Find Research Outputs

2019

Impact of environmental stressors on tolerance to hemorrhage in humans

Crandall, C. G., Rickards, C. A. & Johnson, B. D., Feb 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 2, p. R88-R100

Research output: Contribution to journalReview article

Lower Body Negative Pressure
Hemorrhage
Altitude Sickness
Hypovolemia
Military Personnel
4 Citations (Scopus)

Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework

Wu, R. R., Myers, R. A., Sperber, N., Voils, C. I., Neuner, J., McCarty, C. A., Haller, I. V., Harry, M., Fulda, K. G., Cross, D. S., Dimmock, D., Rakhra-Burris, T., Buchanan, A. H., Ginsburg, G. S. & Orlando, L. A., 1 Feb 2019, In : Genetics in Medicine. 21, 2, p. 331-338 8 p.

Research output: Contribution to journalArticle

Medical History Taking
Primary Health Care
Family Health
Clinical Decision Support Systems
Delivery of Health Care

Improvement in mental health following total hip arthroplasty: The role of pain and function

Nguyen, U. S. D. T., Perneger, T., Franklin, P. D., Barea, C., Hoffmeyer, P. & Lübbeke, A., 29 Jun 2019, In : BMC Musculoskeletal Disorders. 20, 1, 307.

Research output: Contribution to journalArticle

Open Access
Arthroplasty
Hip
Mental Health
Pain
Ontario

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., 1 Jan 2019, (Accepted/In press) In : Progress in Retinal and Eye Research. 100799.

Research output: Contribution to journalArticle

Glaucoma
Rodentia
Pressure
Intraocular Pressure
Low Tension Glaucoma

Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats

Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., Jul 2019, In : Neurochemistry International. 127, p. 64-72 9 p.

Research output: Contribution to journalArticle

Autophagy
Stroke
Middle Cerebral Artery Infarction
Young Adult
Up-Regulation

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Olivencia-Yurvati, A. H., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journalArticle

Open Access
Ventriculoperitoneal Shunt
Cerebrospinal Fluid
Swine
Hydrocephalus
Cerebrospinal fluid

Intracranial atherosclerotic disease

Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., 1 Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.

Research output: Contribution to journalArticle

Intracranial Arteriosclerosis
Stroke
Therapeutics
Recurrence
Risk Management
1 Citation (Scopus)

In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection

Weiss, W., Pulse, M. E., Nguyen, P. & Growcott, E. J., 1 Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e02214-18.

Research output: Contribution to journalArticle

Klebsiella Infections
Monobactams
Carbapenems
Klebsiella pneumoniae
Uranyl Nitrate
Cell membranes
Brain
Coloring Agents
Dyes
Nanoparticles
4 Citations (Scopus)

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Exercise
Clinical Trials
Hypoxia-Inducible Factor 1
Microglia

Knee Loading After ACL-R Is Related to Quadriceps Strength and Knee Extension Differences Across the Continuum of Care

Garrison, J. C., Hannon, J., Goto, S., Kosmopoulos, V., Aryal, S., Bush, C., Bothwell, J. M. & Singleton, S. B., 1 Jan 2019, In : Orthopaedic Journal of Sports Medicine. 7, 10

Research output: Contribution to journalArticle

Open Access
Continuity of Patient Care
Anterior Cruciate Ligament
Knee
Extremities
Anterior Cruciate Ligament Reconstruction

Large pelvic tubercle in orangutans relates to the adductor longus muscle

Shearer, B. M., Muchlinski, M. & Hammond, A. S., 1 Jan 2019, In : PeerJ. 2019, 8, e7273.

Research output: Contribution to journalArticle

Open Access
Pongo
Pongo pygmaeus
Muscle
Muscles
muscles

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D 3 Receptor (D 3 R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)

Reilly, S. W., Riad, A. A., Hsieh, C. J., Sahlholm, K., Jacome, D. A., Griffin, S., Taylor, M., Weng, C. C., Xu, K., Kirschner, N., Luedtke, R. T., Parry, C., Malhotra, S., Karanicolas, J. & Mach, R. H., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5132-5147 16 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Dopamine
Ligands
Adrenergic Agents
Pharmaceutical Preparations
1 Citation (Scopus)

Limited Intragenerational Mobility of Surgical Caseload of Iowa Hospitals

O'Neill, L., Dexter, F. & Epstein, R. H., 1 Jul 2019, In : Journal of Medical Systems. 43, 7, 187.

Research output: Contribution to journalArticle

Least-Squares Analysis
Economics
Statistics
Growth

Linkage, recombination, and mutation rate analyses of 19 X-chromosomal STR loci in Chinese Southern Han pedigrees

Yang, X., Chen, Y., Zeng, X., Chen, L., Liu, C., Liu, H., Xu, Q., Budowle, B. & Liu, C., 1 Nov 2019, In : International journal of legal medicine. 133, 6, p. 1691-1698 8 p.

Research output: Contribution to journalArticle

Linkage Disequilibrium
Mutation Rate
Pedigree
Genetic Recombination
Haplotypes
Locomotion
N-Methyl-3,4-methylenedioxyamphetamine
Rats
Methamphetamine
Cocaine
1 Citation (Scopus)
Microsatellite Repeats
Technology
Alleles
Rubiaceae
Tandem Repeat Sequences

Metformin alters locomotor and cognitive function and brain metabolism in normoglycemic mice

Li, W., Chaudhari, K., Shetty, R., Winters, A., Gao, X., Hu, Z., Ge, W. P., Sumien, N., Forster, M., Liu, R. & Yang, S. H., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 949-963 15 p.

Research output: Contribution to journalArticle

Open Access
Metformin
Cognition
Brain
Energy Metabolism
Glycerolphosphate Dehydrogenase

Minority Physician Assistant Faculty: A Phenomenological Assessment of Factors Leading to Retention in the Faculty Role

LeLacheur, S. F., Bester, V., Oxendine, L. H., Guidry, C. B., Ryujin, D., Samuels, K. L., Maldonado, A., Bowen, D. & Himmerick, K., 1 Jun 2019, In : The journal of physician assistant education : the official journal of the Physician Assistant Education Association. 30, 2, p. 79-85 7 p.

Research output: Contribution to journalArticle

Physician Assistants
assistant
physician
minority
Mentors

Mitochondrial DNA control region variation in Lebanon, Jordan, and Bahrain

Zimmermann, B., Sturk-Andreaggi, K., Huber, N., Xavier, C., Saunier, J., Tahir, M., Chouery, E., Jalkh, N., Megarbane, A., Bodner, M., Coble, M., Irwin, J., Parsons, T. & Parson, W., Sep 2019, In : Forensic Science International: Genetics. 42, p. 99-102 4 p.

Research output: Contribution to journalArticle

Bahrain
Lebanon
Jordan
Mitochondrial DNA
Population

Models of poststroke depression and assessments of core depressive symptoms in rodents: How to choose?

Tao, X., Yang, W., Zhu, S., Que, R., Liu, C., Fan, T., Wang, J., Mo, D., Zhang, Z., Tan, J., Jin, K., Yenarih, M. A., Song, T. & Wang, Q., Dec 2019, In : Experimental Neurology. 322, 113060.

Research output: Contribution to journalReview article

Rodentia
Stroke
Depression
Animal Models
Anhedonia

Multivariate group-level analysis for task fMRI data with canonical correlation analysis

Zhuang, X., Yang, Z., Sreenivasan, K. R., Mishra, V. R., Curran, T., Nandy, R. R. & Cordes, D., 1 Jul 2019, In : NeuroImage. 194, p. 25-41 17 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Temporal Lobe
Episodic Memory
ROC Curve
Noise

Multivariate higher-order IRT model and MCMC algorithm for linking individual participant data from multiple studies

Mun, E. Y., Huo, Y., White, H. R., Suzuki, S. & de la Torre, J., 1 Jan 2019, In : Frontiers in Psychology. 10, JUN, 328.

Research output: Contribution to journalArticle

Open Access
Markov Chains
Feasibility Studies
Research
Meta-Analysis
Psychology

NADPH oxidase mediates membrane androgen receptor-induced neurodegeneration

Tenkorang, M. A. A., Duong, P. & Cunningham, R. L., 1 Jan 2019, In : Endocrinology. 160, 4, p. 947-963 17 p.

Research output: Contribution to journalArticle

Androgen Receptors
NAD
Oxidoreductases
Oxidative Stress
Phosphates
1 Citation (Scopus)

Nanopore sequencing: An enrichment-free alternative to mitochondrial DNA sequencing

Zascavage, R. R., Thorson, K. & Planz, J. V., 1 Jan 2019, In : Electrophoresis. 40, 2, p. 272-280 9 p.

Research output: Contribution to journalArticle

Nanopores
Mitochondrial DNA
DNA Sequence Analysis
Libraries
DNA
4 Citations (Scopus)

National Trends in Human Papillomavirus Awareness and Knowledge of Human Papillomavirus–Related Cancers

Wheldon, C. W., Krakow, M., Thompson, E. L. & Moser, R. P., 1 Apr 2019, In : American Journal of Preventive Medicine. 56, 4, p. e117-e123

Research output: Contribution to journalArticle

Neoplasms
Uterine Cervical Neoplasms
Penile Neoplasms
Anus Neoplasms
Vaccines

Non-fluorescent filters for fluorescence detection with in-line geometry

Kimball, J., Chavez, J., Ceresa, L., Shah, S., Gryczynski, I. & Gryczynski, Z., 16 May 2019, In : Methods and Applications in Fluorescence. 7, 3, 037001.

Research output: Contribution to journalArticle

Potassium Dichromate
lines (geometry)
chromates
Potassium
Fluorescence

Non-medical strategies to improve pregnancy outcomes of women with gestational diabetes mellitus a literature review

Al Hashmi, I., Nandy, K. & Seshan, V., Feb 2019, In : Sultan Qaboos University Medical Journal. 19, 1, p. e4-e10

Research output: Contribution to journalReview article

Open Access
Gestational Diabetes
Pregnancy Outcome
Mothers
Blood Glucose Self-Monitoring
National Library of Medicine (U.S.)
1 Citation (Scopus)

Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

Das, P., Panda, S. K., Agarwal, B., Behera, S., Ali, S. M., Pulse, M. E., Solomkin, J. S., Opal, S. M., Bhandari, V. & Acharya, S., 1 Dec 2019, In : Scientific Reports. 9, 1, 2904.

Research output: Contribution to journalArticle

Open Access
Punctures
Ligation
Sepsis
Cytokines
Interleukin-10

Novel Investigation of the Deep Band of the Lateral Plantar Aponeurosis and Its Relationship With the Lateral Plantar Nerve

Beck, C. M., Dickerson, A. R., Kadado, K. J., Cohen, Z. A., Blair, S. E., Motley, T. A., Holcomb, J. C. & Fisher, C. L., 1 Nov 2019, In : Foot and Ankle International. 40, 11, p. 1325-1330 6 p.

Research output: Contribution to journalArticle

Foot
Metatarsal Bones
Diving
Aponeurosis

Obstetrics and Gynecology and Family Medicine Residents' Training and Knowledge on Emergency Contraception

Rapkin, R. B., Griner, S. B., Godcharles, C. L., Vamos, C. A., Neelamegam, M., Thompson, E. L. & Daley, E. M., 1 Jun 2019, In : Journal of Women's Health. 28, 6, p. 794-801 8 p.

Research output: Contribution to journalArticle

Postcoital Contraception
Gynecology
Obstetrics
Medicine
Internship and Residency

Origin and bioactivities of thiosulfinated FK228

Liu, X., Currens, G. C., Xue, L. & Cheng, Y., 1 Jan 2019, In : MedChemComm. 10, 4, p. 538-542 5 p.

Research output: Contribution to journalArticle

Bioactivity
Silica Gel
Burkholderia
Histone Deacetylases
romidepsin

Ovarian cancer: Current status and strategies for improving therapeutic outcomes

Chandra, A., Pius, C., Nabeel, M., Nair, M., Vishwanatha, J. K., Ahmad, S. & Basha, R., 1 Nov 2019, In : Cancer Medicine. 8, 16, p. 7018-7031 14 p.

Research output: Contribution to journalReview article

Open Access
Ovarian Neoplasms
Platinum
Drug Therapy
Therapeutics
Survival Rate

Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment

Guenter, R., Aweda, T., Carmona Matos, D. M., Jang, S., Whitt, J., Cheng, Y. Q., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., 1 Jan 2019, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Histone Deacetylase Inhibitors
Neuroendocrine Cells
Therapeutics
Tumor Cell Line

PaCIR: A tool to enhance pharmacist patient care intervention reporting

Clay, P. G., Burns, A. L., Isetts, B. J., Hirsch, J. D., Kliethermes, M. A. & Planas, L. G., 1 Sep 2019, In : Journal of the American Pharmacists Association. 59, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

Open Access
Pharmacists
Patient Care
Checklist
Teleconferencing
Language

Pancreatic cancer: An emphasis on current perspectives in immunotherapy

Patel, K., Siraj, S., Smith, C., Nair, M., Vishwanatha, J. K. & Basha, R., 1 Jan 2019, In : Critical Reviews in Oncogenesis. 24, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Immunotherapy
Neoplasms
Clinical Trials
Programmed Cell Death 1 Receptor
1 Citation (Scopus)

Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

McCarthy, C. G., Goulopoulou, S. & Webb, R. C., 1 Mar 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

Research output: Contribution to journalArticle

Blood Vessels
Hypertension
Inflammation
1 Citation (Scopus)

Personalized normative feedback for heavy drinking: An application of deviance regulation theory

Neighbors, C., DiBello, A. M., Young, C. M., Steers, M. L. N., Rinker, D. V., Rodriguez, L. M., Ryamond Knee, C., Blanton, H. & Lewis, M. A., Apr 2019, In : Behaviour Research and Therapy. 115, p. 73-82 10 p.

Research output: Contribution to journalArticle

Drinking Behavior
Drinking
Health Behavior
Alcohol Drinking
Randomized Controlled Trials
8 Citations (Scopus)

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

International Society to Advance Alzheimer's Research and Treatment, Alzheimer's Association, Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 292-312 21 p.

Research output: Contribution to journalShort survey

Dementia
Alzheimer Disease
Research
Population

Pharmacist-Led Chronic Care Management Services

Yuet, W. C., Gardea, J., Ebert, D. & Martin, R. D., 1 Sep 2019, In : Annals of family medicine. 17, 5, 1 p.

Research output: Contribution to journalArticle

Open Access
Pharmacists
1 Citation (Scopus)

Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection

Pulse, M. E., Weiss, W. J., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e01904-18.

Research output: Contribution to journalArticle

Bacteriocins
Clostridium difficile
Toxicology
Pharmacology
Mesocricetus

Pharmacy educator evaluation of web-based learning

Isaacs, A. N., Walton, A. M., Gonzalvo, J. D., Howard, M. L. & Nisly, S. A., 1 Dec 2019, In : Clinical Teacher. 16, 6, p. 630-635 6 p.

Research output: Contribution to journalArticle

Learning
Pharmacy Education
Students
Education
Pharmacy Schools

Photophysical properties and detection of Valrubicin on plasmonic platforms

Synak, A., Szczepańska, E., Grobelna, B., Gondek, J., Mońka, M., Gryczynski, I. & Bojarski, P., 1 Apr 2019, In : Dyes and Pigments. 163, p. 623-627 5 p.

Research output: Contribution to journalArticle

valrubicin
Silver
Nanoparticles
Plasmons
Gold
5 Citations (Scopus)

Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), 1 Jun 2019, In : Alzheimer's and Dementia. 15, 6, p. 764-775 12 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Clinical Trials
Apolipoprotein E4
Validation Studies

Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

Rafii, M. S., Donohue, M. C., Matthews, D. C., Muranevici, G., Ness, S., O'Bryant, S. & Rissman, R. A., 1 Jan 2019, In : Journal of Alzheimer's Disease. 70, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Down Syndrome
Alzheimer Disease
Biomarkers
Light

Plasmonically-powered hot carrier induced modulation of light emission in a two-dimensional GaAs semiconductor quantum well

Ashalley, E., Gryczynski, K., Wang, Z., Salamo, G. & Neogi, A., 7 Mar 2019, In : Nanoscale. 11, 9, p. 3827-3836 10 p.

Research output: Contribution to journalArticle

Open Access
Hot carriers
Light emission
Semiconductor quantum wells
Modulation
Metal nanoparticles

Population Pharmacokinetics of Pemetrexed in Adult Non–Small Cell Lung Cancer in Indian Patients

Srinivasan, M., Chaturvedula, A., Fossler, M. J., Patil, A., Gota, V. & Prabhash, K., 1 Jan 2019, In : Journal of Clinical Pharmacology. 59, 9, p. 1216-1224 9 p.

Research output: Contribution to journalArticle

Pemetrexed
Non-Small Cell Lung Carcinoma
Pharmacokinetics
Population
Markov Chains

Population pharmacokinetics of primaquine and the effect of hepatic and renal dysfunction: An exploratory approach

Sridharan, K., Sannala, C. K. R., Mallayasamy, S., Chaturvedula, A., Kadam, P., Hase, N., Shukla, A., Gogtay, N. & Thatte, U., 1 Jan 2019, In : Indian Journal of Pharmacology. 51, 1, p. 17-24 8 p.

Research output: Contribution to journalArticle

Primaquine
Pharmacokinetics
Kidney
Liver
Population

Potential two-step proteomic signature for Parkinson's disease: Pilot analysis in the Harvard Biomarkers Study

O'Bryant, S., Edwards, M., Zhang, F., Johnson, L. A., Hall, J., Kuras, Y. & Scherzer, C. R., 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 374-382 9 p.

Research output: Contribution to journalArticle

Open Access
Neurodegenerative Diseases
Proteomics
Parkinson Disease
Biomarkers
Alzheimer Disease
4 Citations (Scopus)

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

for Alzheimer’s Disease Neuroimaging Initiative, 1 Dec 2019, In : Scientific Reports. 9, 1, 1952.

Research output: Contribution to journalArticle

Open Access
Disease Progression
Alzheimer Disease
Learning
Neuroimaging
Area Under Curve