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2019
1 Citation (Scopus)

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R. M., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Medulloblastoma
Vincristine
tolfenamic acid
Cell Cycle
Apoptosis
2018

Early Nutrition Intervention Attenuates Weight Gain for Pediatric Acute Lymphoblastic Leukemia Patients in Maintenance Therapy

Hill, R., Hamby, T., Bashore, L., Rapisand, S., Galipp, K., Heym, K. & Bowman, P., 1 Jan 2018, In : Journal of Pediatric Hematology/Oncology. 40, 2, p. 104-110 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Weight Gain
Pediatrics
Therapeutics
Body Mass Index
16 Citations (Scopus)

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

Churchman, M. L., Qian, M., te Kronnie, G., Zhang, R., Yang, W., Zhang, H., Lana, T., Tedrick, P., Baskin, R., Verbist, K., Peters, J. L., Devidas, M., Larsen, E., Moore, I. M., Gu, Z., Qu, C., Yoshihara, H., Porter, S. N., Pruett-Miller, S. M., Wu, G. & 16 others, Raetz, E., Martin, P. L., Bowman, P., Winick, N., Mardis, E., Fulton, R., Stanulla, M., Evans, W. E., Relling, M. V., Pui, C. H., Hunger, S. P., Loh, M. L., Handgretinger, R., Nichols, K. E., Yang, J. J. & Mullighan, C. G., 14 May 2018, In : Cancer Cell. 33, 5, p. 937-948.e8

Research output: Contribution to journalArticleResearchpeer-review

Genetic Predisposition to Disease
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cell Communication
Computer Simulation
Protein-Tyrosine Kinases

Therapeutic leukocytapheresis in infants and children with leukemia and hyperleukocytosis: A single institution experience

Thapa, N., Pham, R., Cole, C., Meinershagen, M., Bowman, P. & Ray, A., 1 Jun 2018, In : Journal of Clinical Apheresis. 33, 3, p. 316-323 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Leukapheresis
Leukemia
Leukocyte Count
Pediatrics
Therapeutics
22 Citations (Scopus)

TP53 germline variations influence the predisposition and prognosis of b-cell acute lymphoblastic leukemia in children

Qian, M., Cao, X., Devidas, M., Yang, W., Cheng, C., Dai, Y., Carroll, A., Heerema, N. A., Zhang, H., Moriyama, T., Gastier-Foster, J. M., Xu, H., Raetz, E., Larsen, E., Winick, N., Bowman, P., Martin, P. L., Mardis, E. R., Fulton, R., Zambetti, G. & 11 others, Borowitz, M., Wood, B., Nichols, K. E., Carroll, W. L., Pui, C. H., Mullighan, C. G., Evans, W. E., Hunger, S. P., Relling, M. V., Loh, M. L. & Yang, J. J., 20 Feb 2018, In : Journal of Clinical Oncology. 36, 6, p. 591-599 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Li-Fraumeni Syndrome
Second Primary Neoplasms
Computer Simulation
Disease-Free Survival
2017
29 Citations (Scopus)

Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with Response-Adapted therapy

Pui, C. H., Pei, D., Raimondi, S. C., Coustan-Smith, E., Jeha, S., Cheng, C., Bowman, P., Sandlund, J. T., Ribeiro, R. C., Rubnitz, J. E., Inaba, H., Gruber, T. A., Leung, W. H., Yang, J. J., Downing, J. R., Evans, W. E., Relling, M. V. & Campana, D., 1 Feb 2017, In : Leukemia. 31, 2, p. 333-339 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
National Cancer Institute (U.S.)
Biphenotypic Acute Leukemia
Polyploidy
1 Citation (Scopus)

Pleuropulmonary blastoma: A single-center case series of 6 patients

Pierce, J. M., Lacroix, P., Heym, K., Bowman, P., Margraf, L., Iglesias, J. & Ray, A., 1 Jan 2017, In : Journal of Pediatric Hematology/Oncology. 39, 8, p. e419-e422

Research output: Contribution to journalArticleResearchpeer-review

Neoplasms
Therapeutics
Lung
Mutation
Germ-Line Mutation
10 Citations (Scopus)

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth

Shelake, S., Sankpal, U. T., Bowman, P., Wise, M., Ray, A. & Basha, R. M., 1 Apr 2017, In : Investigational New Drugs. 35, 2, p. 158-165 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Sp1 Transcription Factor
Ewing's Sarcoma
Growth
Neoplasms
Proteasome Inhibitors
2016
26 Citations (Scopus)

Clinical and genetic risk factors for acute pancreatitis in patients with acute lymphoblastic leukemia

Liu, C., Yang, W., Devidas, M., Cheng, C., Pei, D., Smith, C., Carroll, W. L., Raetz, E. A., Bowman, P., Larsen, E. C., Maloney, K. W., Martin, P. L., Mattano, L. A., Winick, N. J., Mardis, E. R., Fulton, R. S., Bhojwani, D., Howard, S. C., Jeha, S., Pui, C. H. & 4 others, Hunger, S. P., Evans, W. E., Loh, M. L. & Relling, M. V., 20 Jun 2016, In : Journal of Clinical Oncology. 34, 18, p. 2133-2140 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pancreatitis
Asparaginase
North American Indians
Genome-Wide Association Study

Correlation of Lipid Profile and Risk of Developing Type 2 Diabetes Mellitus in 10-14 Year Old Children

Habiba, N. M., Fulda, K. G., Basha, R. M., Shah, D., Fernando, S., Nguyen, B., Xiong, Y., Franks, S. F., Matches, S., Magie, R. D. & Bowman, P., 1 Nov 2016, In : Cellular Physiology and Biochemistry. 39, 5, p. 1695-1704 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Type 2 Diabetes Mellitus
Lipids
Social Class
Logistic Models
Cholesterol
2015
66 Citations (Scopus)

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: A prospective study

Pui, C. H., Pei, D., Coustan-Smith, E., Jeha, S., Cheng, C., Bowman, P., Sandlund, J. T., Ribeiro, R. C., Rubnitz, J. E., Inaba, H., Bhojwani, D., Gruber, T. A., Leung, W. H., Downing, J. R., Evans, W. E., Relling, M. V. & Campana, D., 1 Jan 2015, In : The Lancet Oncology. 16, 4, p. 465-474 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prospective Studies
Remission Induction
Therapeutics
5 Citations (Scopus)

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

Shelake, S., Eslin, D., Sutphin, R. M., Sankpal, U. T., Wadwani, A., Kenyon, L. E., Tabor-Simecka, L., Bowman, P., Vishwanatha, J. K. & Basha, R. M., 1 Nov 2015, In : International Journal of Developmental Neuroscience. 46, p. 92-99 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Isotretinoin
Neuroblastoma
Tretinoin
Cell Proliferation
Apoptosis
31 Citations (Scopus)

Genome-wide analysis links NFATC2 with asparaginase hypersensitivity

Fernandez, C. A., Smith, C., Yang, W., Mullighan, C. G., Qu, C., Larsen, E., Bowman, P., Liu, C., Ramsey, L. B., Chang, T., Karol, S. E., Loh, M. L., Raetz, E. A., Winick, N. J., Hunger, S. P., Carroll, W. L., Jeha, S., Pui, C. H., Evans, W. E., Devidas, M. & 1 others, Relling, M. V., 2 Jul 2015, In : Blood. 126, 1, p. 69-75 7 p.

Research output: Contribution to journalArticleResearchpeer-review

NFATC Transcription Factors
Asparaginase
Hypersensitivity
Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma
55 Citations (Scopus)

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: A systematic genetic study

Moriyama, T., Metzger, M. L., Wu, G., Nishii, R., Qian, M., Devidas, M., Yang, W., Cheng, C., Cao, X., Quinn, E., Raimondi, S., Gastier-Foster, J. M., Raetz, E., Larsen, E., Martin, P. L., Bowman, P., Winick, N., Komada, Y., Wang, S., Edmonson, M. & 12 others, Xu, H., Mardis, E., Fulton, R., Pui, C. H., Mullighan, C., Evans, W. E., Zhang, J., Hunger, S. P., Relling, M. V., Nichols, K. E., Loh, M. L. & Yang, J. J., 1 Jan 2015, In : The Lancet Oncology. 16, 16, p. 1659-1666 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Exome
Charities
Erythroblasts
28 Citations (Scopus)

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, J. C., Mardis, E., Fulton, R., Pui, C. H., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, K., Loh, M. L., Relling, M. V. & Yang, J. J., 24 Jun 2015, In : Nature Communications. 6, 7553.

Research output: Contribution to journalArticleResearchpeer-review

leukemias
loci
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tumors
coding
33 Citations (Scopus)

Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels

Mullighan, C. G., Jeha, S., Pei, D., Payne-Turner, D., Coustan-Smith, E., Roberts, K. G., Waanders, E., Choi, J. K., Ma, X., Raimondi, S. C., Fan, Y., Yang, W., Song, G., Yang, J. J., Inaba, H., Downing, J. R., Leung, W. H., Bowman, P., Relling, M. V., Evans, W. E. & 3 others, Zhang, J., Campana, D. & Pui, C. H., 24 Dec 2015, In : Blood. 126, 26, p. 2896-2899 4 p.

Research output: Contribution to journalLetterResearchpeer-review

12 Citations (Scopus)

Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy

Karol, S. E., Coustan-Smith, E., Cao, X., Shurtleff, S. A., Raimondi, S. C., Choi, J. K., Ribeiro, R. C., Dahl, G. V., Bowman, P., Taub, J. W., Degar, B., Leung, W., Downing, J. R., Pui, C. H., Rubnitz, J. E., Campana, D. & Inaba, H., 1 Jan 2015, In : British Journal of Haematology. 168, 1, p. 94-101 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Remission Induction
Residual Neoplasm
Acute Myeloid Leukemia
Leukemia, Megakaryoblastic, Acute
Therapeutics
23 Citations (Scopus)

Subclinical cardiotoxicity in childhood cancer survivors exposed to very low dose anthracycline therapy

Leger, K., Slone, T., Lemler, M., Leonard, D., Cochran, C., Bowman, P., Bashore, L. & Winick, N., 1 Jan 2015, In : Pediatric Blood and Cancer. 62, 1, p. 123-127 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Anthracyclines
Survivors
Neoplasms
Therapeutics
Left Ventricular Function
6 Citations (Scopus)

Universal cholesterol screening of children in community-based ambulatory pediatric clinics

Wilson, D. P., Davis, S., Matches, S., Shah, D., Leung-Pineda, V., Mou, M., Hamilton, L., McNeal, C. J. & Bowman, P., 1 Sep 2015, In : Journal of Clinical Lipidology. 9, 5, p. S88-S92 766.

Research output: Contribution to journalArticleResearchpeer-review

National Heart, Lung, and Blood Institute (U.S.)
Cholesterol
Pediatrics
Publications
Hyperlipoproteinemia Type II
27 Citations (Scopus)

Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids

Kaste, S. C., Pei, D., Cheng, C., Neel, M. D., Bowman, P., Ribeiro, R. C., Metzger, M. L., Bhojwani, D., Inaba, H., Campbell, P., Rubnitz, J. E., Jeha, S., Sandlund, J. T., Downing, J. R., Relling, M. V., Pui, C. H. & Howard, S. C., 20 Feb 2015, In : Journal of Clinical Oncology. 33, 6, p. 610-615 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Osteonecrosis
Glucocorticoids
Hip
Magnetic Resonance Imaging
Pediatrics