Find Research Outputs

Search concepts
Selected Filters
2019

Comparison of diabetic nephropathy between male and female eNOS-/- db/db mice

Ma, Y., Li, W., Shotorbani, P. Y., Dubansky, B. H., Huang, L., Chaudhari, S., Wu, P., Wang, L. A., Ryou, M. G., Zhou, Z. & Ma, R., 1 May 2019, In : American Journal of Physiology - Renal Physiology. 316, 5, p. F889-F897

Research output: Contribution to journalArticleResearchpeer-review

Diabetic Nephropathies
Sex Characteristics
Kidney
Physiological Phenomena
Albuminuria
2018

Short-term high-glucose treatment decreased abundance of Orai1 protein through posttranslational mechanisms in rat Mesangial cells

Jiang, H., Zou, S., Chaudhari, S. & Ma, R., 1 Jan 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F855-F863

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glucose
Proteins
Ubiquitination
Period Circadian Proteins
2017
4 Citations (Scopus)

Effects of Shu Gan Jian Pi formula on rats with carbon tetrachloride-induced Liver fibrosis using serum metabonomics based on gas chromatography-time of flight mass spectrometry

Jiang, H., Qin, X. J., Li, W. P., Ma, R., Wang, T. & Li, Z. Q., 1 Oct 2017, In : Molecular Medicine Reports. 16, 4, p. 3901-3909 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics
Carbon Tetrachloride
Liver Cirrhosis
Gas chromatography
Gas Chromatography
3 Citations (Scopus)

Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice

Li, W., Ding, Y., Smedley, C., Wang, Y., Chaudhari, S., Birnbaumer, L. & Ma, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 4145.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glomerular Filtration Rate
Knockout Mice
Kidney
Small Interfering RNA
4 Citations (Scopus)

Negative regulation of smad1 pathway and collagen IV expression by store-operated Ca2+ entry in glomerular mesangial cells

Wu, P., Ren, Y., Ma, Y., Wang, Y., Jiang, H., Chaudhari, S., Davis, M. E., Zuckerman, J. E. & Ma, R., 4 Jun 2017, In : American Journal of Physiology - Renal Physiology. 312, 6, p. F1090-F1100

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Collagen
Smad1 Protein
Small Interfering RNA
Proteins
14 Citations (Scopus)

Reconstruction and analysis of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal functional lncRNAs in rheumatoid arthritis

Jiang, H., Ma, R., Zou, S., Wang, Y., Li, Z. & Li, W., 1 Jan 2017, In : Molecular BioSystems. 13, 6, p. 1182-1192 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Long Noncoding RNA
MicroRNAs
Rheumatoid Arthritis
RNA
Messenger RNA
2 Citations (Scopus)

Store-operated calcium entry suppressed the TGF-β1/Smad3 signaling pathway in glomerular mesangial cells

Chaudhari, S., Li, W., Wang, Y., Jiang, H., Ma, Y., Davis, M. E., Zuckerman, J. E. & Ma, R., 11 Sep 2017, In : American Journal of Physiology - Renal Physiology. 313, 3, p. F729-F739

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Transforming Growth Factors
Thapsigargin
Calcium
Phosphorylation
2016
12 Citations (Scopus)

Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology

Ma, R., Chaudhari, S. & Li, W., 1 Nov 2016, In : Antioxidants and Redox Signaling. 25, 13, p. 732-748 17 p.

Research output: Contribution to journalReview articleResearchpeer-review

Transient Receptor Potential Channels
Physiology
Pathology
Reactive Oxygen Species
Kidney
14 Citations (Scopus)

Danshensu protects against ischemia/reperfusion injury and inhibits the apoptosis of H9c2 cells by reducing the calcium overload through the p-JNK-NF-κB-TRPC6 pathway

Meng, Y., Li, W. Z., Shi, Y. W., Zhou, B. F., Ma, R. & Li, W. P., 1 Jan 2016, In : International journal of molecular medicine. 37, 1, p. 258-266 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Reperfusion Injury
Phosphotransferases
Apoptosis
Calcium
Incubators
10 Citations (Scopus)

LncRNAs expression in adjuvant-induced arthritis rats reveals the potential role of LncRNAs contributing to rheumatoid arthritis pathogenesis

Jiang, H., Qin, X. J., Li, W. P., Ma, R., Wang, T. & Li, Z. Q., 15 Nov 2016, In : Gene. 593, 1, p. 131-142 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Long Noncoding RNA
Experimental Arthritis
Rheumatoid Arthritis
Real-Time Polymerase Chain Reaction
Gene Expression
7 Citations (Scopus)

Store-operated calcium entry and diabetic complications

Chaudhari, S. & Ma, R., 1 Feb 2016, In : Experimental Biology and Medicine. 241, 4, p. 343-352 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Diabetes Complications
Medical problems
Calcium
Diabetic Nephropathies
Receptor Protein-Tyrosine Kinases
2015
4 Citations (Scopus)

Impairment of hepatic nuclear factor-4α binding to the stim1 promoter contributes to high glucose-induced upregulation of stim1 expression in glomerular mesangial cells

Wang, Y., Chaudhari, S., Ren, Y. & Ma, R., 15 May 2015, In : American Journal of Physiology - Renal Physiology. 308, 10, p. F1135-F1145

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Up-Regulation
Glucose
Liver
Diabetic Nephropathies
17 Citations (Scopus)

SiRNA delivery to the glomerular mesangium using polycationic cyclodextrin nanoparticles containing siRNA

Zuckerman, J. E., Gale, A., Wu, P., Ma, R. & Davis, M. E., 1 Apr 2015, In : Nucleic Acid Therapeutics. 25, 2, p. 53-64 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Glomerular Mesangium
Cyclodextrins
Nanoparticles
Small Interfering RNA
Cytidine Diphosphate
12 Citations (Scopus)

Store-operated Ca2+ channels in mesangial cells inhibit matrix protein expression

Wu, P., Wang, Y., Davis, M. E., Zuckerman, J. E., Chaudhari, S., Begg, M. & Ma, R., 1 Nov 2015, In : Journal of the American Society of Nephrology. 26, 11, p. 2691-2702 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Fibronectins
Collagen
Proteins
Thapsigargin
2014
39 Citations (Scopus)

Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli

Ilatovskaya, D. V., Palygin, O., Chubinskiy-Nadezhdin, V., Negulyaev, Y. A., Ma, R., Birnbaumer, L. & Staruschenko, A., 1 Jan 2014, In : Kidney International. 86, 3, p. 506-514 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Podocytes
Angiotensin II
Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
TRPC Cation Channels
30 Citations (Scopus)

Astragaloside IV prevents damage to human mesangial cells through the inhibition of the NADPH oxidase/ROS/Akt/NF-κB pathway under high glucose conditions

Sun, L. I., Li, W., Li, W., Xiong, L. I., Li, G. & Ma, R., 1 Jan 2014, In : International journal of molecular medicine. 34, 1, p. 167-176 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
NADP
Reactive Oxygen Species
Oxidoreductases
Glucose
28 Citations (Scopus)

High glucose and diabetes enhanced store-operated Ca2+ entry and increased expression of its signaling proteins in mesangial cells

Chaudhari, S., Wu, P., Wang, Y., Ding, Y., Yuan, J. P., Begg, M. & Ma, R., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glucose
Proteins
Cultured Cells
Inositol 1,4,5-Trisphosphate
64 Citations (Scopus)

MiR-9 promotes microglial activation by targeting MCPIP1

Yao, H., Ma, R., Yang, L., Hu, G., Chen, X., Duan, M., Kook, Y., Niu, F., Liao, K., Fu, M., Hu, G., Kolattukudy, P. & Buch, S., 14 Jul 2014, In : Nature Communications. 5, 4386.

Research output: Contribution to journalArticleResearchpeer-review

Monocyte Chemoattractant Proteins
monocytes
MicroRNAs
Chemical activation
activation
51 Citations (Scopus)

Molecular determinants mediating gating of transient receptor potential canonical (TRPC) channels by stromal interaction molecule 1 (STIM1)

Lee, K. P., Choi, S., Hong, J. H., Ahuja, M., Graham, S., Ma, R., So, I., Shin, D. M., Muallem, S. & Yuan, J. P., 7 Mar 2014, In : Journal of Biological Chemistry. 289, 10, p. 6372-6382 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Transient Receptor Potential Channels
Molecules
Charge coupled devices
Stromal Interaction Molecule 1
2013
11 Citations (Scopus)

Attenuated mesangial cell proliferation related to store-operated Ca 2+ entry in aged rat: The role of STIM 1 and Orai 1

Shen, B., Zhu, J., Zhang, J., Jiang, F., Wang, Z., Zhang, Y., Li, J., Huang, D., Ke, D., Ma, R. & Du, J., 1 Dec 2013, In : Age. 35, 6, p. 2193-2202 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Cell Proliferation
Biological Phenomena
Thapsigargin
Glomerular Filtration Rate
29 Citations (Scopus)

Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells

Wang, Y., Ding, M., Chaudhari, S., Ding, Y., Yuan, J. P., Stankowska, D. L., He, S., Krishnamoorthy, R., Cunningham, J. T. & Ma, R., 3 May 2013, In : Journal of Biological Chemistry. 288, 18, p. 12852-12865 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Protein Kinase C
Reactive Oxygen Species
Acetates
Kidney
Phosphorylation
26 Citations (Scopus)

The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

Ding, Y., Stidham, R. D., Bumeister, R., Trevino, I., Winters, A., Sprouse, M., Ding, M., Ferguson, D. A., Meyer, C. J., Christian Wigley, W. & Ma, R., 1 Jan 2013, In : Kidney International. 83, 5, p. 845-854 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glomerular Filtration Rate
Angiotensin II
Renal Plasma Flow
Inulin
2012
13 Citations (Scopus)

Canonical transient receptor potential channels in diabetes

Graham, S., Yuan, J. P. & Ma, R., 1 Feb 2012, In : Experimental Biology and Medicine. 237, 2, p. 111-118 8 p.

Research output: Contribution to journalReview articleResearchpeer-review

Transient Receptor Potential Channels
Medical problems
Proteins
Calcium Signaling
Diabetic Nephropathies
20 Citations (Scopus)

Renal protection of in vivo administration of tempol in streptozotocin-induced diabetic rats

Luan, J., Li, W., Han, J., Zhang, W., Gong, H. & Ma, R., 4 Jul 2012, In : Journal of Pharmacological Sciences. 119, 2, p. 167-176 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Streptozocin
Kidney
Transforming Growth Factors
Malondialdehyde
Messenger RNA
15 Citations (Scopus)

Transient Focal Cerebral Ischemia Induces Long-term Cerebral Vasculature Dysfunction in a Rodent Experimental Stroke Model

Winters, A., Taylor, J. C., Ren, M., Ma, R., Liu, R. & Yang, S., 1 Jun 2012, In : Translational Stroke Research. 3, 2, p. 279-285 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Transient Ischemic Attack
Rodentia
Theoretical Models
Stroke
Phenylephrine
2011
48 Citations (Scopus)

Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes

Graham, S., Gorin, Y., Abboud, H. E., Ding, M., Lee, D. Y., Shi, H., Ding, Y. & Ma, R., 1 Aug 2011, In : American Journal of Physiology - Cell Physiology. 301, 2

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Protein Kinase C
Reactive Oxygen Species
Glucose
Cultured Cells
52 Citations (Scopus)

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone

Ding, Y., Winters, A., Ding, M., Graham, S., Akopova, I., Muallem, S., Wang, Y., Hong, J. H., Gryczynski, Z., Yang, S., Birnbaumer, L. & Ma, R., 9 Sep 2011, In : Journal of Biological Chemistry. 286, 36, p. 31799-31809 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Vasoconstrictor Agents
Vascular Smooth Muscle
Knockout Mice
Muscle Cells
Smooth Muscle Myocytes
2010
53 Citations (Scopus)

Canonical Transient Receptor Potential 6 (TRPC6), a redox-regulated cation channel

Graham, S., Ding, M., Ding, Y., Sours-Brothers, S., Luchowski, R., Gryczynski, Z., Yorio, T., Ma, H. & Ma, R., 23 Jul 2010, In : Journal of Biological Chemistry. 285, 30, p. 23466-23476 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Arginine Vasopressin
Oxidation-Reduction
Cations
Vasopressin Receptors
Ethylmaleimide