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2019

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Oxidative stress
Young Adult
Oxidative Stress
Hemorrhage

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Yurvati, A., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., 1 May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Ventriculoperitoneal Shunt
Cerebrospinal Fluid
Swine
Hydrocephalus
Cerebrospinal fluid

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental Physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Ischemic Preconditioning
Exercise
Clinical Trials
Hypoxia-Inducible Factor 1
Microglia
2018
3 Citations (Scopus)

An in vitro oxygen–glucose deprivation model for studying ischemia–reperfusion injury of neuronal cells

Ryou, M. G. & Mallet, R. T., 1 Jan 2018, Methods in Molecular Biology. Humana Press Inc., p. 229-235 7 p. (Methods in Molecular Biology; vol. 1717).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Wounds and Injuries
Oxygen
Cytoprotection
Heart Arrest
Reperfusion Injury
6 Citations (Scopus)

Cardioprotection by intermittent hypoxia conditioning: Evidence, mechanisms, and therapeutic potential

Mallet, R. T., Manukhina, E. B., Ruelas, S. S., Caffrey, J. L. & Downey, H. F., 1 Aug 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 2, p. H216-H232

Research output: Contribution to journalReview articleResearchpeer-review

Ischemia
Myocardial Reperfusion
Coronary Occlusion
Sleep Apnea Syndromes
Tachycardia
4 Citations (Scopus)

Intermittent hypoxia training: Powerful, non-invasive cerebroprotection against ethanol withdrawal excitotoxicity

Jung, E. & Mallet, R. T., 1 Oct 2018, In : Respiratory Physiology and Neurobiology. 256, p. 67-78 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

Ethanol
Amyloid
Glutamic Acid
Oxidative Stress
Adenosine Triphosphate
1 Citation (Scopus)

Pyruvate enhancement of cardiac performance: Cellular mechanisms and clinical application

Mallet, R. T., Yurvati, A. & Bünger, R., 1 Jan 2018, In : Experimental Biology and Medicine. 243, 2, p. 198-210 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Pyruvic Acid
Pyruvates
Cardiopulmonary Bypass
Adenosine
Free energy
1 Citation (Scopus)

Pyruvate-enriched resuscitation for shock

Mallet, R. T., Yurvati, A. & Bünger, R., 1 May 2018, In : Experimental Biology and Medicine. 243, 8, p. 663-664 2 p.

Research output: Contribution to journalComment/debateResearch

Resuscitation
Pyruvic Acid
Shock
Hemorrhagic Shock
Bioelectric potentials
2017

Enhanced cerebral perfusion during brief exposures to cyclic intermittent hypoxemia

Liu, X., Xu, D., Hall, J. R., Ross, S. E., Chen, S., Liu, H., Mallet, R. T. & Shi, X., 1 Dec 2017, In : Journal of applied physiology (Bethesda, Md. : 1985). 123, 6, p. 1689-1697 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Perfusion
Oxygen
Middle Cerebral Artery
Vasodilation
Hypoxia
6 Citations (Scopus)

Erythropoietin: Endogenous Protection of Ischemic Brain

Mallet, R. T., Ryou, M. G. & Ryou, M. G., 1 Jan 2017, Vitamins and Hormones. Academic Press Inc., p. 197-232 36 p. (Vitamins and Hormones; vol. 105).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Erythropoietin
Brain
Ischemia
Heart Arrest
Brain Ischemia

Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest

Scott, G. F., Nguyen, A. Q., Cherry, B. H., Hollrah, R. A., Salinas, I., Williams, A. G., Ryou, M. G. & Mallet, R. T., 1 Jan 2017, In : Experimental Biology and Medicine. 242, 10, p. 1095-1103 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Resuscitation
Heart Arrest
Pyruvic Acid
Brain
Swine
5 Citations (Scopus)
Presenilin-1
Amyloid
Ethanol
Amyloid Precursor Protein Secretases
Heat-Shock Proteins
2016
9 Citations (Scopus)

Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease

Manukhina, E. B., Downey, H. F., Shi, X. & Mallet, R. T., 1 Jun 2016, In : Experimental Biology and Medicine. 241, 12, p. 1351-1363 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Alzheimer Disease
Cerebrovascular Circulation
Nitric Oxide
Pathology
Blood Vessels
4 Citations (Scopus)

Metabolomics and Receiver Operating Characteristic Analysis: A Promising Approach for Sepsis Diagnosis∗

Bünger, R. & Mallet, R. T., 1 Sep 2016, In : Critical Care Medicine. 44, 9, p. 1784-1785 2 p.

Research output: Contribution to journalEditorialResearch

Systemic Inflammatory Response Syndrome
Metabolomics
ROC Curve
Sepsis
9 Citations (Scopus)

δ-Opioid receptor (DOR) signaling and reactive oxygen species (ROS) mediate intermittent hypoxia induced protection of canine myocardium

Estrada, J. A., Williams, A. G., Sun, J., Gonzalez, L., Downey, H. F., Caffrey, J. L. & Mallet, R. T., 1 Mar 2016, In : Basic Research in Cardiology. 111, 2, p. 1-12 12 p., 17.

Research output: Contribution to journalArticleResearchpeer-review

Opioid Receptors
Canidae
Reactive Oxygen Species
Myocardium
Cardiac Arrhythmias
4 Citations (Scopus)

δ-Opioid receptors: Pivotal role in intermittent hypoxia-augmentation of cardiac parasympathetic control and plasticity

Estrada, J. A., Barlow, M. A., Yoshishige, D., Williams, A. G., Downey, H. F., Mallet, R. T. & Caffrey, J. L., 1 Jul 2016, In : Autonomic Neuroscience: Basic and Clinical. 198, p. 38-49 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Opioid Receptors
naltrindole
Vesicular Acetylcholine Transport Proteins
Adrenergic Agents
Cholinergic Agents
2015
2 Citations (Scopus)

Pyruvate stabilizes electrocardiographic and hemodynamic function in pigs recovering from cardiac arrest

Cherry, B. H., Nguyen, A. Q., Hollrah, R. A., Williams, A. G., Hoxha, B., Yurvati, A. & Mallet, R. T., 1 Dec 2015, In : Experimental Biology and Medicine. 240, 12, p. 1774-1784 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Hemodynamics
Heart Arrest
Pyruvic Acid
Swine
Recovery