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  • 2019
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  • Johnny He
2019
Open Access

Tat expression led to increased histone 3 tri-methylation at lysine 27 and contributed to HIV latency in astrocytes through regulation of MeCP2 and Ezh2 expression

Liu, Y., Niu, Y., Li, L., Timani, K. A., He, V. L., Sanburns, C., Xie, J. & He, J. J., 1 Aug 2019, In : Journal of NeuroVirology. 25, 4, p. 508-519 12 p.

Research output: Contribution to journalArticle

2018

Doxycycline-inducible and astrocyte-specific HIV-1 Tat transgenic mice (iTat) as an HIV/neuroAIDS model

Langford, D., Kim, B. O., Zou, W., Fan, Y., Rahimain, P., Liu, Y. & He, J. J., 15 Nov 2018, In : Journal of NeuroVirology. 24, 2, p. 168-179 12 p.

Research output: Contribution to journalReview article

9 Scopus citations

miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells

Liu, Y., Huang, X., Timani, K. A., Broxmeyer, H. E. & He, J. J., 1 Jan 2018, In : Oncotarget. 9, 4, p. 4823-4832 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neo-clerodane diterpenoids from the whole plants of Scutellaria formosana

Chen, X., Chen, W., Chen, G., Han, C., He, J. J., Zhou, X., Yu, Z., Dai, C. & Song, X., Jan 2018, In : Phytochemistry. 145, p. 1-9 9 p.

Research output: Contribution to journalArticle

Tip110/SART3 regulates IL-8 expression and predicts the clinical outcomes in melanoma

Timani, K. A., Gyorffy, B., Liu, Y., Mohammad, K. S. & He, J. J., 17 Aug 2018, In : Molecular Cancer. 17, 1, 124.

Research output: Contribution to journalLetter

2 Scopus citations
2017

HIV/neuroAIDS biomarkers

Rahimian, P. & He, J. J., Oct 2017, In : Progress in Neurobiology. 157, p. 117-132 16 p.

Research output: Contribution to journalReview article

9 Scopus citations

The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration

Fields, J. A., Metcalf, J., Overk, C., Adame, A., Spencer, B., Wrasidlo, W., Florio, J., Rockenstein, E., He, J. J. & Masliah, E., 1 Apr 2017, In : Journal of NeuroVirology. 23, 2, p. 290-303 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tip110 Deletion Impaired Embryonic and Stem Cell Development Involving Downregulation of Stem Cell Factors Nanog, Oct4, and Sox2

Whitmill, A., Liu, Y., Timani, K. A., Niu, Y. & He, J. J., Jul 2017, In : Stem Cells. 35, 7, p. 1674-1686 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Exosome-associated release, uptake, and neurotoxicity of HIV-1 Tat protein

Rahimian, P. & He, J. J., 1 Dec 2016, In : Journal of NeuroVirology. 22, 6, p. 774-788 15 p.

Research output: Contribution to journalArticle

28 Scopus citations

Function of ubiquitin (Ub) specific protease 15 (USP15) in HIV-1 replication and viral protein degradation

Pyeon, D., Timani, K. A., Gulraiz, F., He, J. J. & Park, I. W., 2 Sep 2016, In : Virus Research. 223, p. 161-169 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
25 Scopus citations

HIV-1 tat promotes lysosomal exocytosis in astrocytes and contributes to astrocyte-mediated tat neurotoxicity

Fan, Y. & He, J. J., 21 Oct 2016, In : Journal of Biological Chemistry. 291, 43, p. 22830-22840 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

HIV-1 Tat-shortened neurite outgrowth through regulation of microRNA-132 and its target gene expression

Rahimian, P. & He, J. J., 15 Sep 2016, In : Journal of neuroinflammation. 13, 1, 247.

Research output: Contribution to journalArticle

18 Scopus citations

HIV Tat impairs neurogenesis through functioning as a notch ligand and activation of notch signaling pathway

Fan, Y., Gao, X., Chen, J., Liu, Y. & He, J. J., 2 Nov 2016, In : Journal of Neuroscience. 36, 44, p. 11362-11373 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Role of Tat-interacting protein of 110kDa and microRNAs in the regulation of hematopoiesis

Liu, Y. & He, J. J., 1 Jul 2016, In : Current Opinion in Hematology. 23, 4, p. 325-330 6 p.

Research output: Contribution to journalReview article

Tip110: Physical properties, primary structure, and biological functions

Whitmill, A., Timani, K. A., Liu, Y. & He, J. J., 15 Mar 2016, In : Life Sciences. 149, p. 79-95 17 p.

Research output: Contribution to journalReview article

9 Scopus citations
2015

Exosomes are unlikely involved in intercellular Nef transfer

Luo, X., Fan, Y., Park, I. W. & He, J. J., 28 Apr 2015, In : PLoS ONE. 10, 4, e0124436.

Research output: Contribution to journalArticle

26 Scopus citations

HIV-1 tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: Implications for HIV-associated neurocognitive disorders

Fields, J., Dumaop, W., Elueteri, S., Campos, S., Serger, E., Trejo, M., Kosberg, K., Adame, A., Spencer, B., Rockenstein, E., He, J. J. & Masliah, E., 1 Jan 2015, In : Journal of Neuroscience. 35, 5, p. 1921-1938 18 p.

Research output: Contribution to journalArticle

56 Scopus citations

Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase

Visalli, R. J., Ziobrowski, H., Badri, K. R., He, J. J., Zhang, X., Arumugam, S. R. & Zhao, H., 3 Jul 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 16, p. 3168-3171 4 p., 22789.

Research output: Contribution to journalArticle

9 Scopus citations

Mechanisms of HIV-1 tat neurotoxicity via CDK5 translocation and hyper-activation: Role in HIV-associated neurocognitive disorders

Fields, J. A., Dumaop, W., Crews, L., Adame, A., Spencer, B., Metcalf, J., He, J., Rockenstein, E. & Masliah, E., 1 Jan 2015, In : Current HIV Research. 13, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

MicroRNA-124 Targets Tip110 Expression and Regulates Hematopoiesis

Liu, Y., Huang, X., Timani, K. A., Broxmeyer, H. E. & He, J. J., 1 Sep 2015, In : Stem Cells and Development. 24, 17, p. 2009-2017 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

STAT3 and its phosphorylation are involved in HIV-1 tat-induced transactivation of glial fibrillary acidic protein

Fan, Y., Timani, K. A. & He, J. J., 1 Jan 2015, In : Current HIV Research. 13, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Tip110 binding to U6 small nuclear RNA and its participation in pre-mRNA splicing

Liu, Y., Liu, J., Wang, Z. & He, J. J., 23 Jul 2015, In : Cell and Bioscience. 5, 1, 40.

Research output: Contribution to journalArticle

4 Scopus citations

Tip110 regulates the cross talk between p53 and hypoxia-inducible factor 1α under hypoxia and promotes survival of cancer cells

Timani, K. A., Liu, Y., Fan, Y., Mohammad, K. S. & He, J. J., 1 Jan 2015, In : Molecular and Cellular Biology. 35, 13, p. 2254-2264 11 p.

Research output: Contribution to journalArticle

11 Scopus citations