Find Research Outputs

2019

Evidence of hypoxic glial cells in a model of ocular hypertension

Jassim, A. H. & Inman, D. M., 1 Jan 2019, In : Investigative Ophthalmology and Visual Science. 60, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
Ocular Hypertension
Optic Nerve Diseases
Neuroglia
Astrocytes
Glutathione

Examining the Influence of Religious and Spiritual Beliefs on HPV Vaccine Uptake Among College Women

Best, A. L., Thompson, E. L., Adamu, A. M., Logan, R., Delva, J., Thomas, M., Cunningham, E., Vamos, C. & Daley, E., 1 Jan 2019, In : Journal of Religion and Health.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Religion
Vaccination
Sexual Behavior
Spirituality
5 Citations (Scopus)

Exosomes derived from bone mesenchymal stem cells ameliorate early inflammatory responses following traumatic brain injury

Ni, H., Yang, S., Siaw-Debrah, F., Hu, J., Wu, K., He, Z., Yang, J., Pan, S., Lin, X., Ye, H., Xu, Z., Wang, F., Jin, K., Zhuge, Q. & Huang, L., 1 Jan 2019, In : Frontiers in Neuroscience. 13, JAN, 14.

Research output: Contribution to journalArticle

Open Access
Exosomes
Mesenchymal Stromal Cells
Bone and Bones
Microglia
Macrophages
Microsatellite Repeats
Alleles
DNA
Forensic Genetics
Population Genetics
2 Citations (Scopus)

Experimental ischemic stroke induces long-term T cell activation in the brain

Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S. H., 1 Nov 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 11, p. 2268-2276 9 p.

Research output: Contribution to journalArticle

Stroke
T-Lymphocytes
Brain
Perforin
Interleukin-17

Exploring the 1000 Genomes Project haplotype reporting for the CYP2D6 pharmacogene

Wendt, F. R., Woerner, A. E., Sajantila, A., Moura-Neto, R. S. & Budowle, B., 1 May 2019, In : International journal of legal medicine. 133, 3, p. 807-810 4 p.

Research output: Contribution to journalLetter

Cytochrome P-450 CYP2D6
Haplotypes
Genome
1 Citation (Scopus)
Open Access
Ankyrins
Solitary Nucleus
navigation technology satellites
Ion Channels
nuclei
1 Citation (Scopus)

Forensic human identification with targeted microbiome markers using nearest neighbor classification

Woerner, A. E., Novroski, N. M. M., Wendt, F. R., Ambers, A. D., Wiley, R., Schmedes, S. E. & Budowle, B., 1 Jan 2019, In : Forensic Science International: Genetics. 38, p. 130-139 10 p.

Research output: Contribution to journalArticle

Forensic Anthropology
Microbiota
Forensic Genetics
Population Genetics
Phylogeny

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Mar 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein

Genistein: mechanisms of action for a pleiotropic neuroprotective agent in stroke

Schreihofer, D. & Oppong-Gyebi, A., 3 Jun 2019, In : Nutritional Neuroscience. 22, 6, p. 375-391 17 p.

Research output: Contribution to journalArticle

Genistein
Neuroprotective Agents
Stroke
Estrogens
Brain Injuries

GFR-α1 Expression in Substantia Nigra Increases Bilaterally following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss following 6-OHDA Nigrostriatal Lesion

Kasanga, E. A., Owens, C. L., Cantu, M. A., Richard, A. D., Davis, R. W., McDivitt, L. M., Blancher, B., Pruett, B. S., Tan, C., Gajewski, A., Manfredsson, F. P., Nejtek, V. A. & Salvatore, M. F., 16 Oct 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4237-4249 13 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Corpus Striatum
Oxidopamine
Tyrosine 3-Monooxygenase
Substantia Nigra

Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease

Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In : Neuroscience. 414, p. 8-27 20 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine 3-Monooxygenase
Parkinson Disease
Dopamine
3,4-Dihydroxyphenylacetic Acid

Global research initiatives to understand the prescription drug misuse epidemic and ways to monitor and intervene

Rickles, N. M., Fleming, M. L. & Björnsdottir, I., 1 Aug 2019, In : Research in Social and Administrative Pharmacy. 15, 8, p. 907-909 3 p.

Research output: Contribution to journalEditorial

Prescription Drug Misuse
Prescription Drugs
Research

Glucagon-like peptide-1 receptor pathway inhibits extracellular matrix production by mesangial cells through store-operated Ca2+ channel

Huang, L., Ma, R., Lin, T., Chaudhari, S., Shotorbani, P. Y., Yang, L. & Wu, P., 1 Oct 2019, In : Experimental Biology and Medicine. 244, 14, p. 1193-1201 9 p.

Research output: Contribution to journalArticle

Open Access
Mesangial Cells
Extracellular Matrix
Extracellular Matrix Proteins
Glucose
Fibronectins
1 Citation (Scopus)
Open Access
Ocular Hypertension
Trabecular Meshwork
Glucocorticoid Receptors
Glaucoma
Transcriptional Activation

Group-based trajectory models to identify sociodemographic and clinical predictors of adherence patterns to statin therapy among older adults

Vadhariya, A., Fleming, M. L., Johnson, M. L., Essien, E. J., Serna, O., Esse, T., Choi, J., Boklage, S. H. & Abughosh, S. M., 1 Jun 2019, In : American Health and Drug Benefits. 12, 4, p. 202-211 10 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Medicare Part C
Therapeutics
Medication Adherence
Therapy
Open Access
Sexual Behavior
Drinking
Young Adult
Alcohols
Research

Head-Eye Coordination of Humanoid Robot with Potential Controller

Wijayasinghe, I. B., Das, S. K., Miller, H. L., Bugnariu, N. & Popa, D. O., 15 Apr 2019, In : Journal of Intelligent and Robotic Systems: Theory and Applications. 94, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

Robots
Controllers
Robotics
Anthropomorphic robots
Eye movements
1 Citation (Scopus)

HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis

Laureano-Phillips, J., Robinson, R. D., Aryal, S., Blair, S., Wilson, D., Boyd, K., Schrader, C. D., Zenarosa, N. R. & Wang, H., 1 Aug 2019, In : Annals of Emergency Medicine. 74, 2, p. 187-203 17 p.

Research output: Contribution to journalReview article

Troponin
Age Factors
Chest Pain
Meta-Analysis
Hospital Emergency Service

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

Lower Body Negative Pressure
Oxidative stress
Young Adult
Oxidative Stress
Hemorrhage

Higher Reliance on Glycolysis Limits Glycolytic Responsiveness in Degenerating Glaucomatous Optic Nerve

Jassim, A. H., Coughlin, L., Harun-Or-Rashid, M., Kang, P. T., Chen, Y. R. & Inman, D. M., 1 Oct 2019, In : Molecular Neurobiology. 56, 10, p. 7097-7112 16 p.

Research output: Contribution to journalArticle

Open Access
Glycolysis
Optic Nerve
Glaucoma
Oxygen Consumption
Respiration

High-risk adolescents’ sexuality education preferences based on Hispanic ethnicity

Maness, S. B., Wilson, K. L., Thompson, E. L., Rosen, B. L. & Zingg, T., 1 Jan 2019, In : Sex Education.

Research output: Contribution to journalArticle

adolescent sexuality
ethnicity
adolescent
pregnancy
education

Homozygous rare Parn missense mutation in familial pulmonary fibrosis

Zhang, D., Zhou, Z., Abu-Hijleh, M., Batra, K., Xing, C. & Garcia, C. K., 15 Mar 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 6, p. 797-799 3 p.

Research output: Contribution to journalLetter

Pulmonary Fibrosis
Missense Mutation

How Is Health Literacy Related to Pap Testing Among US Women?

Thompson, E. L., Wheldon, C. W., Vamos, C. A., Griner, S. B. & Daley, E. M., 15 Aug 2019, In : Journal of Cancer Education. 34, 4, p. 789-795 7 p.

Research output: Contribution to journalArticle

Health Literacy
Uterine Cervical Neoplasms
Papanicolaou Test
Logistic Models
Sexually Transmitted Diseases

Human papillomavirus risk perceptions and relationship status: a barrier to HPV vaccination?

Thompson, E. L., Vamos, C. A., Piepenbrink, R., Kadono, M., Vázquez-Otero, C., Matthes, S. & Daley, E. M., 1 Oct 2019, In : Journal of Behavioral Medicine. 42, 5, p. 991-997 7 p.

Research output: Contribution to journalArticle

Vaccination
Young Adult
Logistic Models
Papillomavirus Vaccines
Women's Rights
2 Citations (Scopus)

Human Papillomavirus Vaccination and School Entry Requirements: Politically Challenging, but Not Impossible

Daley, E., Thompson, E. L. & Zimet, G., 1 Jan 2019, In : JAMA Pediatrics. 173, 1, p. 6-7 2 p.

Research output: Contribution to journalComment/debate

Vaccination

Human trafficking – Multinational challenge for forensic science

Buś, M. M., Schellberg, T. & Budowle, B., 1 Jan 2019, (Accepted/In press) In : Forensic Science International: Genetics Supplement Series.

Research output: Contribution to journalArticle

Human Trafficking
Forensic Sciences
Forensic Anthropology
DNA
Databases

Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death

Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., 1 Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.

Research output: Contribution to journalArticle

Open Access
Retinal Ganglion Cells
Cell Death
Nerve Crush
Animal Models
Retina
1 Citation (Scopus)

Identification of Binding Sites for Efflux Pump Inhibitors of the AcrAB-TolC Component AcrA

Darzynkiewicz, Z. M., Green, A. T., Abdali, N., Hazel, A., Fulton, R. L., Kimball, J., Gryczynski, Z., Gumbart, J. C., Parks, J. M., Smith, J. C. & Zgurskaya, H. I., 19 Feb 2019, In : Biophysical Journal. 116, 4, p. 648-658 11 p.

Research output: Contribution to journalArticle

Binding Sites
Fluorescence Spectrometry
Molecular Dynamics Simulation
Site-Directed Mutagenesis
Gram-Negative Bacteria

Identification of long non-coding RNA-related and -coexpressed mRNA biomarkers for hepatocellular carcinoma

Zhang, F., Ding, L., Cui, L., Barber, R. & Deng, B., 31 Jan 2019, In : BMC Medical Genomics. 12, 25.

Research output: Contribution to journalArticle

Long Noncoding RNA
Hepatocellular Carcinoma
Biomarkers
Messenger RNA
Neoplasms

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S. L., Sabnis, N., Kong, X., Yang, X., Lopez-Berestein, G., Lacko, A. G. & Sood, A. K., 15 Aug 2019, In : Oncogene. 38, 33, p. 6095-6108 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Ovarian Neoplasms
Neoplasms
CD36 Antigens
Vascular Endothelial Growth Factor A
Open Access
Arousal
Emotions
Homeless Persons
Mental Health
Exercise

Immunological responses to the relapsing fever spirochete borrelia turicatae in infected rhesus macaques: Implications for pathogenesis and diagnosis

Embers, M. E., Krishnavajhala, A., Armstrong, B. A., Curtis, M. W., Pahar, B., Wilder, H. K., Allen, M. S., Beare, P. A., Hasenkampf, N. R. & Lopez, J. E., 1 Apr 2019, In : Infection and Immunity. 87, 4, e00900.

Research output: Contribution to journalArticle

Relapsing Fever
Borrelia
Spirochaetales
Macaca mulatta
Primates

Impact of a low-cost simulated electronic medical record on perceptions of APPE readiness

Gibson, C. M., Kwon, H. I. & Tatachar, A. V., 1 Jul 2019, In : Currents in Pharmacy Teaching and Learning. 11, 7, p. 736-741 6 p.

Research output: Contribution to journalArticle

Electronic medical equipment
Electronic Health Records
Students
Costs and Cost Analysis
Pharmacy Students

Impact of an electronic medium delivery of warfarin education in a low income, minority outpatient population: A pilot intervention study

Heinrich, K., Sanchez, K., Hui, C., Talabi, K., Perry, M., Qin, H., Nguyen, H. & Tatachar, A. V., 5 Aug 2019, In : BMC Public Health. 19, 1, 1050.

Research output: Contribution to journalArticle

Open Access
Warfarin
Outpatients
Education
Population
Patient Education

Impact of environmental stressors on tolerance to hemorrhage in humans

Crandall, C. G., Rickards, C. A. & Johnson, B. D., 1 Feb 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 2, p. R88-R100

Research output: Contribution to journalReview article

Lower Body Negative Pressure
Hemorrhage
Altitude Sickness
Hypovolemia
Military Personnel
1 Citation (Scopus)

Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework

Wu, R. R., Myers, R. A., Sperber, N., Voils, C. I., Neuner, J., McCarty, C. A., Haller, I. V., Harry, M., Fulda, K. G., Cross, D. S., Dimmock, D., Rakhra-Burris, T., Buchanan, A. H., Ginsburg, G. S. & Orlando, L. A., 1 Feb 2019, In : Genetics in Medicine. 21, 2, p. 331-338 8 p.

Research output: Contribution to journalArticle

Medical History Taking
Primary Health Care
Family Health
Clinical Decision Support Systems
Delivery of Health Care

Improvement in mental health following total hip arthroplasty: The role of pain and function

Nguyen, U. D. T., Perneger, T., Franklin, P. D., Barea, C., Hoffmeyer, P. & Lübbeke, A., 29 Jun 2019, In : BMC Musculoskeletal Disorders. 20, 1, 307.

Research output: Contribution to journalArticle

Open Access
Arthroplasty
Hip
Mental Health
Pain
Ontario

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., 1 Jan 2019, (Accepted/In press) In : Progress in Retinal and Eye Research. 100799.

Research output: Contribution to journalArticle

Glaucoma
Rodentia
Pressure
Intraocular Pressure
Low Tension Glaucoma

Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats

Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., 1 Jul 2019, In : Neurochemistry International. 127, p. 64-72 9 p.

Research output: Contribution to journalArticle

Autophagy
Stroke
Middle Cerebral Artery Infarction
Young Adult
Up-Regulation

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Yurvati, A., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., 1 May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journalArticle

Open Access
Ventriculoperitoneal Shunt
Cerebrospinal Fluid
Swine
Hydrocephalus
Cerebrospinal fluid

Intracranial atherosclerotic disease

Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., 1 Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.

Research output: Contribution to journalArticle

Intracranial Arteriosclerosis
Stroke
Therapeutics
Recurrence
Risk Management

In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection

Weiss, W., Pulse, M. E., Nguyen, P. & Growcott, E. J., 1 Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e02214-18.

Research output: Contribution to journalArticle

Klebsiella Infections
Monobactams
Carbapenems
Klebsiella pneumoniae
Uranyl Nitrate
Cell membranes
Brain
Coloring Agents
Dyes
Nanoparticles

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Exercise
Clinical Trials
Hypoxia-Inducible Factor 1
Microglia

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D 3 Receptor (D 3 R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)

Reilly, S. W., Riad, A. A., Hsieh, C. J., Sahlholm, K., Jacome, D. A., Griffin, S., Taylor, M., Weng, C. C., Xu, K., Kirschner, N., Luedtke, R. T., Parry, C., Malhotra, S., Karanicolas, J. & Mach, R. H., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5132-5147 16 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Dopamine
Ligands
Adrenergic Agents
Pharmaceutical Preparations

Limited Intragenerational Mobility of Surgical Caseload of Iowa Hospitals

O'Neill, L., Dexter, F. & Epstein, R. H., 1 Jul 2019, In : Journal of Medical Systems. 43, 7, 187.

Research output: Contribution to journalArticle

Least-Squares Analysis
Economics
Statistics
Growth

Linkage, recombination, and mutation rate analyses of 19 X-chromosomal STR loci in Chinese Southern Han pedigrees

Yang, X., Chen, Y., Zeng, X., Chen, L., Liu, C., Liu, H., Xu, Q., Budowle, B. & Liu, C., 1 Nov 2019, In : International journal of legal medicine. 133, 6, p. 1691-1698 8 p.

Research output: Contribution to journalArticle

Linkage Disequilibrium
Mutation Rate
Pedigree
Genetic Recombination
Haplotypes
Locomotion
N-Methyl-3,4-methylenedioxyamphetamine
Rats
Methamphetamine
Cocaine
Microsatellite Repeats
Technology
Alleles
Rubiaceae
Tandem Repeat Sequences