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  • Riyaz Basha

Adiponectin: Its role in obesity-associated colon and prostate cancers

Muppala, S., Konduru, S. K. P., Merchant, N., Ramsoondar, J., Rampersad, C. K., Rajitha, B., Mukund, V., Kancherla, J., Hammond, A., Barik, T. K., Mannarapu, M., Alam, A., Basha, R., Bramhachari, P. V., Verma, D., Sushma, P. S., Pattnaik, S. & Nagaraju, G. P., 1 Aug 2017, In : Critical Reviews in Oncology/Hematology. 116, p. 125-133 9 p.

Research output: Contribution to journalReview article

20 Scopus citations
Open Access
3 Scopus citations

Anticancer activity of tolfenamic acid in medulloblastoma: A preclinical study

Eslin, D., Lee, C., Sankpal, U. T., Maliakal, P., Sutphin, R. M., Abraham, L. & Basha, R. M., 20 May 2013, In : Tumor Biology. 34, 5, p. 2781-2789 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Anti-leukemic response of a NSAID, tolfenamic acid

Sutphin, R. M., Connelly, S. F., Lee, C. M., Sankpal, U. T., Eslin, D., Khan, M., Pius, H. & Basha, R., Jun 2014, In : Targeted Oncology. 9, 2, p. 135-144 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Aquaporins: Their role in gastrointestinal malignancies

Nagaraju, G. P., Basha, R., Rajitha, B., Alese, O. B., Alam, A., Pattnaik, S. & El-Rayes, B., 1 Apr 2016, In : Cancer Letters. 373, 1, p. 12-18 7 p.

Research output: Contribution to journalShort survey

23 Scopus citations

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation

Sankpal, U. T., Ingersoll, S. B., Ahmad, S., Holloway, R. W., Bhat, V. B., Simecka, J. W., Daniel, L., Kariali, E., Vishwanatha, J. K. & Basha, R., 1 Oct 2016, In : Tumor Biology. 37, 10, p. 14259-14269 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: A pre-clinical evaluation

Sankpal, U. T., Lee, C. M., Connelly, S. F., Kayaleh, O., Eslin, D., Sutphin, R., Goodison, S., Adwan, L., Zawia, N. H., Lichtenberger, L. M. & Basha, R., 1 Jan 2013, In : Cellular Physiology and Biochemistry. 32, 3, p. 675-686 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats

Maliakal, P., Abdelrahim, M., Sankpal, U. T., Maliakal, C., Baker, C. H., Safe, S., Herrera, L. J., Abudayyeh, A., Kaja, S. & Basha, R., 1 Jun 2012, In : Investigational New Drugs. 30, 3, p. 853-861 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, W. P., Simecka, J. W., Raut, S., Ray, A. & Basha, R., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

Shelake, S., Eslin, D., Sutphin, R. M., Sankpal, U. T., Wadwani, A., Kenyon, L. E., Tabor-Simecka, L., Bowman, W. P., Vishwanatha, J. K. & Basha, R., 1 Nov 2015, In : International Journal of Developmental Neuroscience. 46, p. 92-99 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combination of Tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

Sankpal, U. T., Nagaraju, G. P., Gottipolu, S. R., Hurtado, M., Jordan, C. G., Simecka, J. W., Shoji, M., El-Rayes, B. & Basha, R., 1 Jan 2016, In : Oncotarget. 7, 3, p. 3186-3200 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Correlation of Lipid Profile and Risk of Developing Type 2 Diabetes Mellitus in 10-14 Year Old Children

Habiba, N. M., Fulda, K. G., Basha, R., Shah, D., Fernando, S., Nguyen, B., Xiong, Y., Franks, S. F., Matches, S. J., Magie, R. D. & Bowman, W. P., 1 Nov 2016, In : Cellular Physiology and Biochemistry. 39, 5, p. 1695-1704 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Defining early life stress as a precursor for autoimmune disease

Choe, J. Y., Nair, M., Basha, R., Kim, B. J. & Jones, H. P., 1 Jan 2019, In : Critical Reviews in Immunology. 39, 5, p. 329-342 14 p.

Research output: Contribution to journalArticle

Developmental Arsenic Exposure: Behavioral Dysfunctions and Neurochemical Perturbations

Basha, R. & Reddy, G. R., 8 Jan 2015, Handbook of Arsenic Toxicology. Elsevier Inc., p. 443-457 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Diversity in the era of precision medicine - From bench to bedside implementation

Mamun, A., Nsiah, N. Y., Srinivasan, M., Chaturvedula, A., Basha, R., Cross, D., Jones, H. P., Nandy, K. & Vishwanatha, J. K., 1 Jan 2019, In : Ethnicity and Disease. 29, 3, p. 517-524 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Editorial contemporary approaches in cancer therapy

Basha, R., 1 Sep 2011, In : Medicinal chemistry. 7, 5, p. 430-431 2 p.

Research output: Contribution to journalEditorial

Environmental factors in causing human cancers: Emphasis on tumorigenesis

Sankpal, U. T., Pius, H., Khan, M., Shukoor, M. I., Maliakal, P., Lee, C. M., Abdelrahim, M., Connelly, S. F. & Basha, R. M., 1 Oct 2012, In : Tumor Biology. 33, 5, p. 1265-1274 10 p.

Research output: Contribution to journalReview article

41 Scopus citations

Evidence-based approaches to reduce cancer health disparities: Discover, develop, deliver, and disseminate

Desai, P. P., Lampe, J. B., Bakre, S. A., Basha, R. M., Jones, H. P. & Vishwanatha, J. K., 1 Jan 2018, In : Journal of Carcinogenesis. 17, 1, 17.

Research output: Contribution to journalArticle

Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy

Sankpal, U. T., Maliakal, P., Bose, D., Kayaleh, O., Buchholz, D. & Basha, R. M., 1 Aug 2012, In : Current Medicinal Chemistry. 19, 22, p. 3779-3786 8 p.

Research output: Contribution to journalReview article

24 Scopus citations

Impact of the microbiome on the immune system

Lambring, C. B., Siraj, S., Patel, K., Sankpal, U. T., Mathew, S. & Basha, R., 1 Jan 2019, In : Critical Reviews in Immunology. 39, 5, p. 313-328 16 p.

Research output: Contribution to journalArticle

Investigational agents to enhance the efficacy of chemotherapy or radiation in pancreatic cancer

Hurtado, M., Sankpal, U. T., Ranjan, A., Maram, R., Vishwanatha, J. K., Nagaraju, G. P., El-Rayes, B. F. & Basha, R., Jun 2018, In : Critical Reviews in Oncology/Hematology. 126, p. 201-207 7 p.

Research output: Contribution to journalReview article

9 Scopus citations

Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer

Nair, V., Sreevalsan, S., Basha, R., Abdelrahlm, M., Abudayyeh, A., Hoffman, A. R. & Safe, S., 3 Oct 2014, In : Journal of Biological Chemistry. 289, 40, p. 27692-27701 10 p.

Research output: Contribution to journalArticle

67 Scopus citations

Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors

Nair, V., Pathi, S., Jutooru, I., Sreevalsan, S., Basha, R., Abdelrahim, M., Samudio, I. & Safe, S., 1 Dec 2013, In : Carcinogenesis. 34, 12, p. 2870-2879 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Methyl 2-cyano-3,12-dioxooleana-1, 9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: Role of microRNA-27a (Molecular Pharmacology (2010) 78, (226-236))

Jutooru, I., Chadalapaka, G., Abdelrahim, M., Basha, M. R., Samudio, I., Konopleva, M., Andreeff, M. & Safe, S., 1 Feb 2011, In : Molecular Pharmacology. 79, 2, 1 p.

Research output: Contribution to journalComment/debate

Molecular tools in cancer diagnosis and therapy

Basha, R. M., 1 Aug 2012, In : Current Medicinal Chemistry. 19, 22, p. 3651-3652 2 p.

Research output: Contribution to journalEditorial

Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells

Hurtado, M., Prokai, L., Sankpal, U. T., Levesque, B., Maram, R., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K. & Basha, R., Feb 2020, In : Process Biochemistry. 89, p. 155-164 10 p.

Research output: Contribution to journalArticle

Novel survivin inhibitor for suppressing pancreatic cancer cells growth via downregulating Sp1 and Sp3 transcription factors

Hurtado, M., Sankpal, U. T., Kaba, A., Mahammad, S., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K. & Basha, R., 1 Dec 2018, In : Cellular Physiology and Biochemistry. 51, 4, p. 1894-1907 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ovarian cancer: Current status and strategies for improving therapeutic outcomes

Chandra, A., Pius, C., Nabeel, M., Nair, M., Vishwanatha, J. K., Ahmad, S. & Basha, R., 1 Nov 2019, In : Cancer Medicine. 8, 16, p. 7018-7031 14 p.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Ovarian cancer and resistance to therapies: Clinical and laboratory perspectives

Basha, R. M., Mohiuddin, Z., Rahim, A. & Ahmad, S., 1 Jan 2017, Drug Resistance in Bacteria, Fungi, Malaria, and Cancer. Springer International Publishing, p. 511-537 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pancreatic cancer: An emphasis on current perspectives in immunotherapy

Patel, K., Siraj, S., Smith, C., Nair, M., Vishwanatha, J. K. & Basha, R., 1 Jan 2019, In : Critical Reviews in Oncogenesis. 24, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Proteomic Analysis of the Very Low Density Lipoprotein (VLDL) transport vesicles

Rahim, A., Nafi-valencia, E., Siddiqi, S., Basha, R., Runyon, C. C. & Siddiqi, S. A., 3 Apr 2012, In : Journal of Proteomics. 75, 7, p. 2225-2235 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Relevance of drug metabolizing enzyme activity modulation by tea polyphenols in the inhibition of esophageal tumorigenesis

Maliakal, P., Sankpal, U. T., Basha, R. M., Maliakal, C., Ledford, A. & Wanwimolruk, S., 1 Sep 2011, In : Medicinal chemistry. 7, 5, p. 480-487 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Response to Pazopanib in Patients with Relapsed Osteosarcoma

Elete, K. R., Albritton, K. H., Akers, L. J., Basha, R. M. & Ray, A., 1 Jan 2018, (Accepted/In press) In : Journal of Pediatric Hematology/Oncology.

Research output: Contribution to journalArticle

2 Scopus citations
22 Scopus citations

Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer

Sankpal, U. T., Abdelrahim, M., Connelly, S. F., Lee, C. M., Madero-Visbal, R., Colon, J., Smith, J., Safe, S., Maliakal, P. & Basha, R. M., 1 Nov 2012, In : Prostate. 72, 15, p. 1648-1658 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Targeted nanoparticles for pediatric leukemia therapy

Basha, R., Sabnis, N., Heym, K., Bowman, W. P. & Lacko, A. G., 1 Jan 2014, In : Frontiers in Oncology. 4 MAY, 101.

Research output: Contribution to journalReview article

14 Scopus citations

Targeting Sp1 transcription factor in prostate cancer therapy

Sankpal, U. T., Goodison, S., Abdelrahim, M. & Basha, R., 1 Sep 2011, In : Medicinal chemistry. 7, 5, p. 518-525 8 p.

Research output: Contribution to journalReview article

84 Scopus citations

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth

Shelake, S., Sankpal, U. T., Paul Bowman, W., Wise, M., Ray, A. & Basha, R., 1 Apr 2017, In : Investigational New Drugs. 35, 2, p. 158-165 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

The impact of curcumin on breast cancer

Nagaraju, G. P., Aliya, S., Zafar, S. F., Basha, R., Diaz, R. & El-Rayes, B. F., Sep 2012, In : Integrative Biology (United Kingdom). 4, 9, p. 996-1007 12 p.

Research output: Contribution to journalReview article

58 Scopus citations

Therapeutic applications of NSAIDS in cancer: Special emphasis on tolfenamic acid

Basha, R. M., Baker, C. T., Sankpal, U. T., Ahmad, S., Safe, S., Abbruzzese, J. L. & Abdelrahim, M., 1 Jan 2011, In : Frontiers in Bioscience - Scholar. 3 S, 2, p. 797-805 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice

Colon, J., Basha, R. M., Madero-Visbal, R., Konduri, S., Baker, C. H., Herrera, L. J., Safe, S., Sheikh-Hamad, D., Abudayyeh, A., Alvarado, B. & Abdelrahim, M., 1 Feb 2011, In : Investigational New Drugs. 29, 1, p. 41-51 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells

Sankpal, U. T., Goodison, S., Jones-Pauley, M., Hurtado, M., Zhang, F. & Basha, R., 1 Jan 2017, In : Oncotarget. 8, 9, p. 14593-14603 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: A novel therapeutic agent for neuroblastoma

Eslin, D., Sankpal, U. T., Lee, C., Sutphin, R. M., Maliakal, P., Currier, E., Sholler, G., Khan, M. & Basha, R., 1 May 2013, In : Molecular Carcinogenesis. 52, 5, p. 377-386 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors

Basha, R. M., Ingersoll, S. B., Sankpal, U. T., Ahmad, S., Baker, C. H., Edwards, J. R., Holloway, R. W., Kaja, S. & Abdelrahim, M., 1 Jul 2011, In : Gynecologic Oncology. 122, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Tolfenamic Acid Interrupts the De Novo Synthesis of the β-Amyloid Precursor Protein and Lowers Amyloid Beta Via a Transcriptional Pathway

Adwan, L. I., Basha, R. M., Abdelrahim, M., Subaiea, G. M. & Zawia, N. H., 1 Jun 2011, In : Current Alzheimer Research. 8, 4, p. 385-392 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Tolfenamic acid reduces tau and CDK5 levels: Implications for dementia and tauopathies

Adwan, L., Subaiea, G. M., Basha, R. & Zawia, N. H., 1 Apr 2015, In : Journal of Neurochemistry. 133, 2, p. 266-272 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver

Siddiqi, S. A., Shukoor, M. I., Tiwari, S., Sankpal, U. T., Maliakal, P., Connelly, S. F., Siddiqi, S. & Basha, R., Sep 2012, In : Integrative Biology (United Kingdom). 4, 9, p. 1122-1129 8 p.

Research output: Contribution to journalArticle

5 Scopus citations