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  • Laszlo Prokai
2019

[ 99 mTc-HYNIC-N-dodecylamide]:a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging

Isaac-Olivé, K., Ocampo-García, B. E., Aranda-Lara, L., Santos-Cuevas, C. L., Jiménez-Mancilla, N. P., Luna-Gutiérrez, M. A., Medina, L. A., Nagarajan, B., Sabnis, N., Raut, S., Prokai, L. & Lacko, A. G., 14 Jan 2019, In : Nanoscale. 11, 2, p. 541-551 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

A novel prodrug approach for central nervous system-selective estrogen therapy

Prokai-Tatrai, K. & Prokai, L., 19 Nov 2019, In : Molecules. 24, 22, 4197.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach

Prokai-Tatrai, K., De La Cruz, D. L., Nguyen, V., Ross, B. P., Toth, I. & Prokai, L., Jul 2019, In : Pharmaceutics. 11, 7, 349.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

d’Oliveira, G. D. C., Custodio, J. M. F., Moura, A. F., Napolitano, H. B., Pérez, C. N., Moraes, M. O., Prókai, L. & Perjési, P., 1 Sep 2019, In : Medicinal Chemistry Research. 28, 9, p. 1448-1460 13 p.

Research output: Contribution to journalArticle

Open Access
2018
1 Scopus citations

An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease

Tschiffely, A. E., Schuh, R. A., Prokai-Tatrai, K., Ottinger, M. A. & Prokai, L., Feb 2018, In : Hormones and Behavior. 98, p. 16-21 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Risk-associated and pathway-based method to detect association with Alzheimer's disease

Mitchel, J., Prokai, L., Deng, Y., Zhang, F. & Barber, R., 1 Jan 2018, In : International Journal of Computational Biology and Drug Design. 11, 1-2

Research output: Contribution to journalEditorial

2017

Effect of short-term DHEA supplementation on serum and hippocampal estrogen concentrations in perimenopausal female rhesus macaques

Urbanski, H. F., Sorwell, K. G., Prokai, L. & Kohama, S. G., Jul 2017, In : Neurobiology of Aging. 55, p. 172-174 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mannich Ketones as Possible Antimycobacterial Agents

Lutz, Z., Orbán, K., Bóna, Á., Márk, L., Maász, G., Prókai, L., Seress, L. & Lóránd, T., Sep 2017, In : Archiv der Pharmazie. 350, 9, 1700102.

Research output: Contribution to journalArticle

1 Scopus citations

Targeting alpha toxin to mitigate its lethal toxicity in ferret and rabbit models of Staphylococcus aureus necrotizing pneumonia

Diep, B. A., Hilliard, J. J., Le, V. T. M., Tkaczyk, C., Le, H. N., Tran, V. G., Rao, R. L., Dip, E. C., Pereira-Franchi, E. P., Cha, P., Jacobson, S., Broome, R., Cheng, L. I., Weiss, W., Prokai, L., Nguyen, V., Stover, C. K. & Sellman, B. R., Apr 2017, In : Antimicrobial agents and chemotherapy. 61, 4, 02456-16.

Research output: Contribution to journalArticle

16 Scopus citations
2016

A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease

Tschiffely, A. E., Schuh, R. A., Prokai-Tatrai, K., Prokai, L. & Ottinger, M. A., 1 Jul 2016, In : Hormones and Behavior. 83, p. 39-44 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cholinergic neurons in the basal forebrain promote wakefulness by actions on neighboring non-cholinergic neurons: An opto-dialysis study

Zant, J. C., Kim, T., Prokai, L., Szarka, S., McNally, J., McKenna, J. T., Shukla, C., Yang, C., Kalinchuk, A. V., McCarley, R. W., Brown, R. E. & Basheer, R., 10 Feb 2016, In : Journal of Neuroscience. 36, 6, p. 2057-2067 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Critical role of alpha-toxin and protective effects of its neutralization by a human antibody in acute bacterial skin and skin structure infections

Le, V. T. M., Tkaczyk, C., Chau, S., Rao, R. L., Dip, E. C., Pereira-Franchi, E. P., Cheng, L., Lee, S., Koelkebeck, H., Hilliard, J. J., Yu, X. Q., Datta, V., Nguyen, V., Weiss, W., Prokai, L., O'Day, T., Stover, C. K., Sellman, B. R. & Diep, B. A., 1 Oct 2016, In : Antimicrobial agents and chemotherapy. 60, 10, p. 5640-5648 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2 Scopus citations

Mass spectrometric analysis of carisoprodol and meprobamate in rat brain microdialysates

Prokai, L., Fryčák, P., Nguyen, V. & Forster, M. J., 1 Oct 2016, In : Journal of Mass Spectrometry. 51, 10, p. 900-907 8 p.

Research output: Contribution to journalArticle

Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery

Merchenthaler, I., Lane, M., Sabnis, G., Brodie, A., Nguyen, V., Prokai, L. & Prokai-Tatrai, K., 1 Aug 2016, In : Scientific Reports. 6, 30721.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a staphylococcus aureus dermonecrosis model

Hilliard, J. J., Datta, V., Tkaczyk, C., Hamilton, M., Sadowska, A., Jones-Nelson, O., O'Day, T., Weiss, W. J., Szarka, S., Nguyen, V., Prokai, L., Suzich, J. A., Stover, C. K. & Sellmana, B. R., 1 Jan 2015, In : Antimicrobial agents and chemotherapy. 59, 1, p. 299-308 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

A survey of the impact of deyolking on biological processes covered by shotgun proteomic analyses of zebrafish embryos

Rahlouni, F., Szarka, S., Shulaev, V. & Prokai, L., 1 Dec 2015, In : Zebrafish. 12, 6, p. 398-407 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
4 Scopus citations

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders

Prokai, L., Nguyen, V., Szarka, S., Garg, P., Sabnis, G., Bimonte-Nelson, H. A., McLaughlin, K. J., Talboom, J. S., Conrad, C. D., Shughrue, P. J., Gould, T. D., Brodie, A., Merchenthaler, I., Koulen, P. & Prokai-Tatrai, K., 22 Jul 2015, In : Science Translational Medicine. 7, 297, 297ra113.

Research output: Contribution to journalArticle

20 Scopus citations