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2019
Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands
Chen, P. J., Taylor, M., Griffin, S. A., Amani, A., Hayatshahi, H., Korzekwa, K., Ye, M., Mach, R. H., Liu, J., Luedtke, R. R., Gordon, J. C. & Blass, B. E., 15 Sep 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2690-2694 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D3 Receptor (D3R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)
Reilly, S. W., Riad, A. A., Hsieh, C. J., Sahlholm, K., Jacome, D. A., Griffin, S., Taylor, M., Weng, C. C., Xu, K., Kirschner, N., Luedtke, R. R., Parry, C., Malhotra, S., Karanicolas, J. & Mach, R. H., 23 May 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5132-5147 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Retraction notice to “Dopamine Ds3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors” [Pharmacology, Biochemistry and Behavior 171 (2018) 46–53](S0091305718300236)(10.1016/j.pbb.2018.05.015)
Powell, G. L., Bonadonna, J. P., Vannan, A., Xu, K., Mach, R. H., Luedtke, R. T. & Neisewander, J. L., 1 Jan 2019, In: Pharmacology Biochemistry and Behavior. 176, 1 p.Research output: Contribution to journal › Comment/debate
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2018
Analogues of Arylamide Phenylpiperazine Ligands to Investigate the Factors Influencing D3 Dopamine Receptor Bitropic Binding and Receptor Subtype Selectivity
Hayatshahi, H. S., Xu, K., Griffin, S. A., Taylor, M., Mach, R. H., Liu, J. & Luedtke, R. R., 19 Dec 2018, In: ACS Chemical Neuroscience. 9, 12, p. 2972-2983 12 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Challenges in the development of dopamine D2- and D3-selective radiotracers for PET imaging studies
Mach, R. H. & Luedtke, R. T., 1 Mar 2018, In: Journal of Labelled Compounds and Radiopharmaceuticals. 61, 3, p. 291-298 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention
Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R., Forster, M. J., Sumien, N. & Ingram, D. K., 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors
Powell, G. L., Bonadonna, J. P., Vannan, A., Xu, K., Mach, R. H., Luedtke, R. R. & Neisewander, J. L., Aug 2018, In: Pharmacology Biochemistry and Behavior. 171, p. 46-53 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors
Powell, G. L., Bonadonna, J. P., Vannan, A., Xu, K., Mach, R. H., Luedtke, R. R. & Neisewander, J. L., Dec 2018, In: Pharmacology Biochemistry and Behavior. 175, p. 123-129 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2017
Dysregulated corticostriatal activity in open-field behavior and the head-twitch response induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine
Rangel-Barajas, C., Estrada-Sánchez, A. M., Barton, S. J., Luedtke, R. R. & Rebec, G. V., 1 Feb 2017, In: Neuropharmacology. 113, p. 502-510 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Highly Selective Dopamine D3 Receptor Antagonists with Arylated Diazaspiro Alkane Cores
Reilly, S. W., Griffin, S., Taylor, M., Sahlholm, K., Weng, C. C., Xu, K., Jacome, D. A., Luedtke, R. R. & Mach, R. H., 14 Dec 2017, In: Journal of Medicinal Chemistry. 60, 23, p. 9905-9910 6 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2016
The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice
Malik, M., Rangel-Barajas, C., Mach, R. H. & Luedtke, R. R., 1 Sep 2016, In: Pharmacology Biochemistry and Behavior. 148, p. 136-144 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2015
Bitropic D3 dopamine receptor selective compounds as potential antipsychotics
Luedtke, R. R., Rangel-Barajas, C., Malik, M., Reichert, D. E. & Mach, R. H., 1 Sep 2015, In: Current Pharmaceutical Design. 21, 26, p. 3700-3724 25 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Pharmacological modulation of abnormal involuntary DOI-induced head twitch response movements in male DBA/2J mice: II. Effects of D3 dopamine receptor selective compounds
Rangel-Barajas, C., Malik, M., Mach, R. H. & Luedtke, R. R., Jun 2015, In: Neuropharmacology. 93, p. 179-190 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands
Peng, X., Wang, Q., Mishra, Y., Xu, J., Reichert, D. E., Malik, M., Taylor, M., Luedtke, R. R. & Mach, R. H., 1 Feb 2015, In: Bioorganic and Medicinal Chemistry Letters. 25, 3, p. 519-523 5 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice
Malik, M., Rangel-Barajas, C., Sumien, N., Su, C., Singh, M., Chen, Z., Huang, R. Q., Meunier, J., Maurice, T., Mach, R. H. & Luedtke, R. R., 1 May 2015, In: British Journal of Pharmacology. 172, 10, p. 2519-2531 13 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations