Find Research Outputs

2019
Open Access
Retinal Ganglion Cells
Glaucoma
Publications
Cell Death
Animal Models
Open Access
National Institute of Neurological Disorders and Stroke
Organized Financing
Astrocytes
Histones
Methylation

Development and Validation of an Algorithm to Classify as Equivalent the Procedures in ICD-10-PCS That Differ Only by Laterality

Epstein, R. H., Dexter, F. & O'Neill, L., 1 Jun 2019, In : Anesthesia and analgesia. 128, 6, p. 1138-1144 7 p.

Research output: Contribution to journalArticleResearchpeer-review

International Classification of Diseases
Inpatients
Language
Operative Surgical Procedures
Confidence Intervals

Development of a motivational interviewing genetic counseling intervention to increase cascade cholesterol screening in families of children with familial hypercholesterolemia

Kruger, V., Redlinger-Grosse, K., Walters, S. T., Ash, E., Cragun, D., McCarthy Veach, P. & Zierhut, H. A., 1 Jan 2019, In : Journal of Genetic Counseling.

Research output: Contribution to journalArticleResearchpeer-review

Motivational Interviewing
Hyperlipoproteinemia Type II
Genetic Engineering
Health Behavior
Genetic Counseling

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), 1 Jul 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Apolipoprotein E4
Amyloid
Alzheimer Disease
Brain
Frontal Lobe
1 Citation (Scopus)

Differential effects of protein kinase C-eta on apoptosis versus senescence

Basu, A., Pal, D. & Blaydes, R., 1 Mar 2019, In : Cellular Signalling. 55, p. 1-7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Apoptosis
Doxorubicin
Breast Neoplasms
protein kinase C eta
Galactosidases

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

d’Oliveira, G. D. C., Custodio, J. M. F., Moura, A. F., Napolitano, H. B., Pérez, C. N., Moraes, M. O., Prokai, L. & Perjési, P., 1 Sep 2019, In : Medicinal Chemistry Research. 28, 9, p. 1448-1460 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Chalcones
Chalcone
Quinolones
Glutathione
Toxicity

Direct Oral Anticoagulants in Chronic Liver Disease

Steuber, T. D., Howard, M. & Nisly, S. A., 1 Oct 2019, In : Annals of Pharmacotherapy. 53, 10, p. 1042-1049 8 p.

Research output: Contribution to journalReview articleResearchpeer-review

Anticoagulants
Liver Diseases
Chronic Disease
Clinical Trials
Information Storage and Retrieval

Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

Felts, A. S., Bollinger, K. A., Brassard, C. J., Rodriguez, A. L., Morrison, R. D., Scott Daniels, J., Blobaum, A. L., Niswender, C. M., Jones, C. K., Jeffrey Conn, P., Emmitte, K. A. & Lindsley, C. W., 1 Jan 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 47-50 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Aldehyde Oxidase
Metabotropic Glutamate 5 Receptor
Metabotropic Glutamate Receptors
Metabolism
Modulators

Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 ) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores

Childress, E. S., Wieting, J. M., Felts, A. S., Breiner, M. M., Long, M. F., Luscombe, V. B., Rodriguez, A. L., Cho, H. P., Blobaum, A. L., Niswender, C. M., Emmitte, K. A., Conn, P. J. & Lindsley, C. W., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 378-384 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Rodentia
Central Nervous System
pyridine
pyrazolo(1,5-a)pyrimidine
metabotropic glutamate receptor 2

Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M 1 Positive Allosteric Modulators

Engers, J. L., Bender, A. M., Kalbfleisch, J. J., Cho, H. P., Lingenfelter, K. S., Luscombe, V. B., Han, C., Melancon, B. J., Blobaum, A. L., Dickerson, J. W., Rook, J. M., Niswender, C. M., Emmitte, K. A., Conn, P. J. & Lindsley, C. W., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1035-1042 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Lactams
Modulators
Cell Line
Muscarinic Receptors
Cells
3 Citations (Scopus)

Discovery of VU2957 (Valiglurax): An mGlu 4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease

Panarese, J. D., Engers, D. W., Wu, Y. J., Bronson, J. J., Macor, J. E., Chun, A., Rodriguez, A. L., Felts, A. S., Engers, J. L., Loch, M. T., Emmitte, K. A., Castelhano, A. L., Kates, M. J., Nader, M. A., Jones, C. K., Blobaum, A. L., Conn, P. J., Niswender, C. M., Hopkins, C. R. & Lindsley, C. W., 14 Mar 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 255-260 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Pulse amplitude modulation
Toxicology
Modulators
Parkinson Disease
Pharmacology

Does Current General Mental Health Status Relate to Current Smoking Status in Pregnant Women?

Liu, D., Younger, E., Baker, S., Touch, S., Willmoth, T. L. & Hartos, J. L., 1 Jan 2019, In : Journal of Pregnancy. 2019, 7801465.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Health Status
Pregnant Women
Mental Health
Smoking
Tobacco Use
1 Citation (Scopus)

Doing it for the money: The relationship between gambling and money attitudes among college students

Lostutter, T. W., Enkema, M., Schwebel, F., Cronce, J. M., Garberson, L. A., Ou, B., Lewis, M. A. & Larimer, M. E., 1 Jan 2019, In : Journal of gambling studies. 35, 1, p. 143-153 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Gambling
gambling
money
Students
student

Early career biomedical grantsmanship self-efficacy: validation of an abbreviated self-assessment tool

Harwood, E. M., Jones, A. R., Erickson, D., Buchwald, D., Johnson-Hemming, J., Jones, H., Manson, S., McGee, R., Smith, A., Steer, C. J., Vishwanatha, J. K., Weber-Main, A. M. & Okuyemi, K. S., 1 Jun 2019, In : Annals of the New York Academy of Sciences. 1445, 1, p. 17-26 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Self Efficacy
Organized Financing
Research Personnel
Research
Equipment and Supplies

Effect of coverage gap on healthcare utilization among Medicare beneficiaries with chronic obstructive pulmonary disorder

Sansgiry, S. S., Bhansali, A., Serna, O., Kamdar, M., Fleming, M. L., Abughosh, S. & Stanford, R. H., 1 Feb 2019, In : Current Medical Research and Opinion. 35, 2, p. 321-328 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Medicare
Hospitalization
Delivery of Health Care
Lung
Chronic Obstructive Pulmonary Disease

Effect of ocular hypertension on the pattern of retinal ganglion cell subtype loss in a mouse model of early-onset glaucoma

Daniel, S., Meyer, K. J., Clark, A., Anderson, M. G. & McDowell, C. M., 1 Aug 2019, In : Experimental eye research. 185, 107703.

Research output: Contribution to journalArticleResearchpeer-review

Ocular Hypertension
Retinal Ganglion Cells
Glaucoma
Intraocular Pressure
Phenotype

Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform

Wu, R. R., Myers, R. A., Buchanan, A. H., Dimmock, D., Fulda, K. G., Haller, I. V., Haga, S. B., Harry, M. L., McCarty, C., Neuner, J., Rakhra-Burris, T., Sperber, N., Voils, C. I., Ginsburg, G. S. & Orlando, L. A., 1 Jan 2019, In : Applied Clinical Informatics. 10, 2, p. 180-188 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Medical History Taking
Facings
Risk assessment
Information technology
Health

Effects of elastic band exercise on the frailty states in pre-frail elderly people

Chen, R., Wu, Q., Wang, D., Li, Z., Liu, H., Liu, G., Cui, Y. & Song, L., 1 Jan 2019, In : Physiotherapy Theory and Practice.

Research output: Contribution to journalArticleResearchpeer-review

Frail Elderly
Exercise
Hand Strength
Control Groups
Randomized Controlled Trials

Effects of salt-loading on supraoptic vasopressin neurones assessed by ClopHensorN chloride imaging

Balapattabi, K., Farmer, G. E., Knapp, B. A., Little, J. T., Bachelor, M., Yuan, J. P. & Cunningham, J. T., 1 Jan 2019, In : Journal of Neuroendocrinology. 31, 8, e12752.

Research output: Contribution to journalArticleResearchpeer-review

Supraoptic Nucleus
Vasopressins
Chlorides
Arginine Vasopressin
Salts
1 Citation (Scopus)

Effects of temperature on bacterial microbiome composition in Ixodes scapularis ticks

Thapa, S., Zhang, Y. & Allen, M. S., 1 May 2019, In : MicrobiologyOpen. 8, 5, e00719.

Research output: Contribution to journalArticleResearchpeer-review

Ixodes
Microbiota
Ticks
Temperature
Rickettsia

Efficacy and Safety of Appetite-Stimulating Medications in the Inpatient Setting

Howard, M., Hossaini, R., Tolar, C. & Gaviola, M. L., 1 Mar 2019, In : Annals of Pharmacotherapy. 53, 3, p. 261-267 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Megestrol
Appetite
Inpatients
Dronabinol
Meals

Electronic cigarette explosion and burn injuries, US Emergency Departments 2015-2017

Rossheim, M. E., Livingston, M. D., Soule, E. K., Zeraye, H. A. & Thombs, D. L., 1 Jul 2019, In : Tobacco Control. 28, 4, p. 472-474 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Explosions
Hospital Emergency Service
electronics
Wounds and Injuries
surveillance
Health Personnel
Clinical Trials
Drug and Narcotic Control
United States Food and Drug Administration
Patient Safety
2 Citations (Scopus)

Evaluating Personalized Feedback Intervention Framing with a Randomized Controlled Trial to Reduce Young Adult Alcohol-Related Sexual Risk Taking

Lewis, M. A., Rhew, I. C., Fairlie, A. M., Swanson, A., Anderson, J. & Kaysen, D., 15 Apr 2019, In : Prevention Science. 20, 3, p. 310-320 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Risk-Taking
Sexual Behavior
Young Adult
Randomized Controlled Trials
Alcohols

Evaluation of pharmacy-based telephone interventions on medication pick-up rates: a retrospective, quality improvement study at charity outpatient clinics

Tatachar, A. V., Cole, L. C., Nguyen, H. L. & Heinrich, K., 1 Jan 2019, In : International Journal of Pharmacy Practice.

Research output: Contribution to journalArticleResearchpeer-review

Charities
Quality Improvement
Ambulatory Care Facilities
Telephone
Logistics

Examining the Influence of Religious and Spiritual Beliefs on HPV Vaccine Uptake Among College Women

Best, A. L., Thompson, E. L., Adamu, A. M., Logan, R., Delva, J., Thomas, M., Cunningham, E., Vamos, C. & Daley, E., 1 Jan 2019, In : Journal of Religion and Health.

Research output: Contribution to journalArticleResearchpeer-review

Papillomavirus Vaccines
Religion
Vaccination
Sexual Behavior
Spirituality

Exosomes derived from bone mesenchymal stem cells ameliorate early inflammatory responses following traumatic brain injury

Ni, H., Yang, S., Siaw-Debrah, F., Hu, J., Wu, K., He, Z., Yang, J., Pan, S., Lin, X., Ye, H., Xu, Z., Wang, F., Jin, K., Zhuge, Q. & Huang, L., 1 Jan 2019, In : Frontiers in Neuroscience. 13, JAN, 14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Exosomes
Mesenchymal Stromal Cells
Bone and Bones
Microglia
Macrophages

Expanding beyond the current core STR loci: An exploration of 73 STR markers with increased diversity for enhanced DNA mixture deconvolution

Novroski, N. M. M., Wendt, F. R., Woerner, A. E., Bus, M. M., Coble, M. D. & Budowle, B., 1 Jan 2019, In : Forensic Science International: Genetics. 38, p. 121-129 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Microsatellite Repeats
Alleles
DNA
Forensic Genetics
Population Genetics

Exploring the 1000 Genomes Project haplotype reporting for the CYP2D6 pharmacogene

Wendt, F. R., Woerner, A. E., Sajantila, A., Moura-Neto, R. S. & Budowle, B., 1 May 2019, In : International journal of legal medicine. 133, 3, p. 807-810 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Cytochrome P-450 CYP2D6
Haplotypes
Genome

Expression and function of transient receptor potential ankyrin 1 ion channels in the caudal nucleus of the solitary tract

Feng, L., Uteshev-Gaard, V. V. & Premkumar, L. S., 1 May 2019, In : International journal of molecular sciences. 20, 9, 2065.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Ankyrins
Solitary Nucleus
navigation technology satellites
Ion Channels
nuclei
1 Citation (Scopus)

Forensic human identification with targeted microbiome markers using nearest neighbor classification

Woerner, A. E., Novroski, N. M. M., Wendt, F. R., Ambers, A. D., Wiley, R., Schmedes, S. E. & Budowle, B., 1 Jan 2019, In : Forensic Science International: Genetics. 38, p. 130-139 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Forensic Anthropology
Microbiota
Forensic Genetics
Population Genetics
Phylogeny

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Mar 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein

Genistein: mechanisms of action for a pleiotropic neuroprotective agent in stroke

Schreihofer, D. & Oppong-Gyebi, A., 3 Jun 2019, In : Nutritional Neuroscience. 22, 6, p. 375-391 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Genistein
Neuroprotective Agents
Stroke
Estrogens
Brain Injuries

Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease

Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In : Neuroscience. 414, p. 8-27 20 p.

Research output: Contribution to journalArticleResearchpeer-review

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine 3-Monooxygenase
Parkinson Disease
Dopamine
3,4-Dihydroxyphenylacetic Acid

Global research initiatives to understand the prescription drug misuse epidemic and ways to monitor and intervene

Rickles, N. M., Fleming, M. L. & Björnsdottir, I., 1 Aug 2019, In : Research in Social and Administrative Pharmacy. 15, 8, p. 907-909 3 p.

Research output: Contribution to journalEditorialResearch

Prescription Drug Misuse
Prescription Drugs
Research

Glucocorticoid receptor transactivation is required for glucocorticoid-induced ocular hypertension and glaucoma

Patel, G. C., Millar, J. C. & Clark, A., 1 May 2019, In : Investigative Ophthalmology and Visual Science. 60, 6, p. 1967-1978 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Ocular Hypertension
Trabecular Meshwork
Glucocorticoid Receptors
Glaucoma
Transcriptional Activation

Group-based trajectory models to identify sociodemographic and clinical predictors of adherence patterns to statin therapy among older adults

Vadhariya, A., Fleming, M. L., Johnson, M. L., Essien, E. J., Serna, O., Esse, T., Choi, J., Boklage, S. H. & Abughosh, S. M., 1 Jun 2019, In : American Health and Drug Benefits. 12, 4, p. 202-211 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Medicare Part C
Therapeutics
Medication Adherence
Therapy

Head-Eye Coordination of Humanoid Robot with Potential Controller

Wijayasinghe, I. B., Das, S. K., Miller, H. L., Bugnariu, N. & Popa, D. O., 15 Apr 2019, In : Journal of Intelligent and Robotic Systems: Theory and Applications. 94, 1, p. 15-27 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Robots
Controllers
Robotics
Anthropomorphic robots
Eye movements
1 Citation (Scopus)

HEART Score Risk Stratification of Low-Risk Chest Pain Patients in the Emergency Department: A Systematic Review and Meta-Analysis

Laureano-Phillips, J., Robinson, R. D., Aryal, S., Blair, S., Wilson, D., Boyd, K., Schrader, C. D., Zenarosa, N. R. & Wang, H., 1 Aug 2019, In : Annals of Emergency Medicine. 74, 2, p. 187-203 17 p.

Research output: Contribution to journalReview articleResearchpeer-review

Troponin
Age Factors
Chest Pain
Meta-Analysis
Hospital Emergency Service

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Oxidative stress
Young Adult
Oxidative Stress
Hemorrhage

High-risk adolescents’ sexuality education preferences based on Hispanic ethnicity

Maness, S. B., Wilson, K. L., Thompson, E. L., Rosen, B. L. & Zingg, T., 1 Jan 2019, In : Sex Education.

Research output: Contribution to journalArticleResearchpeer-review

adolescent sexuality
ethnicity
adolescent
pregnancy
education

Homozygous rare Parn missense mutation in familial pulmonary fibrosis

Zhang, D., Zhou, Z., Abu-Hijleh, M., Batra, K., Xing, C. & Garcia, C. K., 15 Mar 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 6, p. 797-799 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Pulmonary Fibrosis
Missense Mutation

How Is Health Literacy Related to Pap Testing Among US Women?

Thompson, E. L., Wheldon, C. W., Vamos, C. A., Griner, S. B. & Daley, E. M., 15 Aug 2019, In : Journal of Cancer Education. 34, 4, p. 789-795 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Health Literacy
Uterine Cervical Neoplasms
Papanicolaou Test
Logistic Models
Sexually Transmitted Diseases

Human papillomavirus risk perceptions and relationship status: a barrier to HPV vaccination?

Thompson, E. L., Vamos, C. A., Piepenbrink, R., Kadono, M., Vázquez-Otero, C., Matthes, S. & Daley, E. M., 1 Oct 2019, In : Journal of Behavioral Medicine. 42, 5, p. 991-997 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Vaccination
Young Adult
Logistic Models
Papillomavirus Vaccines
Women's Rights

Human Papillomavirus Vaccination and School Entry Requirements: Politically Challenging, but Not Impossible

Daley, E., Thompson, E. L. & Zimet, G., 1 Jan 2019, In : JAMA Pediatrics. 173, 1, p. 6-7 2 p.

Research output: Contribution to journalComment/debateResearch

Vaccination

Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death

Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., 1 Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Retinal Ganglion Cells
Cell Death
Nerve Crush
Animal Models
Retina

Identification of Binding Sites for Efflux Pump Inhibitors of the AcrAB-TolC Component AcrA

Darzynkiewicz, Z. M., Green, A. T., Abdali, N., Hazel, A., Fulton, R. L., Kimball, J., Gryczynski, Z., Gumbart, J. C., Parks, J. M., Smith, J. C. & Zgurskaya, H. I., 19 Feb 2019, In : Biophysical Journal. 116, 4, p. 648-658 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Binding Sites
Fluorescence Spectrometry
Molecular Dynamics Simulation
Site-Directed Mutagenesis
Gram-Negative Bacteria

Identification of long non-coding RNA-related and -coexpressed mRNA biomarkers for hepatocellular carcinoma

Zhang, F., Ding, L., Cui, L., Barber, R. C. & Deng, B., 31 Jan 2019, In : BMC Medical Genomics. 12, 25.

Research output: Contribution to journalArticleResearchpeer-review

Long Noncoding RNA
Hepatocellular Carcinoma
Biomarkers
Messenger RNA
Neoplasms

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S. L., Sabnis, N., Kong, X., Yang, X., Lopez-Berestein, G., Lacko, A. G. & Sood, A. K., 15 Aug 2019, In : Oncogene. 38, 33, p. 6095-6108 14 p.

Research output: Contribution to journalArticleResearchpeer-review

MicroRNAs
Ovarian Neoplasms
Neoplasms
CD36 Antigens
Vascular Endothelial Growth Factor A