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(3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: Discovery of a new tool compound with activity in the OSS mouse model of addiction

Lindsley, C. W., Bates, B. S., Menon, U. N., Jadhav, S. B., Kane, A. S., Jones, C. K., Rodriguez, A. L., Conn, P. J., Olsen, C. M., Winder, D. G. & Emmitte, K. A., 17 Aug 2011, In : ACS Chemical Neuroscience. 2, 8, p. 471-482 12 p.

Research output: Contribution to journal › Article

18 Scopus citations

(Xeno)estrogen sensitivity of smooth muscle BK channels conferred by the regulatory β1 subunit: A study of β1 knockout mice

Dick, G. M. & Sanders, K. M., 30 Nov 2001, In : Journal of Biological Chemistry. 276, 48, p. 44835-44840 6 p.

Research output: Contribution to journal › Article

Open Access
78 Scopus citations

[13] Synthesis and applications of affinity matrix containing immobilized βγ subunits of G proteins

Pang, I. H., Smrcka, A. V. & Sternweis, P. C., 19 Aug 1994, In : Methods in Enzymology. 237, p. 154-174 21 p.

Research output: Contribution to journal › Article

[3H]4-(dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)- butyl)benzamide: A selective radioligand for dopamine D3 receptors. II. Quantitative analysis of dopamine D3 and D2 receptor density ratio in the caudate-putamen

Xu, J., Hassanzadeh, B., Chu, W., Tu, Z., Jones, L. A., Luedtke, R. R., Perlmutter, J. S., Mintun, M. A. & Mach, R. H., 1 Jun 2010, In : Synapse. 64, 6, p. 449-459 11 p.

Research output: Contribution to journal › Article

30 Scopus citations

[3H]4-(dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin-1-yl) butyl]benzamide, a selective radioligand for dopamine D3 receptors. I. In vitro characterization

Xu, J., Chu, W., Tu, Z., Jones, L. A., Luedtke, R. R., Perlmutter, J. S., Mintun, M. A. & Mach, R. H., 1 Sep 2009, In : Synapse. 63, 9, p. 717-728 12 p.

Research output: Contribution to journal › Article

24 Scopus citations

[ 99 mTc-HYNIC-N-dodecylamide]:a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging

Isaac-Olivé, K., Ocampo-García, B. E., Aranda-Lara, L., Santos-Cuevas, C. L., Jiménez-Mancilla, N. P., Luna-Gutiérrez, M. A., Medina, L. A., Nagarajan, B., Sabnis, N., Raut, S., Prokai, L. & Lacko, A. G., 14 Jan 2019, In : Nanoscale. 11, 2, p. 541-551 11 p.

Research output: Contribution to journal › Article

2 Scopus citations

[Aladan3]TIPP: A fluorescent δ-opioid antagonist with high δ-receptor binding affinity and δ selectivity

Chen, H., Chung, N. N., Lemieux, C., Zelent, B., Vanderkooi, J. M., Gryczynski, I., Wilkes, B. C. & Schiller, P. W., 20 Jun 2005, In : Biopolymers - Peptide Science Section. 80, 2-3, p. 325-331 7 p.

Research output: Contribution to journal › Article

23 Scopus citations

[Capacitative Ca2+ entry is involved in ACh-induced distal colon smooth muscle contraction in rats].

Kong, D. H., Zhou, H., Song, J., Ke, D. P., Hu, J. L., Li, Z. W. & Ma, R., 1 Jan 2006, In : Sheng li xue bao : [Acta physiologica Sinica]. 58, 2, p. 149-156 8 p.

Research output: Contribution to journal › Article

3 Scopus citations

[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium].

Liu, L., Zhang, H. H., Ding, G. X., Cheng, Y. L., Yan, L. J. & Benjamin, I. J., Feb 2004, In : Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 20, 1, p. 30-33 4 p.

Research output: Contribution to journal › Article

[Glu2]TRH dose-dependently attenuates TRH-evoked analeptic effect in mice

Nguyen, V., Zharikova, A. D., Prokai-Tatrai, K. & Prokai, L., 1 Apr 2010, In : Brain Research Bulletin. 82, 1-2, p. 83-86 4 p.

Research output: Contribution to journal › Article

2 Scopus citations

[Role of restricted nitric oxide overproduction in the cardioprotective effect of adaptation to intermittent hypoxia].

goriacheva, A. V., Belkina, L. M., Terekhina, O. L., Dawney, H. F., Mallet, R. T., Smirin, B. V., Smirnova, E. A., Mashina, S. I. & Manukhina, E. B., 1 Jan 2012, In : Patologicheskaia fiziologiia i èksperimental'naia terapiia. 1, p. 23-28 6 p.

Research output: Contribution to journal › Article

1 Scopus citations

[Store-operated Ca2+ channels in rat colonic smooth muscle cells].

Zhou, H., Kong, D. H., Ma, R., Ke, D. P., Hu, J. L. & Song, J., 1 Jan 2006, In : Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 22, 2, p. 220-224 5 p.

Research output: Contribution to journal › Article

1 Scopus citations

#drunktwitter: Examining the relations between alcohol-related Twitter content and alcohol willingness and use among underage young adults

Litt, D. M., Lewis, M. A., Spiro, E. S., Aulck, L., Waldron, K. A., Head-Corliss, M. K. & Swanson, A., 1 Dec 2018, In : Drug and Alcohol Dependence. 193, p. 75-82 8 p.

Research output: Contribution to journal › Article

3 Scopus citations

10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat

Hickey, R. W., Zhu, R. L., Alexander, H. L., Jin, K. L., Stetler, R. A., Chen, J., Kochanek, P. M. & Graham, S. H., 23 Jun 2000, In : Molecular Brain Research. 79, 1-2, p. 169-173 5 p.

Research output: Contribution to journal › Article

13 Scopus citations

10β,17α-Dihydroxyestra-1,4-dien-3-one: A Bioprecursor Prodrug Preferentially Producing 17α-Estradiol in the Brain for Targeted Neurotherapy

Prokai-Tatrai, K., Nguyen, V. & Prokai, L., 21 Nov 2018, In : ACS Chemical Neuroscience. 9, 11, p. 2528-2533 6 p.

Research output: Contribution to journal › Article

2 Scopus citations

11th annual retrovirus conference. Drug update: the old, the new, the still to come.

Clay, P. G., 1 Jan 2004, In : Positively aware : the monthly journal of the Test Positive Aware Network. 15, 2

Research output: Contribution to journal › Article

13C labeling indicates that the epoxide-containing amino acid of HC- toxin is biosynthesized by head-to-tail condensation of acetate

Cheng, Y., Le, L. D., Walton, J. D. & Bishop, K. D., 1 Jan 1999, In : Journal of Natural Products. 62, 1, p. 143-145 3 p.

Research output: Contribution to journal › Article

5 Scopus citations

17β-Estradiol attenuates blood-brain barrier disruption induced by cerebral ischemia-reperfusion injury in female rats

Liu, R., Wen, Y., Perez, E., Wang, X., Day, A. L., Simpkins, J. W. & Yang, S. H., 26 Oct 2005, In : Brain Research. 1060, 1-2, p. 55-61 7 p.

Research output: Contribution to journal › Article

86 Scopus citations

17 β-estradiol attenuates poststroke depression and increases neurogenesis in female ovariectomized rats

Cheng, Y., Su, Q., Shao, B., Cheng, J., Wang, H., Wang, L., Lin, Z., Ruan, L., ZhuGe, Q. & Jin, K., 9 Dec 2013, In : BioMed Research International. 2013, 392434.

Research output: Contribution to journal › Article

15 Scopus citations

17-β estradiol can reduce secondary ischemic damage and mortality of subarachnoid hemorrhage

Yang, S. H., He, Z., Wu, S. S., He, Y. J., Cutright, J., Millard, W. J., Day, A. L. & Simpkins, J. W., 1 Jan 2001, In : Journal of Cerebral Blood Flow and Metabolism. 21, 2, p. 174-181 8 p.

Research output: Contribution to journal › Article

65 Scopus citations

17β-estradiol delivered in eye drops: Evidence of impact on protein networks and associated biological processes in the rat retina through quantitative proteomics

Prokai, L., Zaman, K., Nguyen, V. & Prokai-Tatrai, K., Feb 2020, In : Pharmaceutics. 12, 2, 101.

Research output: Contribution to journal › Article

Open Access
1 Scopus citations

17β-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats

Fan, T., Yang, S. H., Johnson, E., Osteen, B., Hayes, R., Day, A. L. & Simpkins, J. W., 12 Dec 2003, In : Brain Research. 993, 1-2, p. 10-17 8 p.

Research output: Contribution to journal › Article

29 Scopus citations

17β-estradiol eye drops protect the retinal ganglion cell layer and preserve visual function in an in vivo model of glaucoma

Prokai-Tatrai, K., Xin, H., Nguyen, V., Szarka, S., Blazics, B., Prokai, L. & Koulen, P., 5 Aug 2013, In : Molecular Pharmaceutics. 10, 8, p. 3253-3261 9 p.

Research output: Contribution to journal › Article

39 Scopus citations

17β-estradiol protects against the progression of hypertension during adulthood in a mouse model of systemic lupus erythematosus

Gilbert, E. L., Mathis, K. W. & Ryan, M. J., 1 Mar 2014, In : Hypertension. 63, 3, p. 616-623 8 p.

Research output: Contribution to journal › Article

20 Scopus citations

18F-Labeled Benzamides for Studying the Dopamine D2 Receptor with Positron Emission Tomography

Mach, R. H., Luedtke, R. R., Unsworth, C. D., Boundy, V. A., Nowak, P. A., Scripko, J. G., Elder, S. T., Jackson, J. R., Hoffman, P. L., Evora, P. H., Rao, A. V., Molinoff, P. B., Childers, S. R. & Ehrenkaufer, R. L., 1 Jan 1993, In : Journal of Medicinal Chemistry. 36, 23, p. 3707-3720 14 p.

Research output: Contribution to journal › Article

57 Scopus citations

1985 volvo award in clinical sciences objective assessment of spine function following industrial injury a prospective study with comparison group and one-year follow-up

Mayer, T. G., Gatchel, R. J., Kishino, N., Keeley, J., Capra, P., Mayer, H., Barnett, J. & Mooney, V., 1 Jan 1985, In : Spine. 10, 6, p. 482-493 12 p.

Research output: Contribution to journal › Article

449 Scopus citations

2019 united states osteopathic medical regulatory summit: Consensus, recommendations, and next steps in defining osteopathic distinctiveness

Gimpel, J. R., Belanger, S. I., Knebl, J. A., Labaere, R. J., Shaffer, D. C., Shannon, S. C., Shears, T., Steingard, S. A., Turner, M. D. & Williams, D. G., 1 Jan 2020, In : Journal of the American Osteopathic Association. 120, 1, p. 35-44 10 p.

Research output: Contribution to journal › Article

21st Birthday Celebratory Drinking: Evaluation of a Personalized Normative Feedback Card Intervention

Lewis, M. A., Neighbors, C., Lee, C. M. & Oster-Aaland, L., 1 Jun 2008, In : Psychology of Addictive Behaviors. 22, 2, p. 176-185 10 p.

Research output: Contribution to journal › Article

35 Scopus citations

25 X 2030: Anticipating the impact

Galke, C. & Clements, D. S., 1 May 2019, In : Annals of family medicine. 17, 3, p. 277-278 2 p.

Research output: Contribution to journal › Article

Open Access
1 Scopus citations

2-Amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] -phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase

Porchia, L. M., Guerra, M., Wang, Y-C., Zhang, Y., Espinosa, A. V., Shinohara, M., Kulp, S. K., Kirschner, L. S., Saji, M., Chen, C. S. & Ringel, M. D., 1 Nov 2007, In : Molecular Pharmacology. 72, 5, p. 1124-1131 8 p.

Research output: Contribution to journal › Article

60 Scopus citations

2B4, a new member of the immunoglobulin gene superfamily, is expressed on murine dendritic epidermal T cells and plays a functional role in their killing of skin tumors

Schuhmachers, G., Ariizumi, K., Mathew, P. A., Bennett, M., Kumar, V. & Takashima, A., 1 Jan 1995, In : Journal of Investigative Dermatology. 105, 4, p. 592-596 5 p.

Research output: Contribution to journal › Article

52 Scopus citations

2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48

Brown, M. H., Boles, K., Van Der Merwe, P. A., Kumar, V., Mathew, P. A. & Barclay, A. N., 7 Dec 1998, In : Journal of Experimental Medicine. 188, 11, p. 2083-2090 8 p.

Research output: Contribution to journal › Article

332 Scopus citations

2B4 (CD244)-mediated activation of cytotoxicity and IFN-γ release in human NK cells involves distinct pathways

Chuang, S. S., Kumaresan, P. R. & Mathew, P. A., 1 Dec 2001, In : Journal of Immunology. 167, 11, p. 6210-6216 7 p.

Research output: Contribution to journal › Article

Open Access
94 Scopus citations

2B4(CD244)-Mediated Activation of NK Cells Reduces Metastases of B16F10 Melanoma in Mice

Johnson, L. A., Vaidya, S. V., Goldfarb, R. H. & Mathew, P. A., 1 Sep 2003, In : Anticancer Research. 23, 5 A, p. 3651-3655 5 p.

Research output: Contribution to journal › Article

5 Scopus citations

2B4+ CD8+ T cells play an inhibitory role against constrained HIV epitopes

Aldy, K. N., Horton, N. C., Mathew, P. & Mathew, S. O., 18 Feb 2011, In : Biochemical and Biophysical Research Communications. 405, 3, p. 503-507 5 p.

Research output: Contribution to journal › Article

17 Scopus citations

2B4 Acts As a Non-Major Histocompatibility Complex Binding Inhibitory Receptor on Mouse Natural Killer Cells

Lee, K. M., McNerney, M. E., Stepp, S. E., Mathew, P. A., Schatzle, J. D., Bennett, M. & Kumar, V., 3 May 2004, In : Journal of Experimental Medicine. 199, 9, p. 1245-1254 10 p.

Research output: Contribution to journal › Article

158 Scopus citations

2B4 stimulation of YT cells induces natural killer cell cytolytic function and invasiveness

Chuang, S. S., Kim, M. H., Johnson, L. A., Albertsson, P., Kitson, R. P., Nannmark, U., Goldfarb, R. H. & Mathew, P. A., 24 Jul 2000, In : Immunology. 100, 3, p. 378-383 6 p.

Research output: Contribution to journal › Article

43 Scopus citations

2D SMARTCyp reactivity-based site of metabolism prediction for major drug-metabolizing cytochrome P450 enzymes

Liu, R., Liu, J., Tawa, G. & Wallqvist, A., 25 Jun 2012, In : Journal of Chemical Information and Modeling. 52, 6, p. 1698-1712 15 p.

Research output: Contribution to journal › Article

20 Scopus citations

2-GHz frequency-domain fluorometer

Lakowicz, J. R., Laczko, G. & Gryczynski, I., 1 Dec 1986, In : Review of Scientific Instruments. 57, 10, p. 2499-2506 8 p.

Research output: Contribution to journal › Article

187 Scopus citations

2nd International Symposium on Reverse Cholesterol Transport: Report on a meeting

Lacko, A. G. & Pritchard, P. H., 1 Jan 1994, In : Journal of Lipid Research. 35, 2, p. 351-356 6 p.

Research output: Contribution to journal › Article

3 Scopus citations

2′-Hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma

Nagaprashantha, L. D., Vatsyayan, R., Singhal, J., Lelsani, P., Prokai, L., Awasthi, S. & Singhal, S. S., 1 Apr 2011, In : Carcinogenesis. 32, 4, p. 568-575 8 p.

Research output: Contribution to journal › Article

28 Scopus citations

3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu 5: Identification of easily prepared tool compounds with CNS exposure in rats

Felts, A. S., Lindsley, S. R., Lamb, J. P., Rodriguez, A. L., Menon, U. N., Jadhav, S., Jones, C. K., Conn, P. J., Lindsley, C. W. & Emmitte, K. A., 1 Aug 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 15, p. 4390-4394 5 p.

Research output: Contribution to journal › Article

18 Scopus citations

3D-model of adult cardiac stem cells promotes cardiac differentiation and resistance to oxidative stress

Bartosh, T. J., Wang, Z., Rosales, A. A., Dan Dimitrijevich, S. & Roque, R. S., 1 Oct 2008, In : Journal of Cellular Biochemistry. 105, 2, p. 612-623 12 p.

Research output: Contribution to journal › Article

46 Scopus citations

3D spatially-adaptive canonical correlation analysis: Local and global methods

Yang, Z., Zhuang, X., Sreenivasan, K., Mishra, V., Curran, T., Byrd, R., Nandy, R. & Cordes, D., 1 Apr 2018, In : NeuroImage. 169, p. 240-255 16 p.

Research output: Contribution to journal › Article

3 Scopus citations

49,000 avocado cutting injuries

Rossheim, M. E., Ninh, E. Q., Livingston, M. D. & Thombs, D. L., 1 Jan 2020, In : American Journal of Health Behavior. 44, 1, p. 13-17 5 p.

Research output: Contribution to journal › Article

4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway

Chaudhary, P., Sharma, R., Sahu, M., Vishwanatha, J. K., Awasthi, S. & Awasthi, Y. C., 12 Jul 2013, In : Journal of Biological Chemistry. 288, 28, p. 20532-20546 15 p.

Research output: Contribution to journal › Article

35 Scopus citations

4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells

Sharma, A., Sharma, R., Chaudhary, P., Vatsyayan, R., Pearce, V., Jeyabal, P. V. S., Zimniak, P., Awasthi, S. & Awasthi, Y. C., 15 Dec 2008, In : Archives of Biochemistry and Biophysics. 480, 2, p. 85-94 10 p.

Research output: Contribution to journal › Article

62 Scopus citations

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

Venkatesan, A. M., Agarwal, A., Abe, T., Ushirogochi, H., Ado, M., Tsuyoshi, T., Dos Santos, O., Li, Z., Francisco, G., Lin, Y. I., Petersen, P. J., Yang, Y., Weiss, W. J., Shlaes, D. M. & Mansour, T. S., 15 Feb 2008, In : Bioorganic and Medicinal Chemistry. 16, 4, p. 1890-1902 13 p.

Research output: Contribution to journal › Article

50 Scopus citations

5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

McCracken, S., Fong, N., Rosonina, E., Yankulov, K., Brothers, G., Siderovski, D., Hessel, A., Foster, S., Shuman, S. & Bentley, D. L., 15 Dec 1997, In : Genes and Development. 11, 24, p. 3306-3318 13 p.

Research output: Contribution to journal › Article

Open Access
403 Scopus citations

5-HTTLPR genotype and associations with intoxication and intention to drive: Results from a field study of bar patrons

Thombs, D. L., O'Mara, R. J., Hou, W., Wagenaar, A. C., Dong, H. J., Merves, M. L., Goldberger, B. A., Weiler, R. M., Dodd, V. J. & Clapp, J. D., 1 Jan 2011, In : Addiction Biology. 16, 1, p. 133-141 9 p.

Research output: Contribution to journal › Article

6 Scopus citations