Find Research Outputs

2019

Artificial Intelligence and Pharmacometrics: Time to Embrace, Capitalize, and Advance?

Chaturvedula, A., Calad-Thomson, S., Liu, C., Sale, M., Gattu, N. & Goyal, N., Jul 2019, In : CPT: Pharmacometrics and Systems Pharmacology. 8, 7, p. 440-443 4 p.

Research output: Contribution to journalComment/debate

Open Access
Artificial Intelligence
Artificial intelligence

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

Winston, C. N., Romero, H. K., Ellisman, M., Nauss, S., Julovich, D. A., Conger, T., Hall, J. R., Campana, W., O’Bryant, S. E., Nievergelt, C. M., Baker, D. G., Risbrough, V. B. & Rissman, R. A., 2 Oct 2019, In : Frontiers in Neuroscience. 13, 1005.

Research output: Contribution to journalArticle

Open Access
Brain Concussion
Exosomes
Astrocytes
Proteins
Neurogranin
1 Citation (Scopus)

Assessing the Performance of the Nonbonded Mg2+ Models in a Two-Metal-Dependent Ribonuclease

Zuo, Z. & Liu, J., 28 Jan 2019, In : Journal of Chemical Information and Modeling. 59, 1, p. 399-408 10 p.

Research output: Contribution to journalArticle

Ribonucleases
Metals
performance
Lennard-Jones potential
Molecular dynamics
3 Citations (Scopus)

Assessment of impact of DNA extraction methods on analysis of human remain samples on massively parallel sequencing success

Zeng, X., Elwick, K., Mayes, C., Takahashi, M., King, J. L., Gangitano, D., Budowle, B. & Hughes-Stamm, S., 14 Jan 2019, In : International journal of legal medicine. 133, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
DNA
Bone and Bones
Hair
Single Nucleotide Polymorphism

Association of Entrepreneurial Traits With Interest in Becoming a Pharmacist Provider Among Student Pharmacists

Nili, M., Shaikh, N. F., Dwibedi, N. & Madhavan, S. S., 1 Jan 2019, (Accepted/In press) In : Journal of Pharmacy Practice.

Research output: Contribution to journalArticle

Pharmacists
Students
Motivation
Linear Models
Analysis of Variance
Students
Pharmacy Education
Random Allocation
Education
Feedback
1 Citation (Scopus)

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12

Pan, Z., Ai, T., Chang, P. C., Liu, Y., Liu, J., Maruyama, M., Homsi, M., Fishbein, M. C., Rubart, M., Lin, S. F., Xiao, D., Chen, H., Chen, P. S., Shou, W. & Li, B. Y., Feb 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 2, p. H371-H379

Research output: Contribution to journalArticle

Tacrolimus Binding Protein 1A
Electrophysiology
Atrial Fibrillation
Transgenic Mice
Tacrolimus Binding Proteins
1 Citation (Scopus)
Metadata
Meta-Analysis
Alcohols
Therapeutics
Random Allocation

Author Correction: Magnesium intake and mortality due to liver diseases: Results from the Third National Health and Nutrition Examination Survey Cohort (Scientific Reports, (2017), 7, 1, (17913), 10.1038/s41598-017-18076-5)

Wu, L., Zhu, X., Fan, L., Kabagambe, E. K., Song, Y., Tao, M., Zhong, X., Hou, L., Shrubsole, M. J., Liu, J. & Dai, Q., 1 Dec 2019, In : Scientific Reports. 9, 1, 6983.

Research output: Contribution to journalComment/debate

Open Access
Nutrition Surveys
Magnesium
Liver Diseases
Mortality

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Sep 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access
Meta-Analysis
Immunity
Alzheimer Disease
Lipids

Bacterial microbiomes of Ixodes scapularis ticks collected from Massachusetts and Texas, USA

Thapa, S., Zhang, Y. & Allen, M. S., 24 Jun 2019, In : BMC Microbiology. 19, 1, 138.

Research output: Contribution to journalArticle

Open Access
Ixodes
Microbiota
Ticks
Rickettsia
Geography
1 Citation (Scopus)

Basics on the use of acid-sensing ion channels' inhibitors as therapeutics

Dibas, J., Al-Saad, H. & Dibas, A., Mar 2019, In : Neural Regeneration Research. 14, 3, p. 395-398 4 p.

Research output: Contribution to journalReview article

Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels
Drug Repositioning
Neuroprotective Agents
Blood-Retinal Barrier
1 Citation (Scopus)
Open Access
Medical problems
diabetes
Hospitalization
Health
sampling

Bioinspired Nanoparticles Engineered for Enhanced Delivery to the Bone

Gdowski, A. S., Lampe, J. B., Lin, V. J. T., Joshi, R., Wang, Y. C., Mukerjee, A., Vishwanatha, J. K. & Ranjan, A. P., 25 Oct 2019, In : ACS Applied Nano Materials. 2, 10, p. 6249-6257 9 p.

Research output: Contribution to journalArticle

Bone
Nanoparticles
Cells
Integrins
Cell membranes

Biomechanical Efficacy of Shear-Reducing Diabetic Insoles: Elaborations on Future Design Criteria

Yavuz, M., Ersen, A., Richardson, M., Adams, L. S., Holmes, C. F., Wijesundara, M. B. J., Wukich, D. K. & La Fontaine, J., 1 Apr 2019, In : Journal of Prosthetics and Orthotics. 31, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

Gait
Shoes
Orthotics
Analysis of variance (ANOVA)
Orthotic Devices
2 Citations (Scopus)

Blood-based biomarkers for Down syndrome and Alzheimer's disease: A systematic review

Petersen, M. E. & O'Bryant, S., 1 Jul 2019, In : Developmental Neurobiology. 79, 7, p. 699-710 12 p.

Research output: Contribution to journalReview article

Down Syndrome
Alzheimer Disease
Biomarkers
Chromosomes, Human, Pair 21
Prodromal Symptoms
2 Citations (Scopus)

Blood Biomarkers for Use in Alzheimer Disease - Moving from "if" to "how?"

O'Bryant, S. E., Sep 2019, In : JAMA Neurology. 76, 9, p. 1009-1010 2 p.

Research output: Contribution to journalEditorial

Alzheimer Disease
Biomarkers

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Oct 2019, In : Alzheimer's and Dementia. 15, 10, p. 1274-1285 12 p.

Research output: Contribution to journalArticle

Open Access
Sex Characteristics
Brain
Alzheimer Disease
Biomarkers
Apolipoprotein E4
1 Citation (Scopus)

Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach

Prokai-Tatrai, K., De La Cruz, D. L., Nguyen, V., Ross, B. P., Toth, I. & Prokai, L., Jul 2019, In : Pharmaceutics. 11, 7, 349.

Research output: Contribution to journalArticle

Open Access
Thyrotropin-Releasing Hormone
Prodrugs
prolyl oligopeptidase
Brain
Peptides
1 Citation (Scopus)

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5

Mangoni, A. A., Eynde, J. J. V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M. E., Gomes, P. A. C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J. M., Luque, F. J., Rautio, J., Karaman, R., Vasconcelos, M. H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., Gütschow, M. & 6 others, Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L. A., Ragno, R. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 13, 2415.

Research output: Contribution to journalReview article

Open Access
Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 others, Gütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 1, p. 1-12 12 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations
1 Citation (Scopus)

Cancer survivors' experiences with breakdowns in patient-centered communication

Street, R. L., Spears, E. C., Madrid, S. & Mazor, K. M., 1 Feb 2019, In : Psycho-Oncology. 28, 2, p. 423-429 7 p.

Research output: Contribution to journalArticle

Survivors
Communication
Neoplasms
Delivery of Health Care
Foster Home Care
5 Citations (Scopus)

Cannabinoid-like effects of five novel carboxamide synthetic cannabinoids

Gatch, M. B. & Forster, M. J., Jan 2019, In : NeuroToxicology. 70, p. 72-79 8 p.

Research output: Contribution to journalArticle

Dronabinol
Cannabinoids
Locomotion
Drug Legislation
Cannabis

Cardiac structure and function in well-healed burn survivors

Samuel, T. J., Nelson, M. D., Nasirian, A., Jaffery, M., Moralez, G., Romero, S. A., Cramer, M. N., Huang, M., Kouda, K., Hieda, M., Sarma, S. & Crandall, C. G., 20 Feb 2019, In : Journal of Burn Care and Research. 40, 2, p. 235-241 7 p.

Research output: Contribution to journalArticle

Open Access
Survivors
Ventricular Remodeling
Exercise
Left Ventricular Function
Wounds and Injuries
1 Citation (Scopus)
Motor Skills Disorders
Pressure
Autism Spectrum Disorder
Motor Skills
Child Development

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

Research output: Contribution to journalArticle

Astrocytes
Oxidative Stress
Neuroprotective Agents
Energy Metabolism
Glutamic Acid

Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress

Yang, X., Song, J. & Yan, L. J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.

Research output: Contribution to journalArticle

Open Access
Dihydrolipoamide Dehydrogenase
Oxidative stress
Oxidative Stress
Medical problems
Type 2 Diabetes Mellitus
1 Citation (Scopus)

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R., Sun, J., Pathak, G., Johnson, L., O’Bryant, S. & Phillips, N., Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticle

Open Access
Mexican Americans
Medical problems
Mitochondrial DNA
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
1 Citation (Scopus)

Climatic adaptation in human inferior nasal turbinate morphology: Evidence from Arctic and equatorial populations

Marks, T. N., Maddux, S. D., Butaric, L. N. & Franciscus, R. G., Jul 2019, In : American Journal of Physical Anthropology. 169, 3, p. 498-512 15 p.

Research output: Contribution to journalArticle

Turbinates
Arctic
Nose
Population
evidence
1 Citation (Scopus)

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival

Cognitive training and transcranial direct current stimulation in mild cognitive impairment: A randomized pilot trial

Das, N., Spence, J. S., Aslan, S., Vanneste, S., Mudar, R., Rackley, A., Quiceno, M. & Chapman, S. B., 1 Jan 2019, In : Frontiers in Neuroscience. 13, APR, 307.

Research output: Contribution to journalArticle

Open Access
Cerebrovascular Circulation
Executive Function
Episodic Memory
Cognitive Dysfunction
Transcranial Direct Current Stimulation
1 Citation (Scopus)

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Vincristine
tolfenamic acid
Cell Cycle
Apoptosis

Commentaries on health services research

Smith, B. J., Hooker, R. S., McMichael, B. J., Salsberg, E. & Forister, J. G., 1 Jan 2019, In : JAAPA : official journal of the American Academy of Physician Assistants. 32, 1, p. 54-56 3 p.

Research output: Contribution to journalArticle

Health Services Research
2 Citations (Scopus)

Comparison of diabetic nephropathy between male and female eNOS-/- db/db mice

Ma, Y., Li, W., Shotorbani, P. Y., Dubansky, B. H., Huang, L., Chaudhari, S., Wu, P., Wang, L. A., Ryou, M. G., Zhou, Z. & Ma, R., May 2019, In : American Journal of Physiology - Renal Physiology. 316, 5, p. F889-F897

Research output: Contribution to journalArticle

Diabetic Nephropathies
Sex Characteristics
Kidney
Physiological Phenomena
Albuminuria
Open Access
Mexican Americans
National Health and Nutrition Examination Survey
Nutrition Surveys
Micronutrients
dietary minerals
3 Citations (Scopus)

Compound stutter in D2S1338 and D12S391

Woerner, A. E., King, J. L. & Budowle, B., Mar 2019, In : Forensic Science International: Genetics. 39, p. 50-56 7 p.

Research output: Contribution to journalArticle

Linear Models
Nucleotides
High-Throughput Nucleotide Sequencing
3 Citations (Scopus)

Considerations in addressing the opioid epidemic and chronic pain within the USA

Marshall, B., Bland, M. K., Hulla, R. & Gatchel, R. J., 1 Mar 2019, In : Pain management. 9, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

Chronic Pain
Opioid Analgesics
Neurobiology
Pain Management
Therapeutics
2 Citations (Scopus)

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Copper
Neoplasms
Powders
tolfenamic acid
Cell Line
Open Access
Retinal Ganglion Cells
Glaucoma
Publications
Cell Death
Animal Models
Open Access
National Institute of Neurological Disorders and Stroke
Organized Financing
Astrocytes
Histones
Methylation
Opioid Analgesics
Prescriptions
Logistic Models
North American Indians
Cannabis
3 Citations (Scopus)

Dental opinion leaders’ perspectives on barriers and facilitators to HPV-related prevention

Griner, S. B., Thompson, E. L., Vamos, C. A., Chaturvedi, A. K., Vazquez-Otero, C., Merrell, L. K., Kline, N. S. & Daley, E. M., 3 Aug 2019, In : Human Vaccines and Immunotherapeutics. 15, 7-8, p. 1856-1862 7 p.

Research output: Contribution to journalArticle

Tooth
Oropharyngeal Neoplasms
Dental Research
Education
Papillomavirus Vaccines

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands

Chen, P. J., Taylor, M., Griffin, S. A., Amani, A., Hayatshahi, H., Korzekwa, K., Ye, M., Mach, R. H., Liu, J., Luedtke, R. R., Gordon, J. C. & Blass, B. E., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2690-2694 5 p.

Research output: Contribution to journalArticle

Benzamides
Dopamine D3 Receptors
Pharmacokinetics
Dopamine Receptors
Substance-Related Disorders
2 Citations (Scopus)

Development and Validation of an Algorithm to Classify as Equivalent the Procedures in ICD-10-PCS That Differ only by Laterality

Epstein, R. H., Dexter, F. & O'Neill, L., 1 Jun 2019, In : Anesthesia and analgesia. 128, 6, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

International Classification of Diseases
Inpatients
Language
Operative Surgical Procedures
Confidence Intervals
1 Citation (Scopus)

Development of a motivational interviewing genetic counseling intervention to increase cascade cholesterol screening in families of children with familial hypercholesterolemia

Kruger, V., Redlinger-Grosse, K., Walters, S. T., Ash, E., Cragun, D., McCarthy Veach, P. & Zierhut, H. A., 1 Oct 2019, In : Journal of Genetic Counseling. 28, 5, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

Motivational Interviewing
Hyperlipoproteinemia Type II
Genetic Engineering
Health Behavior
Genetic Counseling

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), Jul 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Alzheimer Disease
Brain
Frontal Lobe
1 Citation (Scopus)

Differential effects of protein kinase C-eta on apoptosis versus senescence

Basu, A., Pal, D. & Blaydes, R., 1 Mar 2019, In : Cellular Signalling. 55, p. 1-7 7 p.

Research output: Contribution to journalArticle

Apoptosis
Doxorubicin
Breast Neoplasms
protein kinase C eta
Galactosidases

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

d’Oliveira, G. D. C., Custodio, J. M. F., Moura, A. F., Napolitano, H. B., Pérez, C. N., Moraes, M. O., Prókai, L. & Perjési, P., 1 Sep 2019, In : Medicinal Chemistry Research. 28, 9, p. 1448-1460 13 p.

Research output: Contribution to journalArticle

Open Access
Chalcones
Chalcone
Quinolones
Glutathione
Toxicity

Direct Oral Anticoagulants in Chronic Liver Disease

Steuber, T. D., Howard, M. & Nisly, S. A., 1 Oct 2019, In : Annals of Pharmacotherapy. 53, 10, p. 1042-1049 8 p.

Research output: Contribution to journalReview article

Anticoagulants
Liver Diseases
Chronic Disease
Clinical Trials
Information Storage and Retrieval

Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

Felts, A. S., Bollinger, K. A., Brassard, C. J., Rodriguez, A. L., Morrison, R. D., Scott Daniels, J., Blobaum, A. L., Niswender, C. M., Jones, C. K., Jeffrey Conn, P., Emmitte, K. A. & Lindsley, C. W., 1 Jan 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 47-50 4 p.

Research output: Contribution to journalArticle

Aldehyde Oxidase
Metabotropic Glutamate 5 Receptor
Metabotropic Glutamate Receptors
Metabolism
Modulators