Find Research Outputs

2019

Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework

Wu, R. R., Myers, R. A., Sperber, N., Voils, C. I., Neuner, J., McCarty, C. A., Haller, I. V., Harry, M., Fulda, K. G., Cross, D. S., Dimmock, D., Rakhra-Burris, T., Buchanan, A. H., Ginsburg, G. S. & Orlando, L. A., 1 Feb 2019, In : Genetics in Medicine. 21, 2, p. 331-338 8 p.

Research output: Contribution to journal › Article

Medical History Taking

Primary Health Care

Family Health

Clinical Decision Support Systems

Delivery of Health Care

Improvement in mental health following total hip arthroplasty: The role of pain and function

Nguyen, U. S. D. T., Perneger, T., Franklin, P. D., Barea, C., Hoffmeyer, P. & Lübbeke, A., 29 Jun 2019, In : BMC Musculoskeletal Disorders. 20, 1, 307.

Research output: Contribution to journal › Article

Open Access

Arthroplasty

Hip

Mental Health

Pain

Ontario

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., 1 Jan 2019, (Accepted/In press) In : Progress in Retinal and Eye Research. 100799.

Research output: Contribution to journal › Article

Glaucoma

Rodentia

Pressure

Intraocular Pressure

Low Tension Glaucoma

Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats

Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., 1 Jul 2019, In : Neurochemistry International. 127, p. 64-72 9 p.

Research output: Contribution to journal › Article

Autophagy

Stroke

Middle Cerebral Artery Infarction

Young Adult

Up-Regulation

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Yurvati, A., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., 1 May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journal › Article

Open Access

Ventriculoperitoneal Shunt

Cerebrospinal Fluid

Swine

Hydrocephalus

Cerebrospinal fluid

Intracranial atherosclerotic disease

Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., 1 Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.

Research output: Contribution to journal › Article

Intracranial Arteriosclerosis

Stroke

Therapeutics

Recurrence

Risk Management

1 Citation (Scopus)

In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection

Weiss, W., Pulse, M. E., Nguyen, P. & Growcott, E. J., 1 Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e02214-18.

Research output: Contribution to journal › Article

Klebsiella Infections

Monobactams

Carbapenems

Klebsiella pneumoniae

Uranyl Nitrate

In vivo imaging and biodistribution of near infrared dye loaded brain-metastatic-breast-cancer-cell-membrane coated polymeric nanoparticles

Kumar, P., Treuren, T. V., Ranjan, A. P., Chaudhary, P. & Vishwanatha, J. K., 15 Apr 2019, In : Nanotechnology. 30, 26, 265101.

Research output: Contribution to journal › Article

Cell membranes

Brain

Coloring Agents

Dyes

Nanoparticles

4 Citations (Scopus)

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journal › Article

Ischemic Preconditioning

Exercise

Clinical Trials

Hypoxia-Inducible Factor 1

Microglia

Knee Loading After ACL-R Is Related to Quadriceps Strength and Knee Extension Differences Across the Continuum of Care

Garrison, J. C., Hannon, J., Goto, S., Kosmopoulos, V., Aryal, S., Bush, C., Bothwell, J. M. & Singleton, S. B., 1 Jan 2019, In : Orthopaedic Journal of Sports Medicine. 7, 10

Research output: Contribution to journal › Article

Open Access

Continuity of Patient Care

Anterior Cruciate Ligament

Knee

Extremities

Anterior Cruciate Ligament Reconstruction

Large pelvic tubercle in orangutans relates to the adductor longus muscle

Shearer, B. M., Muchlinski, M. & Hammond, A. S., 1 Jan 2019, In : PeerJ. 2019, 8, e7273.

Research output: Contribution to journal › Article

Open Access

Pongo

Pongo pygmaeus

Muscle

Muscles

muscles

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D ₃ Receptor (D ₃ R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)

Reilly, S. W., Riad, A. A., Hsieh, C. J., Sahlholm, K., Jacome, D. A., Griffin, S., Taylor, M., Weng, C. C., Xu, K., Kirschner, N., Luedtke, R. T., Parry, C., Malhotra, S., Karanicolas, J. & Mach, R. H., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5132-5147 16 p.

Research output: Contribution to journal › Article

G-Protein-Coupled Receptors

Dopamine

Ligands

Adrenergic Agents

Pharmaceutical Preparations

1 Citation (Scopus)

Limited Intragenerational Mobility of Surgical Caseload of Iowa Hospitals

O'Neill, L., Dexter, F. & Epstein, R. H., 1 Jul 2019, In : Journal of Medical Systems. 43, 7, 187.

Research output: Contribution to journal › Article

Least-Squares Analysis

Economics

Statistics

Growth

Linkage, recombination, and mutation rate analyses of 19 X-chromosomal STR loci in Chinese Southern Han pedigrees

Yang, X., Chen, Y., Zeng, X., Chen, L., Liu, C., Liu, H., Xu, Q., Budowle, B. & Liu, C., 1 Nov 2019, In : International journal of legal medicine. 133, 6, p. 1691-1698 8 p.

Research output: Contribution to journal › Article

Linkage Disequilibrium

Mutation Rate

Pedigree

Genetic Recombination

Haplotypes

Locomotor activity and discriminative stimulus effects of five novel synthetic cathinone analogs in mice and rats

Gatch, M. B., Dolan, S. B. & Forster, M. J., 1 Jun 2019, In : Drug and Alcohol Dependence. 199, p. 50-58 9 p.

Research output: Contribution to journal › Article

Locomotion

N-Methyl-3,4-methylenedioxyamphetamine

Rats

Methamphetamine

Cocaine

1 Citation (Scopus)

Massively parallel sequence data of 31 autosomal STR loci from 496 Spanish individuals revealed concordance with CE-STR technology and enhanced discrimination power

The DNASEQEX Consortium, 1 Sep 2019, In : Forensic Science International: Genetics. 42, p. 49-55 7 p.

Research output: Contribution to journal › Article

Microsatellite Repeats

Technology

Alleles

Rubiaceae

Tandem Repeat Sequences

Metformin alters locomotor and cognitive function and brain metabolism in normoglycemic mice

Li, W., Chaudhari, K., Shetty, R., Winters, A., Gao, X., Hu, Z., Ge, W. P., Sumien, N., Forster, M., Liu, R. & Yang, S. H., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 949-963 15 p.

Research output: Contribution to journal › Article

Open Access

Metformin

Cognition

Brain

Energy Metabolism

Glycerolphosphate Dehydrogenase

Minority Physician Assistant Faculty: A Phenomenological Assessment of Factors Leading to Retention in the Faculty Role

LeLacheur, S. F., Bester, V., Oxendine, L. H., Guidry, C. B., Ryujin, D., Samuels, K. L., Maldonado, A., Bowen, D. & Himmerick, K., 1 Jun 2019, In : The journal of physician assistant education : the official journal of the Physician Assistant Education Association. 30, 2, p. 79-85 7 p.

Research output: Contribution to journal › Article

Physician Assistants

assistant

physician

minority

Mentors

Mitochondrial DNA control region variation in Lebanon, Jordan, and Bahrain

Zimmermann, B., Sturk-Andreaggi, K., Huber, N., Xavier, C., Saunier, J., Tahir, M., Chouery, E., Jalkh, N., Megarbane, A., Bodner, M., Coble, M., Irwin, J., Parsons, T. & Parson, W., Sep 2019, In : Forensic Science International: Genetics. 42, p. 99-102 4 p.

Research output: Contribution to journal › Article

Bahrain

Lebanon

Jordan

Mitochondrial DNA

Population

Models of poststroke depression and assessments of core depressive symptoms in rodents: How to choose?

Tao, X., Yang, W., Zhu, S., Que, R., Liu, C., Fan, T., Wang, J., Mo, D., Zhang, Z., Tan, J., Jin, K., Yenarih, M. A., Song, T. & Wang, Q., Dec 2019, In : Experimental Neurology. 322, 113060.

Research output: Contribution to journal › Review article

Rodentia

Stroke

Depression

Animal Models

Anhedonia

Multivariate group-level analysis for task fMRI data with canonical correlation analysis

Zhuang, X., Yang, Z., Sreenivasan, K. R., Mishra, V. R., Curran, T., Nandy, R. R. & Cordes, D., 1 Jul 2019, In : NeuroImage. 194, p. 25-41 17 p.

Research output: Contribution to journal › Article

Magnetic Resonance Imaging

Temporal Lobe

Episodic Memory

ROC Curve

Noise

Multivariate higher-order IRT model and MCMC algorithm for linking individual participant data from multiple studies

Mun, E. Y., Huo, Y., White, H. R., Suzuki, S. & de la Torre, J., 1 Jan 2019, In : Frontiers in Psychology. 10, JUN, 328.

Research output: Contribution to journal › Article

Open Access

Markov Chains

Feasibility Studies

Research

Meta-Analysis

Psychology

NADPH oxidase mediates membrane androgen receptor-induced neurodegeneration

Tenkorang, M. A. A., Duong, P. & Cunningham, R. L., 1 Jan 2019, In : Endocrinology. 160, 4, p. 947-963 17 p.

Research output: Contribution to journal › Article

Androgen Receptors

NAD

Oxidoreductases

Oxidative Stress

Phosphates

1 Citation (Scopus)

Nanopore sequencing: An enrichment-free alternative to mitochondrial DNA sequencing

Zascavage, R. R., Thorson, K. & Planz, J. V., 1 Jan 2019, In : Electrophoresis. 40, 2, p. 272-280 9 p.

Research output: Contribution to journal › Article

Nanopores

Mitochondrial DNA

DNA Sequence Analysis

Libraries

DNA

4 Citations (Scopus)

National Trends in Human Papillomavirus Awareness and Knowledge of Human Papillomavirus–Related Cancers

Wheldon, C. W., Krakow, M., Thompson, E. L. & Moser, R. P., 1 Apr 2019, In : American Journal of Preventive Medicine. 56, 4, p. e117-e123

Research output: Contribution to journal › Article

Neoplasms

Uterine Cervical Neoplasms

Penile Neoplasms

Anus Neoplasms

Vaccines

Non-fluorescent filters for fluorescence detection with in-line geometry

Kimball, J., Chavez, J., Ceresa, L., Shah, S., Gryczynski, I. & Gryczynski, Z., 16 May 2019, In : Methods and Applications in Fluorescence. 7, 3, 037001.

Research output: Contribution to journal › Article

Potassium Dichromate

lines (geometry)

chromates

Potassium

Fluorescence

Non-medical strategies to improve pregnancy outcomes of women with gestational diabetes mellitus a literature review

Al Hashmi, I., Nandy, K. & Seshan, V., Feb 2019, In : Sultan Qaboos University Medical Journal. 19, 1, p. e4-e10

Research output: Contribution to journal › Review article

Open Access

Gestational Diabetes

Pregnancy Outcome

Mothers

Blood Glucose Self-Monitoring

National Library of Medicine (U.S.)

1 Citation (Scopus)

Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

Das, P., Panda, S. K., Agarwal, B., Behera, S., Ali, S. M., Pulse, M. E., Solomkin, J. S., Opal, S. M., Bhandari, V. & Acharya, S., 1 Dec 2019, In : Scientific Reports. 9, 1, 2904.

Research output: Contribution to journal › Article

Open Access

Punctures

Ligation

Sepsis

Cytokines

Interleukin-10

Novel Investigation of the Deep Band of the Lateral Plantar Aponeurosis and Its Relationship With the Lateral Plantar Nerve

Beck, C. M., Dickerson, A. R., Kadado, K. J., Cohen, Z. A., Blair, S. E., Motley, T. A., Holcomb, J. C. & Fisher, C. L., 1 Nov 2019, In : Foot and Ankle International. 40, 11, p. 1325-1330 6 p.

Research output: Contribution to journal › Article

Foot

Metatarsal Bones

Diving

Aponeurosis

Obstetrics and Gynecology and Family Medicine Residents' Training and Knowledge on Emergency Contraception

Rapkin, R. B., Griner, S. B., Godcharles, C. L., Vamos, C. A., Neelamegam, M., Thompson, E. L. & Daley, E. M., 1 Jun 2019, In : Journal of Women's Health. 28, 6, p. 794-801 8 p.

Research output: Contribution to journal › Article

Postcoital Contraception

Gynecology

Obstetrics

Medicine

Internship and Residency

Origin and bioactivities of thiosulfinated FK228

Liu, X., Currens, G. C., Xue, L. & Cheng, Y., 1 Jan 2019, In : MedChemComm. 10, 4, p. 538-542 5 p.

Research output: Contribution to journal › Article

Bioactivity

Silica Gel

Burkholderia

Histone Deacetylases

romidepsin

Ovarian cancer: Current status and strategies for improving therapeutic outcomes

Chandra, A., Pius, C., Nabeel, M., Nair, M., Vishwanatha, J. K., Ahmad, S. & Basha, R., 1 Nov 2019, In : Cancer Medicine. 8, 16, p. 7018-7031 14 p.

Research output: Contribution to journal › Review article

Open Access

Ovarian Neoplasms

Platinum

Drug Therapy

Therapeutics

Survival Rate

Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment

Guenter, R., Aweda, T., Carmona Matos, D. M., Jang, S., Whitt, J., Cheng, Y. Q., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., 1 Jan 2019, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journal › Article

Neuroendocrine Tumors

Histone Deacetylase Inhibitors

Neuroendocrine Cells

Therapeutics

Tumor Cell Line

PaCIR: A tool to enhance pharmacist patient care intervention reporting

Clay, P. G., Burns, A. L., Isetts, B. J., Hirsch, J. D., Kliethermes, M. A. & Planas, L. G., 1 Sep 2019, In : Journal of the American Pharmacists Association. 59, 5, p. 615-623 9 p.

Research output: Contribution to journal › Article

Open Access

Pharmacists

Patient Care

Checklist

Teleconferencing

Language

Pancreatic cancer: An emphasis on current perspectives in immunotherapy

Patel, K., Siraj, S., Smith, C., Nair, M., Vishwanatha, J. K. & Basha, R., 1 Jan 2019, In : Critical Reviews in Oncogenesis. 24, 2, p. 105-118 14 p.

Research output: Contribution to journal › Article

Pancreatic Neoplasms

Immunotherapy

Neoplasms

Clinical Trials

Programmed Cell Death 1 Receptor

1 Citation (Scopus)

Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

McCarthy, C. G., Goulopoulou, S. & Webb, R. C., 1 Mar 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

Research output: Contribution to journal › Article

Blood Vessels

Hypertension

Inflammation

1 Citation (Scopus)

Personalized normative feedback for heavy drinking: An application of deviance regulation theory

Neighbors, C., DiBello, A. M., Young, C. M., Steers, M. L. N., Rinker, D. V., Rodriguez, L. M., Ryamond Knee, C., Blanton, H. & Lewis, M. A., 1 Apr 2019, In : Behaviour Research and Therapy. 115, p. 73-82 10 p.

Research output: Contribution to journal › Article

Drinking Behavior

Drinking

Health Behavior

Alcohol Drinking

Randomized Controlled Trials

8 Citations (Scopus)

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

International Society to Advance Alzheimer's Research and Treatment, Alzheimer's Association, Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 292-312 21 p.

Research output: Contribution to journal › Short survey

Dementia

Alzheimer Disease

Research

Population

Pharmacist-Led Chronic Care Management Services

Yuet, W. C., Gardea, J., Ebert, D. & Martin, R. D., 1 Sep 2019, In : Annals of family medicine. 17, 5, 1 p.

Research output: Contribution to journal › Article

Open Access

Pharmacists

1 Citation (Scopus)

Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection

Pulse, M. E., Weiss, W. J., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e01904-18.

Research output: Contribution to journal › Article

Bacteriocins

Clostridium difficile

Toxicology

Pharmacology

Mesocricetus

Pharmacy educator evaluation of web-based learning

Isaacs, A. N., Walton, A. M., Gonzalvo, J. D., Howard, M. L. & Nisly, S. A., 1 Dec 2019, In : Clinical Teacher. 16, 6, p. 630-635 6 p.

Research output: Contribution to journal › Article

Learning

Pharmacy Education

Students

Education

Pharmacy Schools

Photophysical properties and detection of Valrubicin on plasmonic platforms

Synak, A., Szczepańska, E., Grobelna, B., Gondek, J., Mońka, M., Gryczynski, I. & Bojarski, P., 1 Apr 2019, In : Dyes and Pigments. 163, p. 623-627 5 p.

Research output: Contribution to journal › Article

valrubicin

Silver

Nanoparticles

Plasmons

Gold

5 Citations (Scopus)

Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), 1 Jun 2019, In : Alzheimer's and Dementia. 15, 6, p. 764-775 12 p.

Research output: Contribution to journal › Article

Amyloid

Alzheimer Disease

Clinical Trials

Apolipoprotein E4

Validation Studies

Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

Rafii, M. S., Donohue, M. C., Matthews, D. C., Muranevici, G., Ness, S., O'Bryant, S. & Rissman, R. A., 1 Jan 2019, In : Journal of Alzheimer's Disease. 70, 1, p. 131-138 8 p.

Research output: Contribution to journal › Article

Intermediate Filaments

Down Syndrome

Alzheimer Disease

Biomarkers

Light

Plasmonically-powered hot carrier induced modulation of light emission in a two-dimensional GaAs semiconductor quantum well

Ashalley, E., Gryczynski, K., Wang, Z., Salamo, G. & Neogi, A., 7 Mar 2019, In : Nanoscale. 11, 9, p. 3827-3836 10 p.

Research output: Contribution to journal › Article

Open Access

Hot carriers

Light emission

Semiconductor quantum wells

Modulation

Metal nanoparticles

Population Pharmacokinetics of Pemetrexed in Adult Non–Small Cell Lung Cancer in Indian Patients

Srinivasan, M., Chaturvedula, A., Fossler, M. J., Patil, A., Gota, V. & Prabhash, K., 1 Jan 2019, In : Journal of Clinical Pharmacology. 59, 9, p. 1216-1224 9 p.

Research output: Contribution to journal › Article

Pemetrexed

Non-Small Cell Lung Carcinoma

Pharmacokinetics

Population

Markov Chains

Population pharmacokinetics of primaquine and the effect of hepatic and renal dysfunction: An exploratory approach

Sridharan, K., Sannala, C. K. R., Mallayasamy, S., Chaturvedula, A., Kadam, P., Hase, N., Shukla, A., Gogtay, N. & Thatte, U., 1 Jan 2019, In : Indian Journal of Pharmacology. 51, 1, p. 17-24 8 p.

Research output: Contribution to journal › Article

Primaquine

Pharmacokinetics

Kidney

Liver

Population

Potential two-step proteomic signature for Parkinson's disease: Pilot analysis in the Harvard Biomarkers Study

O'Bryant, S., Edwards, M., Zhang, F., Johnson, L. A., Hall, J., Kuras, Y. & Scherzer, C. R., 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 374-382 9 p.

Research output: Contribution to journal › Article

Open Access

Neurodegenerative Diseases

Proteomics

Parkinson Disease

Biomarkers

Alzheimer Disease

4 Citations (Scopus)

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

for Alzheimer’s Disease Neuroimaging Initiative, 1 Dec 2019, In : Scientific Reports. 9, 1, 1952.

Research output: Contribution to journal › Article

Open Access

Disease Progression

Alzheimer Disease

Learning

Neuroimaging

Area Under Curve

2 Citations (Scopus)

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

For the Alzheimer’s Disease Neuroimaging Initiative, 1 Dec 2019, In : Scientific Reports. 9, 1, 2235.

Research output: Contribution to journal › Article

Open Access

Disease Progression

Alzheimer Disease

Demography

Complement C1

Prodromal Symptoms