

2 Scopus citations

Effects of lentivirus-mediated C3 expression on trabecular meshwork cells and intraocular pressure

Tan, J., Fan, N., Wang, N., Feng, B., Yang, M., Liu, G., Wang, Y., Zhu, X., Kaufman, P. L., Pang, I. H. & Liu, X., Oct 2018, In : Investigative Ophthalmology and Visual Science. 59, 12, p. 4937-4944 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ligandomics: a paradigm shift in biological drug discovery

Li, W., Pang, I. H., Pacheco, M. T. F. & Tian, H., Mar 2018, In : Drug Discovery Today. 23, 3, p. 636-643 8 p.

Research output: Contribution to journalReview article

6 Scopus citations
2017

Involvement of Nrf2 in ocular diseases

Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I. H., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1703810.

Research output: Contribution to journalReview article

18 Scopus citations

Rapid repeatable in vivo detection of retinal reactive oxygen species

Fan, N., Silverman, S. M., Liu, Y., Wang, X., Kim, B. J., Tang, L., Clark, A. F., Liu, X. & Pang, I. H., Aug 2017, In : Experimental eye research. 161, p. 71-81 11 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2016

In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Kim, B. J., Silverman, S. M., Liu, Y., Wordinger, R. J., Pang, I. H. & Clark, A. F., 21 Apr 2016, In : Molecular Neurodegeneration. 11, 1, 93.

Research output: Contribution to journalArticle

16 Scopus citations

Novel therapeutic targets for reduction of intraocular pressure in primary open angle glaucoma

Mao, W., Liu, Y., Wordinger, R. J., Clark, A. F. & Pang, I. H., 11 Jun 2016, In : Chinese Journal of Ophthalmology. 52, 6, p. 471-475 5 p.

Research output: Contribution to journalReview article

The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A. F., Pang, I. H. & Wu, H., 1 Aug 2016, In : Redox Biology. 8, p. 98-109 12 p.

Research output: Contribution to journalArticle

27 Scopus citations
2015

A novel frameshift deletion in the COL1A1 gene identified in a Chinese family with osteogenesis imperfecta

Fan, N., Jonas, J. B., He, F., Yan, N. H., Wang, Y., Liu, L., Liu, D. L., Zhao, L., Pang, I. H. & Liu, X. Y., 30 Nov 2015, In : Genetics and Molecular Research. 14, 4, p. 15295-15300 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Caspase-7: A critical mediator of optic nerve injury-induced retinal ganglion cell death

Choudhury, S., Liu, Y., Clark, A. F. & Pang, I. H., 26 Aug 2015, In : Molecular Neurodegeneration. 10, 1, 40.

Research output: Contribution to journalArticle

19 Scopus citations
9 Scopus citations

Neuritin 1 promotes retinal ganglion cell survival and axonal regeneration following optic nerve crush

Sharma, T. P., Liu, Y., Wordinger, R. J., Pang, I. H. & Clark, A. F., 1 Jan 2015, In : Cell Death and Disease. 6, 2, e1661.

Research output: Contribution to journalArticle

15 Scopus citations

Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury

Nashine, S., Liu, Y., Kim, B. J., Clark, A. & Pang, I-H., 20 Nov 2015, In : Investigative Ophthalmology and Visual Science. 56, 1, p. 221-231 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Strain and age effects on aqueous humor dynamics in the mouse

Cameron Millar, J., Phan, T. N., Pang, I. H. & Clark, A. F., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 10, p. 5764-5776 13 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Erratum: Characterization of a transformed rat retinal ganglion cell line (Brain Research Molecular Brain Research (2001) 86 (1-12))

Krishnamoorthy, R. R., Agarwal, P., Prasanna, G., Vopat, K., Lambert, W., Sheedlo, H. J., Pang, I. H., Shade, D., Wordinger, R. J., Yorio, T., Clark, A. F. & Agarwal, N., 28 Jan 2014, In : Brain Research. 1544, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

In vivo optimization of 2,3-diaminopyrazine Rho Kinase inhibitors for the treatment of glaucoma

Chen, H. H., Namil, A., Severns, B., Ward, J., Kelly, C., Drace, C., McLaughlin, M. A., Yacoub, S., Li, B., Patil, R., Sharif, N., Hellberg, M. R., Rusinko, A., Pang, I. H. & Combrink, K. D., 15 Apr 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 8, p. 1875-1879 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Non-continuous measurement of intraocular pressure in laboratory animals

Millar, J. C. & Pang, I. H., 30 Oct 2014, In : Experimental eye research. 141, p. 74-90 17 p.

Research output: Contribution to journalArticle

5 Scopus citations

TGF-β2-mediated ocular hypertension is attenuated in SPARC-null mice

Swaminathan, S. S., Oh, D. J., Kang, M. H., Shepard, A. R., Pang, I-H. & Rhee, D. J., 1 Jul 2014, In : Investigative Ophthalmology and Visual Science. 55, 7, p. 4084-4097 14 p.

Research output: Contribution to journalArticle

20 Scopus citations
2013

Challenges in the development of glaucoma neuroprotection therapy

Liu, Y. & Pang, I-H., 1 Aug 2013, In : Cell and Tissue Research. 353, 2, p. 253-260 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Exon-level expression profiling of ocular tissues

Wagner, A. H., Anand, V. N., Wang, W. H., Chatterton, J. E., Sun, D., Shepard, A. R., Jacobson, N., Pang, I. H., DeLuca, A. P., Casavant, T. L., Scheetz, T. E., Mullins, R. F., Braun, T. A. & Clark, A. F., 1 Jun 2013, In : Experimental eye research. 111, p. 105-111 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Identification of PDE6D as a molecular target of anecortave acetate via a methotrexate-anchored yeast three-hybrid screen

Shepard, A. R., Conrow, R. E., Pang, I-H., Jacobson, N., Rezwan, M., Rutschmann, K., Auerbach, D., Sriramaratnam, R. & Cornish, V. W., 15 Mar 2013, In : ACS Chemical Biology. 8, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy

Dapper, J. D., Crish, S. D., Pang, I. H. & Calkins, D. J., 1 Nov 2013, In : Neurobiology of Disease. 59, p. 26-37 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

sCD44 overexpression increases intraocular pressure and aqueous outflow resistance

Giovingo, M., Nolan, M., McCarty, R., Pang, I. H., Clark, A. F., Beverley, R. M., Schwartz, S., Stamer, W. D., Walker, L., Grybauskas, A., Skuran, K., Kuprys, P. V., Yue, B. Y. J. T. & Knepper, P. A., 1 Nov 2013, In : Molecular vision. 19, p. 2151-2164 14 p.

Research output: Contribution to journalArticle

15 Scopus citations
2012

Existence of the canonical wnt signaling pathway in the human trabecular meshwork

Mao, W., Cameron Millar, J., Wang, W. H., Silverman, S. M., Liu, Y., Wordinger, R. J., Rubin, J. S., Pang, I. H. & Clark, A. F., 1 Oct 2012, In : Investigative Ophthalmology and Visual Science. 53, 11, p. 7043-7051 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death

Fernandes, K. A., Harder, J. M., Fornarola, L. B., Freeman, R. S., Clark, A. F., Pang, I. H., John, S. W. M. & Libby, R. T., 1 May 2012, In : Neurobiology of Disease. 46, 2, p. 393-401 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for Glaucoma

Yang, Q., Cho, K. S., Chen, H., Yu, D., Wang, W. H., Luo, G., Pang, I. H., Guo, W. & Chen, D. F., 1 Jun 2012, In : Investigative Ophthalmology and Visual Science. 53, 7, p. 3733-3741 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice

McDowell, C. M., Luan, T., Zhang, Z., Putliwala, T., Wordinger, R. J., Millar, J. C., John, S. W. M., Pang, I. H. & Clark, A. F., 1 Jul 2012, In : Experimental eye research. 100, p. 65-72 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2011
58 Scopus citations

Characterization of intraocular pressure responses of the Tibetan monkey (Macaca Thibetana)

Liu, G., Zeng, T., Yu, W., Yan, N., Wang, H., Cai, S. P., Pang, I. H. & Liu, X., 22 Jun 2011, In : Molecular vision. 17, p. 1405-1413 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Protective effect of a JNK inhibitor against retinal ganglion cell loss induced by acute moderate ocular hypertension

Sun, H., Wang, Y., Pang, I. H., Shen, J., Tang, X., Li, Y., Liu, C. & Li, B., 9 May 2011, In : Molecular vision. 17, p. 864-875 12 p.

Research output: Contribution to journalArticle

33 Scopus citations