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2006

Complex dependence of substrate stiffness and serum concentration on cell-force generation

Karamichos, D., Brown, R. A. & Mudera, V., 1 Aug 2006, In : Journal of Biomedical Materials Research - Part A. 78, 2, p. 407-415 9 p.

Research output: Contribution to journalArticle

2001

Activation of Phospholipase C-ε by Heterotrimeric G Protein βγ-Subunits

Wing, M. R., Houston, D., Kelley, G. G., Der, C. J., Siderovski, D. P. & Harden, T. K., 21 Dec 2001, In : Journal of Biological Chemistry. 276, 51, p. 48257-48261 5 p.

Research output: Contribution to journalArticle

Open Access
2005

Cellular responses to external mechanical stimuli when seeded to 3D collagen

Karamichos, D., Brown, R. & Mudera, V., 1 Jul 2005, In : European Cells and Materials. 10, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

2009

Anthropological perspectives on the challenges to monitoring and evaluating HIV and AIDS programming in Lesotho

Turkon, D., Himmelgreen, D., Romero-Daza, N. & Noble, C., 1 Dec 2009, In : African Journal of AIDS Research. 8, 4, p. 473-480 8 p.

Research output: Contribution to journalReview article

2007
Open Access
2011

Transforming growth factor-β3 regulates assembly of a non-fibrotic matrix in a 3D corneal model

Karamichos, D., Hutcheon, A. E. K. & Zieske, J. D., 1 Aug 2011, In : Journal of Tissue Engineering and Regenerative Medicine. 5, 8, p. e228-e238

Research output: Contribution to journalArticle

2017

Quercetin and the ocular surface: What we know and where we are going

McKay, T. B. & Karamichos, D., 1 Mar 2017, In : Experimental Biology and Medicine. 242, 6, p. 565-572 8 p.

Research output: Contribution to journalArticle

2019

Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages

Serafin, D. S., Allyn, B., Sassano, M. F., Timoshchenko, R. G., Mattox, D., Brozowski, J. M., Siderovski, D. P., Truong, Y. K., Esserman, D., Tarrant, T. K. & Billard, M. J., Feb 2019, In : Molecular Immunology. 106, p. 12-21 10 p.

Research output: Contribution to journalArticle

2004

Purification and In Vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides

Kimple, R. J., Willard, F. S. & Siderovski, D. P., 1 Jan 2004, Regulators of G-Protein Signaling, Part B. Academic Press Inc., p. 419-436 18 p. (Methods in Enzymology; vol. 390).

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

A New Era for Analytical Cellular Pathology

Karamichos, D., 1 Jan 2020, In : Analytical Cellular Pathology. 2020, 8502160.

Research output: Contribution to journalEditorial

Open Access
2016

The Impact of the Teen Outreach Program on Sexual Intentions and Behaviors

Walsh-Buhi, E. R., Marhefka, S. L., Wang, W., Debate, R., Perrin, K., Singleton, A., Noble, C. A., Rahman, S., Maness, S. B., Mahony, H., Ziemba, R., Malmi, M., Marwah, E., Hall, K., Turner, D. A., Blunt-Vinti, H., Noble, S. M. & Daley, E. M., 1 Sep 2016, In : Journal of Adolescent Health. 59, 3, p. 283-290 8 p.

Research output: Contribution to journalArticle

2004

Analysis of interactions between regulator of G-protein signaling-14 and microtubules

Martin-McCaffrey, L., Willard, F. S., Pajak, A., Dagnino, L., Siderovski, D. P. & D'Souza, S. J. A., 1 Jan 2004, Regulators of G-Protein Signaling, Part B. Academic Press Inc., p. 240-258 19 p. (Methods in Enzymology; vol. 390).

Research output: Chapter in Book/Report/Conference proceedingChapter

2008

A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction

Kimple, A. J., Yasgar, A., Hughes, M., Jadhav, A., Willard, F. S., Muller, R. E., Austin, C. P., Inglese, J., Ibeanu, G. C., Siderovski, D. P. & Simeonov, A., 1 Jun 2008, In : Combinatorial Chemistry and High Throughput Screening. 11, 5, p. 396-409 14 p.

Research output: Contribution to journalReview article

2005

Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN

McCudden, C. R., Willard, F. S., Kimple, R. J., Johnston, C. A., Hains, M. D., Jones, M. B. & Siderovski, D. P., 10 Sep 2005, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1745, 2, p. 254-264 11 p.

Research output: Contribution to journalArticle

Open Access
1995

Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)

Matsuyama, T., Grossman, A., Mittrücker, H. W., Siderovski, D. P., Kiefer, F., Kawakami, T., Richardson, C. D., Taniguchi, T., Yoshinaga, S. K. & Mak, T. W., 25 Jun 1995, In : Nucleic Acids Research. 23, 12, p. 2127-2136 10 p.

Research output: Contribution to journalArticle

2003

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P. & Gönczy, P., 20 Jun 2003, In : Science. 300, 5627, p. 1957-1961 5 p.

Research output: Contribution to journalArticle

2008

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits

Soundararajan, M., Willard, F. S., Kimple, A. J., Turnbull, A. P., Ball, L. J., Schoch, G. A., Gileadi, C., Fedorov, O. Y., Dowler, E. F., Higman, V. A., Hutsell, S. Q., Sundström, M., Doyle, D. A. & Siderovski, D. P., 29 Apr 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 17, p. 6457-6462 6 p.

Research output: Contribution to journalArticle

2010

The superfamily of "regulator of g-protein signaling" (rgs) proteins

Willard, M. D., Willard, F. S. & Siderovski, D. P., 1 Dec 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 2. p. 1683-1703 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma

Priyadarsini, S., McKay, T. B., Sarker-Nag, A., Allegood, J., Chalfant, C., Ma, J. X. & Karamichos, D., 1 Dec 2016, In : Experimental eye research. 153, p. 90-100 11 p.

Research output: Contribution to journalArticle

Establishment of a 3D In vitro model to accelerate the development of human therapies against corneal diabetes

Priyadarsini, S., Sarker-Nag, A., Rowsey, T. G., Ma, J. X. & Karamichos, D., Dec 2016, In : PLoS ONE. 11, 12, e0168845.

Research output: Contribution to journalArticle

Open Access
2006

The R6A-1 peptide binds to switch II of Gαi1 but is not a GDP-dissociation inhibitor

Willard, F. S. & Siderovski, D. P., 27 Jan 2006, In : Biochemical and Biophysical Research Communications. 339, 4, p. 1107-1112 6 p.

Research output: Contribution to journalArticle

2000

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel

Schiff, M. L., Siderovski, D. P., Jordan, J. D., Brothers, G., Snow, B., De Vries, L., Ortiz, D. F. & Diversé-Pierluissi, M., 7 Dec 2000, In : Nature. 408, 6813, p. 723-727 5 p.

Research output: Contribution to journalArticle

2019

Corneal epithelial–stromal fibroblast constructs to study cell–cell communication in vitro

McKay, T. B., Karamichos, D., Zieske, J. D., Hutcheon, A. E. K. & Guo, X., Dec 2019, In : Bioengineering. 6, 4, 110.

Research output: Contribution to journalArticle

Open Access
2011

Altered gene expression profile in vaginal polypoid endometriosis resembles peritoneal endometriosis and is consistent with increased local estrogen production

Syrcle, S. M., Pelch, K. E., Schroder, A. L., Nichols, B. M., Mills, M. P., Barrier, B. F., Havey, A. D. & Nagel, S. C., 1 Mar 2011, In : Gynecologic and Obstetric Investigation. 71, 2, p. 77-86 10 p.

Research output: Contribution to journalArticle

2002

The GoLoco motif: heralding a new tango between G protein signaling and cell division.

Kimple, R. J., Willard, F. S. & Siderovski, D. P., Apr 2002, In : Molecular interventions. 2, 2, p. 88-100 13 p.

Research output: Contribution to journalReview article

2007

Rgs1 regulates multiple Gα subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism

Liu, H., Suresh, A., Willard, F. S., Siderovski, D. P., Lu, S. & Naqvi, N. I., 7 Feb 2007, In : EMBO Journal. 26, 3, p. 690-700 11 p.

Research output: Contribution to journalArticle

2002

Regulators of G-protein signalling as new central nervous system drug targets

Neubig, R. R. & Siderovski, D. P., 1 Mar 2002, In : Nature Reviews Drug Discovery. 1, 3, p. 187-197 11 p.

Research output: Contribution to journalReview article

2004

Guanine nuoleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: Alanine-to-aspartate mutation restores function to an inactive second GoLoco motif

Kimple, R. J., Willard, F. S., Hains, M. D., Jones, M. B., Nweke, G. K. & Siderovski, D. P., 15 Mar 2004, In : Biochemical Journal. 378, 3, p. 801-808 8 p.

Research output: Contribution to journalArticle

2002

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

Lambert, J. M., Lambert, Q. T., Reuther, G. W., Malliri, A., Siderovski, D. P., Sondek, J., Collard, J. G. & Der, C. J., Aug 2002, In : Nature Cell Biology. 4, 8, p. 621-625 5 p.

Research output: Contribution to journalArticle

2017

Differential Effects of Hormones on Cellular Metabolism in Keratoconus in Vitro

McKay, T. B., Hjortdal, J., Sejersen, H. & Karamichos, D., 17 Feb 2017, In : Scientific Reports. 7, 42896.

Research output: Contribution to journalArticle

Open Access
2006

Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization

Paing, M. M., Johnston, C. A., Siderovski, D. P. & Trejo, J. A., 1 Apr 2006, In : Molecular and Cellular Biology. 26, 8, p. 3231-3242 12 p.

Research output: Contribution to journalArticle

Open Access
2018

Exploring the endocrine activity of air pollutants associated with unconventional oil and gas extraction

Bolden, A. L., Schultz, K., Pelch, K. E. & Kwiatkowski, C. F., 21 Mar 2018, In : Environmental Health: A Global Access Science Source. 17, 1, 26.

Research output: Contribution to journalReview article

Open Access
2005

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

Siderovski, D. P. & Willard, F. S., 2005, In : International journal of biological sciences. 1, 2, p. 51-66 16 p.

Research output: Contribution to journalReview article

Open Access
2017

Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

Qi, H., Priyadarsini, S., Nicholas, S. E., Sarker-Nag, A., Allegood, J., Chalfant, C. E., Mandal, N. A. & Karamichos, D., 1 Jan 2017, In : Journal of Lipid Research. 58, 4, p. 636-648 13 p.

Research output: Contribution to journalArticle

Open Access
2009

Two Gαi1 rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activity

Zielinski, T., Kimple, A. J., Hutsell, S. Q., Koeff, M. D., Siderovski, D. P. & Lowery, R. G., 1 Dec 2009, In : Journal of Biomolecular Screening. 14, 10, p. 1195-1206 12 p.

Research output: Contribution to journalArticle

Open Access
1998

Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): Genomic structure and chromosomal localization of the human gene

Snow, B. E., Antonio, L., Suggs, S. & Siderovski, D. P., 12 Jan 1998, In : Gene. 206, 2, p. 247-253 7 p.

Research output: Contribution to journalArticle

1994

Evaluation of a twice-a-week application of 1% niclosamide lotion in preventing Schistosoma haematobium reinfection

Podgore, J. K., Abu-Elyazeed, R. R., Mansour, N. S., Youssef, F. G., Hibbs, R. G. & Gere, J. A., 1 Jan 1994, In : American Journal of Tropical Medicine and Hygiene. 51, 6, p. 875-879 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2000

Integration of aortic nerve inputs in hypertensive rats

Zhang, J. & Mifflin, S. W., Jan 2000, In : Hypertension. 35, 1 II, p. 430-436 7 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
2013

Uncertainties in estimating health risks associated with exposure to ionising radiation.

Preston, R. J., Boice, J. D., Brill, A. B., Chakraborty, R., Conolly, R., Hoffman, F. O., Hornung, R. W., Kocher, D. C., Land, C. E., Shore, R. E. & Woloschak, G. E., Sep 2013, In : Journal of radiological protection : official journal of the Society for Radiological Protection. 33, 3, p. 573-588 16 p.

Research output: Contribution to journalArticle

37 Scopus citations
1993

RAMHA: A PC-based Monte-Carlo simulation of random saturation mutagenesis

Siderovski, D. P. & Mak, T. W., Nov 1993, In : Computers in Biology and Medicine. 23, 6, p. 463-474 12 p.

Research output: Contribution to journalArticle

1996

A new family of regulators of G-protein-coupled receptors?

Siderovski, D. P., Hessel, A., Chung, S., Mak, T. W. & Tyers, M., 1 Jan 1996, In : Current Biology. 6, 2, p. 211-212 2 p.

Research output: Contribution to journalArticle

Open Access
2005

Structure of Gαi1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange

Johnston, C. A., Willard, F. S., Jezyk, M. R., Fredericks, Z., Bodor, E. T., Jones, M. B., Blaesius, R., Watts, V. J., Harden, T. K., Sondek, J., Ramer, J. K. & Siderovski, D. P., 1 Jul 2005, In : Structure. 13, 7, p. 1069-1080 12 p.

Research output: Contribution to journalArticle

Open Access
2006

Minimal determinants for binding activated Gα from the structure of a Gαil-peptide dimer

Johnston, C. A., Lobanova, E. S., Shavkunov, A. S., Low, J., Ramer, J. K., Blaesius, R., Fredericks, Z., Willard, F. S., Kuhlman, B., Arshavsky, V. Y. & Siderovski, D. P., 26 Sep 2006, In : Biochemistry. 45, 38, p. 11390-11400 11 p.

Research output: Contribution to journalArticle

2017

A multi-omics informatics approach for identifying molecular mechanisms and biomarkers in clinical patients with endometriosis

Akter, S., Wilshire, G., Davis, J. W., Bromfield, J., Crowder, S., Joshi, T., Pelch, K., Schust, D. J., Meng, A., Barrier, B. & Nagel, S. C., 15 Dec 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Yoo, I., Zheng, J. H., Gong, Y., Hu, X. T., Shyu, C-R., Bromberg, Y., Gao, J. & Korkin, D. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 2221-2223 3 p. (Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017; vol. 2017-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2000

World population data for the HLA-DQA1, PM® and D1S80 loci with least and most common profile frequencies for combinations of loci estimated following NRC II guidelines

Peterson, B. L., Su, B., Chakraborty, R., Budowle, B. & Gaensslen, R. E., Jan 2000, In : Journal of Forensic Sciences. 45, 1, p. 118-146 29 p.

Research output: Contribution to journalArticle

11 Scopus citations
2008

Increasing percent burn is correlated with increasing inflammation in an adult rodent model

Barber, R. C., Maass, D. L., White, D. J. & Horton, J. W., 1 Oct 2008, In : Shock. 30, 4, p. 388-393 6 p.

Research output: Contribution to journalArticle

24 Scopus citations
2003

Methodologic quality and genotyping reproducibility in studies of tumor necrosis factor -308 G→A single nucleotide polymorphism and bacterial sepsis: Implications for studies of complex traits

Peters, D. L., Barber, R. C., Flood, E. M., Garner, H. R. & O'Keefe, G. E., 1 Jun 2003, In : Critical Care Medicine. 31, 6, p. 1691-1696 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2006

Detecting genetic predisposition for complicated clinical outcomes after burn injury

Barber, R. C., Chang, L. Y., Purdue, G. F., Hunt, J. L., Arnoldo, B. D., Aragaki, C. C. & Horton, J. W., 1 Nov 2006, In : Burns. 32, 7, p. 821-827 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2008

Exhaustive prediction of disease susceptibility to coding base changes in the human genome

Kulkarni, V., Errami, M., Barber, R. & Garner, H. R., 12 Aug 2008, In : BMC Bioinformatics. 9, SUPPL. 9, S3.

Research output: Contribution to journalArticle

11 Scopus citations
2011
93 Scopus citations