Find Research Outputs

Search concepts
Selected Filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2011
  • 2010

Author

  • Liang-Jun Yan
2019

Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress

Yang, X., Song, J. & Yan, L. J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Circulating factors in young blood as potential therapeutic agents for age-related neurodegenerative and neurovascular diseases

Ma, J., Gao, B., Zhang, K., Zhang, Q., Jia, G., Li, J., Li, C., Yan, L. J. & Cai, Z., Nov 2019, In : Brain Research Bulletin. 153, p. 15-23 9 p.

Research output: Contribution to journalReview article

Role of Catalase in Oxidative Stress- And Age-Associated Degenerative Diseases

Nandi, A., Yan, L. J., Jana, C. K. & Das, N., 1 Jan 2019, In : Oxidative Medicine and Cellular Longevity. 2019, 9613090.

Research output: Contribution to journalArticle

Open Access
Open Access
5 Scopus citations

Vagus nerve stimulation as a promising adjunctive treatment for ischemic stroke

Ma, J., Qiao, P., Li, Q., Wang, Y., Zhang, L., Yan, L. J. & Cai, Z., Dec 2019, In : Neurochemistry International. 131, 104539.

Research output: Contribution to journalReview article

2018

Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease

Zhao, Y. S., Zhang, L. H., Yu, P. P., Gou, Y. J., Zhao, J., You, L. H., Wang, Z. Y., Zheng, X., Yan, L. J., Yu, P. & Chang, Y. Z., 10 May 2018, In : Antioxidants and Redox Signaling. 28, 14, p. 1323-1337 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway

Yang, X., Zhang, H., Wu, J., Yin, L., Yan, L. J. & Zhang, C., Oct 2018, In : International journal of molecular sciences. 19, 10, 2982.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations
2 Scopus citations

Role and possible mechanisms of sirt1 in depression

Lu, G., Li, J., Zhang, H., Zhao, X., Yan, L. J. & Yang, X., 1 Jan 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 8596903.

Research output: Contribution to journalReview article

13 Scopus citations
2017
5 Scopus citations

Non-gradient blue native polyacrylamide gel electrophoresis

Luo, X., Wu, J., Jin, Z. & Yan, L. J., 1 Feb 2017, In : Current Protocols in Protein Science. 2017, p. 19.29.1-19.29.12

Research output: Contribution to journalArticle

4 Scopus citations

Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes

Wu, J., Luo, X., Thangthaeng, N., Sumien, N., Chen, Z., Rutledge, M. A., Jing, S., Forster, M. J. & Yan, L. J., Sep 2017, In : Biochemistry and Biophysics Reports. 11, p. 119-129 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Potential biochemical mechanisms of lung injury in diabetes

Zheng, H., Wu, J., Jin, Z. & Yan, L. J., 1 Jan 2017, In : Aging and Disease. 8, 1, p. 7-16 10 p.

Research output: Contribution to journalReview article

14 Scopus citations

Redox imbalance and mitochondrial abnormalities in the diabetic lung

Wu, J., Jin, Z. & Yan, L. J., 1 Apr 2017, In : Redox Biology. 11, p. 51-59 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity

Yang, X., Si, P., Qin, H., Yin, L., Yan, L. J. & Zhang, C., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 2823454.

Research output: Contribution to journalArticle

11 Scopus citations
2016

Chemical conditioning as an approach to ischemic stroke tolerance: Mitochondria as the target

Jin, Z., Wu, J. & Yan, L. J., 8 Mar 2016, In : International journal of molecular sciences. 17, 3, 351.

Research output: Contribution to journalReview article

17 Scopus citations

Chronic mTOR Inhibition by Rapamycin and Diabetes: What is the Role of Mitochondria?

Yan, L. J. & Cai, Z., 26 Feb 2016, Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies. Elsevier Inc., p. 365-378 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes

Dong, K., Wu, M., Liu, X., Huang, Y., Zhang, D., Wang, Y., Yan, L. J. & Shi, D., 1 Dec 2016, In : Free Radical Biology and Medicine. 101, p. 334-347 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Hyperglycemic stress and carbon stress in diabetic glucotoxicity

Luo, X., Wu, J., Jing, S. & Yan, L. J., Feb 2016, In : Aging and Disease. 7, 1, p. 90-110 21 p.

Research output: Contribution to journalArticle

43 Scopus citations

Role of RAGE in Alzheimer’s Disease

Cai, Z., Liu, N., Wang, C., Qin, B., Zhou, Y., Xiao, M., Chang, L., Yan, L. J. & Zhao, B., 1 May 2016, In : Cellular and Molecular Neurobiology. 36, 4, p. 483-495 13 p.

Research output: Contribution to journalReview article

80 Scopus citations

Sources and implications of NADH/NAD+ redox imbalance in diabetes and its complications

Wu, J., Jin, Z., Zheng, H. & Yan, L. J., 10 May 2016, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 9, p. 145-153 9 p.

Research output: Contribution to journalReview article

21 Scopus citations
6 Scopus citations
2015

Activation of mTOR: A culprit of Alzheimer’s disease?

Cai, Z., Chen, G., He, W., Xiao, M. & Yan, L. J., 9 Apr 2015, In : Neuropsychiatric Disease and Treatment. 11, p. 1015-1030 16 p.

Research output: Contribution to journalArticle

54 Scopus citations
14 Scopus citations

Cerebral small vessel disease and Alzheimer’s disease

Cai, Z., Wang, C., He, W., Tu, H., Tang, Z., Xiao, M. & Yan, L. J., 1 Jan 2015, In : Clinical interventions in aging. 10, p. 1695-1704 10 p., A196.

Research output: Contribution to journalReview article

31 Scopus citations

Mitochondrial dihydrolipoamide dehydrogenase is upregulated in response to intermittent hypoxic preconditioning

Li, R., Luo, X., Wu, J., Thangthaeng, N., Jung, M. E., Jing, S., Li, L., Ellis, D. Z., Liu, L., Ding, Z., Forster, M. J. & Yan, L. J., 23 May 2015, In : International Journal of Medical Sciences. 12, 5, p. 432-440 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Role of insulin resistance in Alzheimer’s disease

Cai, Z., Xiao, M., Chang, L. & Yan, L. J., 1 Aug 2015, In : Metabolic Brain Disease. 30, 4, p. 839-851 13 p., A001.

Research output: Contribution to journalReview article

16 Scopus citations

Roles of Pyruvate, NADH, and Mitochondrial Complex i in Redox Balance and Imbalance in β Cell Function and Dysfunction

Luo, X., Li, R. & Yan, L. J., 1 Jan 2015, In : Journal of Diabetes Research. 2015, 512618.

Research output: Contribution to journalReview article

24 Scopus citations
71 Scopus citations

Two dimensional blue native/SDS-PAGE to identify mitochondrial complex I subunits modified by 4-hydroxynonenal (HNE)

Wu, J., Luo, X. & Yan, L. J., 1 Jan 2015, In : Frontiers in Physiology. 6, MAR, 098.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Cancer-Associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and D-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia

Reitman, Z. J., Duncan, C. G., Poteet, E., Winters, A., Yan, L. J., Gooden, D. M., Spasojevic, I., Boros, L. G., Yang, S. H. & Yan, H., 1 Jan 2014, In : Journal of Biological Chemistry. 289, 34, p. 23318-23328 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Diagonal gel electrophoretic analysis of protein disulfides: Principles and applications

Luo, X., Li, R. & Yan, L. J., 1 Oct 2014, Reactive Oxygen Species, Lipid Peroxidation and Protein Oxidation. Nova Science Publishers, Inc., p. 87-94 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease

Cai, Z., Hussain, M. D. & Yan, L. J., May 2014, In : International Journal of Neuroscience. 124, 5, p. 307-321 15 p.

Research output: Contribution to journalReview article

143 Scopus citations

Pathogenesis of chronic hyperglycemia: From reductive stress to oxidative stress

Yan, L. J., 2014, In : Journal of Diabetes Research. 2014, 137919.

Research output: Contribution to journalReview article

125 Scopus citations

Positive oxidative stress in aging and aging-related disease tolerance

Yan, L. J., Apr 2014, In : Redox Biology. 2, 1, p. 165-169 5 p.

Research output: Contribution to journalReview article

83 Scopus citations
20 Scopus citations

PTEN degradation after ischemic stroke: A double-edged sword

Li, W., Huang, R., Chen, Z., Yan, L. J., Simpkins, J. W. & Yang, S. H., 22 Aug 2014, In : Neuroscience. 274, p. 153-161 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013

Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide.

Yan, L. J., Sumien, N., Thangthaeng, N. & Forster, M. J., Feb 2013, In : Unknown Journal. 47, 2, p. 123-133 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Telomere Shortening and Alzheimer's Disease

Cai, Z., Yan, L. J. & Ratka, A., 1 Mar 2013, In : NeuroMolecular Medicine. 15, 1, p. 25-48 24 p.

Research output: Contribution to journalReview article

50 Scopus citations
2011

Alternative mitochondrial electron transfer as a novel strategy for neuroprotection

Wen, Y., Li, W., Poteet, E. C., Xie, L., Tan, C., Yan, L. J., Ju, X., Liu, R., Qian, H., Marvin, M. A., Goldberg, M. S., She, H., Mao, Z., Simpkins, J. W. & Yang, S. H., 6 May 2011, In : Journal of Biological Chemistry. 286, 18, p. 16504-16515 12 p.

Research output: Contribution to journalArticle

149 Scopus citations
63 Scopus citations

Ethanol withdrawal acts as an age-specific stressor to activate cerebellar P38 kinase

Jung, M. E., Ju, X., Simpkins, J. W., Metzger, D. B., Yan, L. J. & Wen, Y., 1 Dec 2011, In : Neurobiology of Aging. 32, 12, p. 2266-2278 13 p.

Research output: Contribution to journalArticle

11 Scopus citations
11 Scopus citations