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2019

A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Phenotype
Serum
Fibroblast Growth Factor 2
Epidermal Growth Factor
2018
3 Citations (Scopus)

Artemisinin prevents glutamate-induced neuronal cell death via Akt pathway activation

Lin, S. P., Li, W., Winters, A., Liu, R. & Yang, S., 20 Apr 2018, In : Frontiers in Cellular Neuroscience. 12, 108.

Research output: Contribution to journalArticleResearchpeer-review

Glutamic Acid
Cell Death
artemisinine
Mitochondrial Membrane Potential
Antimalarials
2 Citations (Scopus)

Experimental ischemic stroke induces long-term T cell activation in the brain

Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S., 1 Jan 2018, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticleResearchpeer-review

Stroke
T-Lymphocytes
Brain
Perforin
Interleukin-17
3 Citations (Scopus)

Hyperglycemia alters astrocyte metabolism and inhibits astrocyte proliferation

Li, W., Choudhury, G. R., Winters, A., Prah, J., Lin, W., Liu, R. & Yang, S., 1 Jan 2018, In : Aging and Disease. 9, 4, p. 674-684 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Hyperglycemia
Glucose
Energy Metabolism
Cyclin D3
1 Citation (Scopus)

Precision Medicine for Ischemic Stroke, Let Us Move Beyond Time Is Brain

Yang, S., Lou, M., Luo, B., Jiang, W. J. & Liu, R., 1 Apr 2018, In : Translational Stroke Research. 9, 2, p. 93-95 3 p.

Research output: Contribution to journalEditorialResearch

Precision Medicine
Stroke
Brain
2017
4 Citations (Scopus)

Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury

Wu, J., Li, R., Li, W., Ren, M., Thangthaeng, N., Sumien, N., Liu, R., Yang, S., Simpkins, J. W., Forster, M. J. & Yan, L-J., 1 Dec 2017, In : Free Radical Biology and Medicine. 113, p. 244-254 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Dihydrolipoamide Dehydrogenase
Ischemic Preconditioning
Stroke
Wounds and Injuries
5-methoxyindole-2-carboxylic acid
15 Citations (Scopus)

Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots

Yang, S., Li, W., Sumien, N., Forster, M. J., Simpkins, J. W. & Liu, R., 1 Oct 2017, In : Progress in Neurobiology. 157, p. 273-291 19 p.

Research output: Contribution to journalReview articleResearchpeer-review

Methylene Blue
Neurodegenerative Diseases
Electrons
Energy Metabolism
Oxidative Phosphorylation
1 Citation (Scopus)

Cerebral Autoregulation

Yang, S. & Liu, R., 7 Mar 2017, Primer on Cerebrovascular Diseases: Second Edition. Elsevier Inc., p. 57-60 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Homeostasis
Cerebrovascular Circulation
Arterial Pressure
Blood Pressure
Brain

Methylene blue inhibits GABAA receptors by interaction with GABA binding site

Chen, Z., Liu, R., Yang, S., Dillon, G. H. & Huang, R-Q., 1 Jun 2017, In : Neuropharmacology. 119, p. 100-110 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Methylene Blue
GABA-A Receptors
gamma-Aminobutyric Acid
Binding Sites
Picrotoxin
2016
1 Citation (Scopus)

For the pursuit of oxygen and carbon dioxide channels in mitochondria

Yang, S. & Liu, R., 1 Oct 2016, In : Medical Gas Research. 6, 4, p. 237-238 2 p.

Research output: Contribution to journalEditorialResearch

Carbon Dioxide
Mitochondria
Oxygen
8 Citations (Scopus)

Methylene blue ameliorates ischemia/reperfusion-induced cerebral edema: An MRI and transmission electron microscope study

Fang, Q., Yan, X., Li, S., Sun, Y., Xu, L., Shi, Z., Wu, M., Lu, Y., Dong, L., Liu, R., Yuan, F. & Yang, S., 1 Jan 2016, Acta Neurochirurgica, Supplementum. Springer-Verlag Wien, p. 227-236 10 p. (Acta Neurochirurgica, Supplementum; vol. 121).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Methylene Blue
Middle Cerebral Artery Infarction
Transient Ischemic Attack
Brain Edema
Neuroprotective Agents
6 Citations (Scopus)

Neuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism

Cai, B., Li, W., Mao, X. O., Winters, A., Ryou, M. G., Liu, R., Greenberg, D. A., Wang, N., Jin, K. & Yang, S., 1 Mar 2016, In : Molecular Neurobiology. 53, 2, p. 1254-1265 12 p.

Research output: Contribution to journalArticleResearchpeer-review

AMP-Activated Protein Kinases
Glycogen
Globins
Neurons
Brain
2015
14 Citations (Scopus)

Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas

He, W., Liu, R., Yang, S. & Yuan, F., 1 Jan 2015, In : Anti-Cancer Drugs. 26, 3, p. 293-300 8 p.

Research output: Contribution to journalArticleResearchpeer-review

temozolomide
Tamoxifen
Glioma
Cell Line
Apoptosis
30 Citations (Scopus)

Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress

Ryou, M. G., Choudhury, G. R., Li, W., Winters, A., Yuan, F., Liu, R. & Yang, S., 1 Aug 2015, In : Neuroscience. 301, p. 193-203 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypoxia-Inducible Factor 1
Methylene Blue
Glucose
Erythropoietin
Oxygen
14 Citations (Scopus)

Methylene blue protects astrocytes against glucose oxygen deprivation by improving cellular respiration

Choudhury, G. R., Winters, A., Rich, R. M., Ryou, M. G., Gryczynski, Z., Yuan, F., Yang, S. & Liu, R., 7 Apr 2015, In : PLoS ONE. 10, 4, e0123096.

Research output: Contribution to journalArticleResearchpeer-review

Cell Respiration
methylene blue
Methylene Blue
astrocytes
cell respiration