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2019
1 Citation (Scopus)

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival
2 Citations (Scopus)

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Copper
Neoplasms
Powders
tolfenamic acid
Cell Line

Primary care clinics can be a source of exposure to virulent Clostridium (now Clostridioides) difficile: An environmental screening study of hospitals and clinics in Dallas-Fort Worth region

Simecka, J. W., Fulda, K. G., Pulse, M., Lee, J. H., Vitucci, J., Nguyen, P., Taylor, P., Filipetto, F., Espinoza, A. M. & Sharma, S., 1 Jan 2019, In : PLoS ONE. 14, 8, e0220646.

Research output: Contribution to journalArticle

Open Access
Clostridium
Primary Health Care
Screening
Contamination
Pathogens
2018
7 Citations (Scopus)

Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis

Weiss, W. J., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J. W., Valtierra, D., Sabet, M. & Griffith, D. C., Jan 2018, In : Antimicrobial agents and chemotherapy. 62, 1, e01439.

Research output: Contribution to journalArticle

meropenem
Carbapenems
Pyelonephritis
Enterobacteriaceae
Klebsiella pneumoniae
3 Citations (Scopus)

Interleukin-17A exacerbates disease severity in BALB/c mice susceptible to lung infection with Mycoplasma pulmonis

Mize, M. T., Sun, X. L. & Simecka, J. W., 1 Sep 2018, In : Infection and Immunity. 86, 9, e00292-18.

Research output: Contribution to journalArticle

Mycoplasma pulmonis
Interleukin-17
Lung
Mycoplasma Infections
Infection
2016
13 Citations (Scopus)

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation

Sankpal, U. T., Ingersoll, S. B., Ahmad, S., Holloway, R. W., Bhat, V. B., Simecka, J. W., Daniel, L., Kariali, E., Vishwanatha, J. K. & Basha, R., 1 Oct 2016, In : Tumor Biology. 37, 10, p. 14259-14269 11 p.

Research output: Contribution to journalArticle

Cisplatin
Cell Proliferation
Proteins
Proteomics
Reactive Oxygen Species
31 Citations (Scopus)

Combination of Tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

Sankpal, U. T., Nagaraju, G. P., Gottipolu, S. R., Hurtado, M., Jordan, C. G., Simecka, J. W., Shoji, M., El-Rayes, B. & Basha, R., 1 Jan 2016, In : Oncotarget. 7, 3, p. 3186-3200 15 p.

Research output: Contribution to journalArticle

Curcumin
Colonic Neoplasms
Reactive Oxygen Species
Transcription Factors
Growth
9 Citations (Scopus)

Regulatory CD4+ CD25+ T cells dampen inflammatory disease in murine mycoplasma pneumonia and promote IL-17 and IFN-γ Responses

Odeh, A. N. & Simecka, J. W., May 2016, In : PLoS ONE. 11, 5, e0155648.

Research output: Contribution to journalArticle

Mycoplasma pneumoniae
Mycoplasma Pneumonia
T-cells
Interleukin-17
Mycoplasma
17 Citations (Scopus)
Spices
Curcumin
NF-kappa B
Pancreatic Neoplasms
Cell Cycle
10 Citations (Scopus)

Thiopurine prodrugs mediate immunosuppressive effects by interfering with Rac1 protein function

Shin, J. Y., Wey, M., Umutesi, H. G., Sun, X., Simecka, J. & Heo, J., 24 Jun 2016, In : Journal of Biological Chemistry. 291, 26, p. 13699-13714 16 p.

Research output: Contribution to journalArticle

rac1 GTP-Binding Protein
Prodrugs
6-Mercaptopurine
Immunosuppressive Agents
T-cells