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The role of cholesterol metabolism and cholesterol transport in carcinogenesis: A review of scientific findings, relevant to future cancer therapeutics
Cruz, P. M. R., Mo, H., McConathy, W. J., Sabnis, N. & Lacko, A. G., 2013, In: Frontiers in Pharmacology. 4 SEP, Article 119.Research output: Contribution to journal › Review article › peer-review
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Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands
Chen, P. J., Taylor, M., Griffin, S. A., Amani, A., Hayatshahi, H., Korzekwa, K., Ye, M., Mach, R. H., Liu, J., Luedtke, R. R., Gordon, J. C. & Blass, B. E., 15 Sep 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2690-2694 5 p.Research output: Contribution to journal › Article › peer-review
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Decreased lecithin: Cholesterol acyltransferase activity in the plasma of hypercholesterolemic pigs
Lacko, A. G., Lee, S. M., Mirshahi, I., Hasler-Rapacz, J. & Kudchodkar, B. J., Apr 1992, In: Lipids. 27, 4, p. 266-269 4 p.Research output: Contribution to journal › Article › peer-review
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Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel
McConathy, W. J., Nair, M. P., Paranjape, S., Mooberry, L. & Lacko, A. G., Feb 2008, In: Anti-Cancer Drugs. 19, 2, p. 183-188 6 p.Research output: Contribution to journal › Article › peer-review
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Molecular Dynamics Reveal the Essential Role of Linker Motions in the Function of Cullin-RING E3 Ligases
Liu, J. & Nussinov, R., 2010, In: Journal of Molecular Biology. 396, 5, p. 1508-1523 16 p.Research output: Contribution to journal › Article › peer-review
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The ATP-depleting reagent "iodacetamide" induces the degradation of protein kinase C alpha (PKCα) in LLC-PK1 pig kidney cells
Dibas, A., Mia, A. J. & Yorio, T., 1 Dec 1997, In: FASEB Journal. 11, 3, p. A517Research output: Contribution to journal › Article › peer-review
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Recent progress in the discovery and development of negative allosteric modulators of mGluR5
Lindsley, C. W. & Emmitte, K. A., Jul 2009, In: Current Opinion in Drug Discovery and Development. 12, 4, p. 446-457 12 p.Research output: Contribution to journal › Review article › peer-review
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Targeting BRCA1-and BRCA2-deficient cells with RAD52 small molecule inhibitors
Huang, F., Goyal, N., Sullivan, K., Hanamshet, K., Patel, M., Mazina, O. M., Wang, C. X., An, W. F., Spoonamore, J., Metkar, S., Emmitte, K. A., Cocklin, S., Skorski, T. & Mazin, A. V., 19 May 2016, In: Nucleic Acids Research. 44, 9, p. 4189-4199 11 p.Research output: Contribution to journal › Article › peer-review
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Enzyme purification by affinity chromatography using a non-covalently bound adsorbent
Lacko, A. G. & F. Chen, T., 11 Jan 1977, In: Journal of Chromatography A. 130, C, p. 446-450 5 p.Research output: Contribution to journal › Article › peer-review
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Role of sodium on H+ excretion in the integument of the leopard frog Rana pipiens
Page, R., Frazier, L. W. & Yorio, T., 1988, In: Comparative Biochemistry and Physiology -- Part A: Physiology. 91, 1, p. 53-59 7 p.Research output: Contribution to journal › Article › peer-review
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Effect of furosemide on unidirectional fluxes of sodium and chloride across the skin of the frog, Rana pipiens
Yorio, T. & Bentley, P. J., 14 Dec 1976, In: BBA - Biomembranes. 455, 3, p. 831-836 6 p.Research output: Contribution to journal › Article › peer-review
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Targets of neuroprotection in glaucoma
He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. R. & Yorio, T., 1 Jan 2018, In: Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.Research output: Contribution to journal › Article › peer-review
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A convergent coupling strategy for the formation of polycyclic ethers: Stereoselective synthesis of the BCDE fragment of brevetoxin A
Crimmins, M. T., McDougall, P. J. & Emmitte, K. A., 1 Sep 2005, In: Organic Letters. 7, 18, p. 4033-4036 4 p.Research output: Contribution to journal › Article › peer-review
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Tribute to Ruth Nussinov
Keskin, O., Miller, Y., Liu, J. & Lu, S., 1 Jul 2021, In: Journal of Physical Chemistry B. 125, 25, p. 6733-6734 2 p.Research output: Contribution to journal › Article › peer-review
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FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C δ signaling
Hung, J. H., Lu, Y. S., Wang, Y. C., Ma, Y. H., Wang, D. S., Kulp, S. K., Muthusamy, N., Byrd, J. C., Cheng, A. L. & Chen, C. S., 15 Feb 2008, In: Cancer Research. 68, 4, p. 1204-1212 9 p.Research output: Contribution to journal › Article › peer-review
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Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects
Zuo, Z., Babu, K., Ganguly, C., Zolekar, A., Newsom, S., Rajan, R., Wang, Y. C. & Liu, J., Apr 2022, In: CRISPR Journal. 5, 2, p. 329-340 12 p.Research output: Contribution to journal › Article › peer-review
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Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2
Felts, A. S., Rodriguez, A. L., Smith, K. A., Engers, J. L., Morrison, R. D., Byers, F. W., Blobaum, A. L., Locuson, C. W., Chang, S., Venable, D. F., Niswender, C. M., Daniels, J. S., Conn, P. J., Lindsley, C. W. & Emmitte, K. A., 25 Nov 2015, In: Journal of Medicinal Chemistry. 58, 22, p. 9027-9040 14 p.Research output: Contribution to journal › Article › peer-review
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Lipoprotein substrate binding site of LCAT karen murray
Nair, M. P., Haydn Pritchard, P. & Lacko, A. G., 1 Dec 1998, In: FASEB Journal. 12, 8, p. A1379Research output: Contribution to journal › Article › peer-review
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Dependence of insulin secretion from permeabilized pancreatic β-cells on the activation of Ca2+/calmodulin-dependent protein kinase II: A re-evaluation of inhibitor studies
Bhatt, H. S., Conner, B. P., Prasanna, G., Yorio, T. & Easom, R. A., 1 Dec 2000, In: Biochemical Pharmacology. 60, 11, p. 1655-1663 9 p.Research output: Contribution to journal › Article › peer-review
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The reaction of triplet nitrenes with oxygen: A computational study
Liu, J., Hadad, C. M. & Platz, M. S., 17 Feb 2005, In: Organic Letters. 7, 4, p. 549-552 4 p.Research output: Contribution to journal › Article › peer-review
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Asymmetric total synthesis of (-)-isolaurallene [18]
Crimmins, M. T. & Emmitte, K. A., 21 Feb 2001, In: Journal of the American Chemical Society. 123, 7, p. 1533-1534 2 p.Research output: Contribution to journal › Letter › peer-review
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Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells
Wang, Y. C., Stein, J. W., Lynch, C. L., Tran, H. T., Lee, C. Y., Coleman, R., Hatch, A., Antontsev, V. G., Chy, H. S., O'Brien, C. M., Murthy, S. K., Laslett, A. L., Peterson, S. E. & Loring, J. F., 25 Aug 2015, In: Scientific Reports. 5, 13317.Research output: Contribution to journal › Article › peer-review
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Endothelin-1 induces nitric oxide synthase-2 expression in human non-pigmented ciliary epithelial cells
Prasanna, G., Krishnamoorthy, R., Hulet, C., Zhang, H., Zhang, X. & Yorio, T., 2000, In: Experimental eye research. 71, 5, p. 535-539 5 p.Research output: Contribution to journal › Editorial
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Evaluation of lipid and lipoprotein metabolism in rats as a model for studying age-related physiological changes
Lacko, A. G., Carlile, S. & Kudchodkar, B. J., 1984, In: Journals of Gerontology. 39, 5, p. 513-520 8 p.Research output: Contribution to journal › Article › peer-review
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Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors
Lindsley, C. W., Emmitte, K. A., Hopkins, C. R., Bridges, T. M., Gregory, K. J., Niswender, C. M. & Conn, P. J., 8 Jun 2016, In: Chemical Reviews. 116, 11, p. 6707-6741 35 p.Research output: Contribution to journal › Review article › peer-review